374791-63-6

Basic information

• Product Name: α,α-dimethyl-N-[4-oxo-1-phenylcyclohexyl]-3,5-bis(trifluoromethyl)benzeneacetamide
• Synonyms: α,α-dimethyl-N-[4-oxo-1-phenylcyclohexyl]-3,5-bis(trifluoromethyl)benzeneacetamide
• CAS NO: 374791-63-6
• Molecular Weight: 471.443
• Mol File: 374791-63-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: α,α-dimethyl-N-[4-oxo-1-phenylcyclohexyl]-3,5-bis(trifluoromethyl)benzeneacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: α,α-dimethyl-N-[4-oxo-1-phenylcyclohexyl]-3,5-bis(trifluoromethyl)benzeneacetamide(374791-63-6)
• EPA Substance Registry System: α,α-dimethyl-N-[4-oxo-1-phenylcyclohexyl]-3,5-bis(trifluoromethyl)benzeneacetamide(374791-63-6)

Safety Data

• Hazardous Substances Data: 374791-63-6(Hazardous Substances Data)

Upstream product

• 289686-69-7 2-(3,5-bis-trifluoromethyl-phenyl)-2-methyl-propionyl chloride 
• 374794-41-9 4-Oxo-1-phenylcyclohexylamine Hydrochloride 
• 334477-48-4 methyl 2-(3,5-bis(trifluoromethyl)phenyl)-2-methylpropanoate 
• 75945-91-4 4-oxo-1-phenylcyclohexanecarboxylic acid 
• 95261-39-5 4-amino-4-phenylcyclohexan-1-one 
• 289686-70-0 α,α-Dimethyl-3,5-bis(trifluoromethyl)benzeneacetic Acid 

Downstream Products

• 374796-26-6 (RS)-α,α-dimethyl-N-{1-phenyl-4-[(trimethylsilyl)oxy]cyclohex-3-enyl}-3,5-bis(trifluoromethyl)benzeneacetamide 

Relevant articles and documents

Cyclohexane derivatives and their use as therapeutic agents

The present invention relates compounds of formula (I), wherein ring A is a phenyl or pyridyl ring; X represents a linker selected from the group consisting of formulae: (a), (b), (c), (d), and (e); and R1, R2, R3, R4, R5, R6, R7, R13, R14, R15, R16, R17, R21a and R21b are as defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.