370-76-3

Basic information

• Product Name: 1-(4-Fluorophenyl)-2-phenylethane
• Synonyms: 1-(4-Fluorophenyl)-2-phenylethane;1-Fluoro-4-(2-phenylethyl)benzene;4-Fluorobibenzyl
• CAS NO: 370-76-3
• Molecular Formula: C₁₄H₁₃F
• Molecular Weight: 0
• Mol File: 370-76-3.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 264.2°C at 760 mmHg
• Flash Point: 121.4°C
• Appearance: /
• Density: 1.069g/cm³
• Vapor Pressure: 0.0161mmHg at 25°C
• Refractive Index: 1.557
• CAS DataBase Reference: 1-(4-Fluorophenyl)-2-phenylethane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Fluorophenyl)-2-phenylethane(370-76-3)
• EPA Substance Registry System: 1-(4-Fluorophenyl)-2-phenylethane(370-76-3)

Safety Data

• Hazardous Substances Data: 370-76-3(Hazardous Substances Data)

Usage

General Description

1-(4-Fluorophenyl)-2-phenylethane, also known as 4-Fluoroamphetamine, is a synthetic compound that belongs to the amphetamine class of chemicals. Its molecular formula is C16H15F, and it has a molecular weight of 227.29 g/mol. The chemical is a psychoactive drug and acts as a stimulant, affecting the central nervous system and producing feelings of euphoria, alertness, and increased energy. It is known to have similar effects to other amphetamines, such as increased heart rate, elevated blood pressure, and decreased appetite. 4-Fluoroamphetamine is also reported to have potential for abuse and addiction and is often used recreationally. Due to its psychoactive and stimulant properties, it is considered a controlled substance in many countries and is illegal to possess or distribute without a prescription.

InChI:InChI=1/C14H13F/c15-14-10-8-13(9-11-14)7-6-12-4-2-1-3-5-12/h1-5,8-11H,6-7H2

Upstream product

• 405-29-8 (4-fluorophenyl)phenylacetylene 
• 330-97-2 N-(4-fluorobenzyl)-2-phenylacetamide 
• 352-32-9 p-fluorotoluene 
• 100-39-0 benzyl bromide 
• 459-46-1 4-Fluorobenzyl bromide 
• 622-24-2 2-phenylethyl chloride 
• 352-13-6 4-flourophenylmagnesium bromide 
• 108-86-1 bromobenzene 
• 405-99-2 para-fluorostyrene 
• 103-63-9 1-phenyl-2-bromoethane 
• 100-42-5 styrene 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 1065498-70-5 2-(2-(4-fluorophenyl)ethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 108-90-7 chlorobenzene 

Relevant articles and documents

Chemoselective Hydrogenation of Alkynes to (Z) -Alkenes Using an Air-Stable Base Metal Catalyst

A highly selective hydrogenation of alkynes using an air-stable and readily available manganese catalyst has been achieved. The reaction proceeds under mild reaction conditions and tolerates various functional groups, resulting in (Z)-alkenes and allylic alcohols in high yields. Mechanistic experiments suggest that the reaction proceeds via a bifunctional activation involving metal-ligand cooperativity.

Cobalt-catalyzed (Z)-selective semihydrogenation of alkynes with molecular hydrogen

Cobalt-catalyzed highly (Z)-selective semihydrogenation of alkynes using molecular H2 was developed using commercially available and cheap cobalt precursors. A variety of (Z)-alkenes were obtained in moderate to excellent selectivities [(Z)-alkene/(E)-alkene/alkane ratio up to >99 : 1 : 1] and it was found that the readily available ethylenediamine ligand is crucial in determining the selectivity.

A cobalt-catalyzed alkene hydroboration with pinacolborane

An extremely efficient cobalt catalyst for the hydroboration of both vinylarenes and aliphatic α-olefins with pinacolborane is described, providing the anti-Markovnikov products with excellent regio- and chemoselectivity, broad functional-group tolerance,