3686-55-3

Usage

Uses

Used in Food Industry:
Methyl 2-ethoxybenzoate is used as a flavoring agent for its sweet, floral, and fruity aroma, enhancing the taste and aroma of various food products.
Used in Cosmetic Industry:
Methyl 2-ethoxybenzoate is used as a fragrance in cosmetics, adding a pleasant scent to products such as perfumes, lotions, and personal care items.
Used in Chemical Synthesis:
Methyl 2-ethoxybenzoate serves as an intermediate in the synthesis of other chemicals, contributing to the production of various compounds.
Used as a Solvent:
Methyl 2-ethoxybenzoate is utilized as a solvent in certain applications, taking advantage of its ability to dissolve other substances.
Safety Precautions:
It is important to handle and store Methyl 2-ethoxybenzoate with care, as it can be harmful if swallowed, inhaled, or comes into contact with the skin. Proper safety measures should be taken to minimize potential risks.

InChI:InChI=1/C10H12O3/c1-3-13-9-7-5-4-6-8(9)10(11)12-2/h4-7H,3H2,1-2H3

Upstream product

• 64-67-5 diethyl sulfate 
• 119-36-8 methyl salicylate 
• 74-96-4 ethyl bromide 
• 75-03-6 ethyl iodide 
• 67-56-1 methanol 
• 134-11-2 2-ethoxybenzoic acid 

Downstream Products

• 938-73-8 2-ethoxybenzamide 
• 134-11-2 2-ethoxybenzoic acid 
• 89-44-1 3-(2-ethoxyphenyl)-3-oxopropanenitrile 
• 200575-17-3 methyl 5-(chlorosulfonyl)-2-ethoxybenzoate 
• 19982-38-8 2-(o.etossifenil)-5-mercapto-1,3,4-oxadiazolo 
• 931911-75-0 1-(4-bromophenyl)-2-(5-(2-ethoxyphenyl)-1,3,4-oxadiazol-2-ylthio)ethanone 
• 838814-08-7 2-(5-(2-ethoxyphenyl)-1,3,4-oxadiazol-2-ylthio)-1-phenylethanone 
• 69-72-7 salicylic acid 
• 21018-13-3 2-ethoxybenzoic acid hydrazide 
• 108463-20-3 5,6-Dihydro-2-(2-ethoxyphenyl)-4H-naphtho<1,2-b>pyran-4-one 
• 108463-10-1 1-(2-Ethoxyphenyl)-3-(1,2,3,4-tetrahydro-1-oxo-2-naphthalenyl)-1,3-propanedione 
• 19982-41-3 N'-(2-ethoxy-benzoyl)-hydrazinecarbodithioic acid; potassium salt 

Relevant academic research and scientific papers

Process for preparing O-ethoxybenzoic acid chloride (by machine translation)

The method comprises the following steps of (1) ethylation reaction, (2) alkali hydrolysis reaction and (3) acyl chlorination reaction, and is simple in reaction step, strong in operability, mild in reaction conditions, simple in process, easy to control, convenient to use and capable of easily controlling the byproduct HCl and CO. 2 The method is simple in process, convenient to operate, low in raw material cost, high in yield, good in quality and convenient for industrial production. (by machine translation)

SULPHAMOYLARYL DERIVATIVES AND USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF LIVER FIBROSIS

Potent 5-HT2B antagonist of Formula (A), including stereochemically isomeric forms, and salts, hydrates, solvates thereof and their use wherein R1 to R4 and Ar have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them, alone or in combination with other drugs, in fibrosis and/or cirrhosis prevention or therapy.

Ultrasound-assisted, one-pot, three-component synthesis and antibacterial activities of novel indole derivatives containing 1,3,4-oxadiazole and 1,2,4-triazole moieties

Thirteen novel indole derivatives were efficiently synthesized through ultrasound irradiation by using 4-amino-5-(1H-indol-3-yl)-4H-[1,2,4]triazole-3-thiol (8) and 2-mercapto-5-substituted-1,3,4-oxadiazoles (5a-m). Compared with conventional and microwave methods, yields increased to 82-93%, and reaction times decreased to 15-35 min. The structures of these novel compounds were characterized by spectral data and elemental analysis. Two out of the synthesized compounds (10f and 10l) exhibited excellent activity against Staphylococcus aureus and Escherichia coli, and thus warrant further research.

Design, synthesis, in silico molecular docking and biological evaluation of novel oxadiazole based thiazolidine-2,4-diones bis-heterocycles as PPAR-γ agonists

A library of novel 1,3,4-oxadiazole and 2-4-thiazolidinedione based bis-heterocycles 7 (a-r) has been synthesized which exhibited significant PPAR-?3 transactivation and blood glucose lowering effect comparable with the standard drugs Pioglitazone and Rosiglitazone. Compounds 7m and 7r did not cause body weight gain and were found to be free from hepatotoxic and cardiotoxic side effects. Compounds 7m and 7r increased PPAR-?3 gene expression by 2.10 and 2.00 folds, respectively in comparison to the standard drugs Pioglitazone (1.5 fold) and Rosiglitazone (1.0 fold). Therefore the compounds 7m and 7r may be considered as potential candidates for development of new antidiabetic agents.

Synthesis, biological evaluation and molecular docking studies of novel 2-(1,3,4-oxadiazol-2-ylthio)-1-phenylethanone derivatives

In present study, a series of new 2-(1,3,4-oxadiazol-2-ylthio)-1- phenylethanone derivatives (6a-6x) as potential focal adhesion kinase (FAK) inhibitors were synthesized. The bioassay assays demonstrated that compound 6i showed the most potent activity, which inhibited the growth of MCF-7 and A431 cell lines with IC50 values of 140 ± 10 nM and 10 ± 1 nM, respectively. Compound 6i also exhibited significant FAK inhibitory activity (IC50 = 20 ± 1 nM). Docking simulation was performed to position compound 6i into the active site of FAK to determine the probable binding model.

Identification of a potent new chemotype for the selective inhibition of PDE4

A series of substituted 3,6-diphenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines were prepared and analyzed as inhibitors of phosphodiesterase 4 (PDE4). Synthesis, structure-activity relationships, and the selectivity of a highly potent analogue against related phosphodiesterase isoforms are presented.

Process for preparing sildenafil

A process for the preparation of a compound of formula (I): STR1 which comprises cyclization of a compound of formula (II): STR2