372-06-5

Basic information

• Product Name: bis(trifluoromethyl)trisulfide
• Synonyms: bis(trifluoromethyl)trisulfide;Bis(trifluoromethyl)trisulfane;Bis(trifluoromethyl) pertrisulfide
• CAS NO: 372-06-5
• Molecular Formula: C₂F₆S₃
• Molecular Weight: 234.2068192
• Mol File: 372-06-5.mol

Chemical Properties

• Boiling Point: 41.3°Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.719g/cm³
• Vapor Pressure: 422mmHg at 25°C
• Refractive Index: 1.444
• CAS DataBase Reference: bis(trifluoromethyl)trisulfide(CAS DataBase Reference)
• NIST Chemistry Reference: bis(trifluoromethyl)trisulfide(372-06-5)
• EPA Substance Registry System: bis(trifluoromethyl)trisulfide(372-06-5)

Safety Data

• Hazardous Substances Data: 372-06-5(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
Bis(trifluoromethyl)trisulfide serves as a reagent in organic synthesis, contributing to the formation of a variety of sulfur-containing compounds. Its unique properties make it a valuable component in the creation of complex organic molecules.
Used in Rubber Industry:
As a vulcanizing agent, bis(trifluoromethyl)trisulfide plays a crucial role in the rubber industry. It helps in the process of vulcanization, which enhances the elasticity, strength, and durability of rubber products.
Used in Pesticide Production:
Bis(trifluoromethyl)trisulfide is utilized as a precursor in the synthesis of pesticides. Its involvement in the production process contributes to the development of effective pest control agents.
Used in Pharmaceutical Industry:
bis(trifluoromethyl)trisulfide also finds application in the pharmaceutical sector, where it is used in the synthesis of various drugs. Its reactivity and ability to form sulfur-containing compounds make it a useful component in medicinal chemistry.

InChI:InChI=1/C2F6S3/c3-1(4,5)9-11-10-2(6,7)8

Upstream product

• 75-15-0 carbon disulfide 
• 421-17-0 Trifluoromethylsulfenyl chloride 
• 75-11-6 diiodomethane 
• 3872-23-9 Copper(I) trifluoromethanethiolate 
• 676-71-1 dimethyl(bromo)arsine 
• 420-32-6 thiocarbonyl fluoride 
• 7783-60-0 sulfur tetrafluoride 
• 1717-50-6 tetrafluoro-1,3-dithiaetane 
• 2314-97-8 iodotrifluoromethane 
• 65844-06-6 Li⁽¹⁺⁾*CF₃S^(1-)=LiSCF₃ 
• 1840-68-2 cis-SF₄(OCF₃)2 
• 13780-57-9 pentafluorosulfanyl chloride 
• 57934-37-9 fluoro(trifluoromethyl)disulfane 
• 55860-39-4 trifluoromethyldisulfane 

Downstream Products

• 111-65-9 octane 
• 544-40-1 Dibutyl sulfide 
• 629-45-8 dibutyl disulfide 
• 7412-26-2 1-[(trifluoromethyl)thio]butane 
• 594-82-1 tetramethyl-2,2,3,3 butane 
• 352-93-2 diethyl sulphide 
• 420-32-6 thiocarbonyl fluoride 
• 691-05-4 ethyl-trifluoromethyl disulfide 
• 55882-01-4 Ethyltrifluormethyltrisulfan 
• 145372-19-6 C₅H₉F₃S₃ 
• 371-78-8 bis-(trifluoromethyl)sulfide 
• 372-64-5 Bis(trifluoromethyl)disulfid 
• 7704-34-9 sulfur 

Relevant articles and documents

Synthesis of bis(trifluoromethyl)trisulfide and bis(trifluoromethylthio)selenide

The use of 4-dimethylaminopyridine as a catalyst in the reaction of trifluoromethylsulfenyl chloride with hydrogen sulfide at -78 deg C cuts down the time of reaction from 30 d to 1 d and gives up to 70percent yield of bis(trifluoromethyl)trisulfide (1).Similarly, bis(trifluoromethylthio)selenide (2) can be prepared from hydrogen selenide and trifluoromethylsulfenyl chloride.The influence of other catalysts on the course of the reaction, the formation of unusual by-products, the NMR and mass spectral data of 1 and 2 are presented in this paper.

Reactions of trifluoromethylthiocopper with halomethanes

The reaction of trifluoromethylthiocopper with halomethanes, namely di-and triiodo-, dibromodichloro-, dibromochlorofluoro-, dibromo-difluoro-, bromochlorofluoro-, phenyltrichloro-, bromocyano-and dibromofluoro-methanes, has been investigated in detail. In addition to the expected compounds, the formation of unusual products such as bis (trifluoromethyl) trithiocarbonate, dimethyl (trifluoromethylthio) benzene, bis (trifluoromethylthio) fluoromethane, (trifluoromethylthio) carbonyl fluoride, carbon disulfide, carbon tetrachloride, trifluoromethylthio-benzoate, etc. was observed. In some cases, bis (trifluoromethylthio) mercury has been used instead of trifluoromethylthiocopper. The mechanism of formation of the various products and their mass spectral fragmentation behavior are described.

Synthesis and biological screening of trifluoromethylthioarsenicals

The title compounds have been prepared from the reaction of trifluoromethylthiocopper and alkyl mono- and di-haloarsines.This communication describes their synthesis, biological screening and mass spectral fragmentation behavior.

Simultaneous scission of C-S and S-S bonds of bis(trifluoromethyl)trisulfide by Grignard reagents

Trifluoromethyl mono-, di- and tri-sulfides, and alkyl sulfides and disulfides, as well as dimerized products, are formed as a result of the simultaneous cleavage of the C-S and S-S bonds of bis(trifluoromethyl)trisulfide by Grignard reagents at -78 deg C.The formation of various products has been rationalized on the basis of the involvement of free radicals.

REACTION OF ORGANIC COMPOUNDS WITH THE SF4-HF-HALOGENATING SYSTEM IX. REACTIONS OF PERFLUOROOLEFINS WITH THE SF4-HF-S2Cl2 SYSTEM

The reaction of perfluoroolefins with the SF4-HF-S2Cl2 system leads to perfluoroalkanesulfenyl chlorides, thiosulfenyl chlorides, and polysulfides.Preparative methods were developed for the production of trifluoromethanesulfenyl, perfluoroethanesulfenyl, perfluoro(1-methylethane)sulfenyl, and perfluoro(1-methylheptane)sulfenyl chlorides and the corresponding sulfonyl chlorides.

The reactions of uranium hexafluoride with hydrogen sulfide and with carbon disulfide

Uranium hexafluoride reacts with hydrogen sulfide at 25° to produce uranium tetrafluoride, sulfur tetrafluoride, and hydrogen fluoride. Uranium hexafluoride reacts with carbon disulfide vapor at 25° to produce uranium tetrafluoride, sulfur tetrafluoride, bistrifluoromethyl disulfide [(CF3)2S2], and bistrifluoromethyl trisulfide [(CF3)2S3], and at elevated temperatures the reaction also produces sulfur hexafluoride and tetrafluoromethane, CF4. When uranium hexafluoride vapor reacts with carbon disulfide vapor at 25° in the presence of helium as a diluent, the favored perfluoroalkyl product is bistrifluoromethyl trisulfide. Uranium hexafluoride is compared with other metal fluorides with respect to their reactions with carbon disulfide.