37033-06-0 Usage
Uses
Used in Pharmaceutical Industry:
1H-furo[3,4-b]indol-3(4H)-one is utilized as a pharmacological agent for its potential as an adenosine A2A receptor antagonist. This application is significant in the development of treatments for various conditions, given the receptor's role in physiological processes.
Additionally, it is considered as an anti-cancer agent, indicating its potential role in oncology for the development of novel therapeutics targeting cancer cells. 1H-furo[3,4-b]indol-3(4H)-one's ability to interact with specific biological targets makes it a valuable asset in the advancement of cancer treatment strategies.
Used in Medicinal Chemistry Research:
In the realm of medicinal chemistry, 1H-furo[3,4-b]indol-3(4H)-one serves as a subject of interest for its unique structural properties. Researchers explore its potential to be modified and optimized for various therapeutic applications, thereby contributing to the discovery of new drugs and drug classes.
Used in Chemical Synthesis:
Beyond its direct applications, 1H-furo[3,4-b]indol-3(4H)-one is also used as a key intermediate in the synthesis of other complex organic compounds. Its reactivity and structural features make it a versatile building block in organic chemistry for creating a wide array of molecules with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 37033-06-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,0,3 and 3 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 37033-06:
(7*3)+(6*7)+(5*0)+(4*3)+(3*3)+(2*0)+(1*6)=90
90 % 10 = 0
So 37033-06-0 is a valid CAS Registry Number.
37033-06-0Relevant academic research and scientific papers
A regioselective facile synthesis of furo[3,4-b]carbazolones: Application to the total synthesis of mafaicheenamine e and claulansine D
Mal, Dipakranjan,Roy, Joyeeta
, p. 6344 - 6352 (2015/06/08)
1-Hydroxycarbazole-2,3-dicarboxylates have been shown to undergo chemoselective reductive cyclization to furo[3,4-b]carbazolones on reaction with LiAlH4. One of the furocarbazolones is utilized to accomplish the first total synthesis of claulansine D and mafaicheenamine E in 9 and 6 steps respectively. The other key steps of the syntheses are addition of an allylic indium reagent and CC double bond isomerization.
A new synthetic route to indoloquinones: Formal synthesis of ellipticine
Mal, Dipakranjan,Senapati, Bidyut K.,Pahari, Pallab
, p. 994 - 996 (2007/10/03)
The anionic [4+2] cycloaddition of furoindolones with arynes and quinol ethers is introduced as an efficient strategy for the synthesis of indoloquinones. The utility of the strategy is exemplified by a very short synthesis of elipticine.
