36951-49-2

Upstream product

• 2299-73-2 N,N-bis(4-methoxybenzylidene)hydrazine 
• 5349-28-0 thiocyanato-acetic acid ethyl ester 
• 36951-42-5 (2-(4-methoxyphenyl)methylene)hydrazolyl-1,3-thiazolidin-4-one 
• 123-11-5 4-methoxy-benzaldehyde 
• 36951-42-5 2-(2-(4-methoxybenzylidene)hydrazinyl)thiazol-4(5H)-one 
• 32003-36-4 2-hydrazino-1,3-thiazol-4(5H)-one 
• 4334-74-1 4-methoxybenzylidene thiosemicarbazone 

Downstream Products

• 264195-80-4 2-[N'-(4-methoxy-benzylidene)-hydrazino]-7-(4-methoxy-phenyl)-5-oxo-5H-pyrano[2,3-d]thiazole-6-carbothioic acid amide 
• 264195-85-9 3-(4-Methoxy-phenyl)-6-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-thiazolo[2,3-c][1,2,4]triazol-5-one 
• 264195-83-7 3,7-bis-(4-methoxy-phenyl)-5-oxo-5H-4-oxa-8-thia-1,2,3a-triaza-cyclopenta[a]indene-6-carbothioic acid amide 
• 264195-87-1 3,7-bis-(4-methoxy-phenyl)-6-(4-oxo-4,5-dihydro-thiazol-2-yl)-4-oxa-8-thia-1,2,3a-triaza-cyclopenta[a]inden-5-one 
• 264195-89-3 7-(4-Methoxy-phenyl)-2-{N'-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazino}-6-(4-oxo-4,5-dihydro-thiazol-2-yl)-pyrano[2,3-d]thiazol-5-one 

Relevant academic research and scientific papers

Reactions of Cyanothioacetamide Derivatives with 2-Hydrazinothiazol-4(5H)-one: Synthesis, Cyclization and Biological Evaluation of Several New Annelated Pyran, Thiazole, 1,2,4-Triazole and 1,2,4-Triazine Derivatives

The thiocarboxamidocinnamonitriles (2) reacted with 2-hydrazinothiazol-4(5H)-one (3) to afford the corresponding pyrano[2,3-d]thiazoles (6). Compounds 6 were used for the synthesis of several new annelated pyran, thiazole, 1,2,4-triazole and 1,2,4-triazine derivatives via their reactions with chloroacetic acid, ethyl chloroformate, diethyl oxalate and acetylacetone. Structures were established based on elemental and spectral data studies. Some of the newly synthesized heterocyclic derivatives were tested for their antimicrobial activity.