37614-73-6

Upstream product

• 4105-61-7 3-O-Benzyl-5,6-didehydro-5,6-dideoxy-1,2-isopropyliden-α-D-xylo-hexofuranose 
• 3254-32-8 6-O-benzoyl-1,2-O-isopropylidene-α-D-glucofuranose 
• 286011-06-1 1,2:5,6-di-O-isopropylidene-α-D-galactofuranose 
• 98-88-4 benzoyl chloride 
• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 182412-45-9 Benzoic acid (3aR,5R,6S,6aR)-2,2-dimethyl-5-((R)-2-thioxo-[1,3]dioxolan-4-yl)-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester 
• 81712-62-1 Benzoic acid (3aR,5R,6S,6aR)-5-((R)-1,2-bis-benzhydryloxy-ethyl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester 
• 13964-22-2 3-O-benzoyl-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 

Downstream Products

• 3254-32-8 6-O-benzoyl-1,2-O-isopropylidene-α-D-glucofuranose 
• 66954-56-1 O⁵,O⁶-diacetyl-O³-benzoyl-O¹,O²-isopropylidene-α-D-glucofuranose 
• 55263-77-9 O³,O⁶-dibenzoyl-O¹,O²-isopropylidene-O⁵-(toluene-4-sulfonyl)-α-D-glucofuranose 
• 81058-34-6 6-Azido-3-O-benzoyl-6-desoxy-1,2-O-isopropyliden-4-O-(methylsulfonyl)-α-D-glucopyranose 
• 81058-60-8 6-Azido-6-desoxy-1,2-O-isopropyliden-4-O-(p-tolylsulfonyl)-α-D-glucopyranose 
• 81058-59-5 6-Azido-6-desoxy-1,2-O-isopropyliden-3-O-(p-tolylsulfonyl)-α-D-glucopyranose 
• 81058-33-5 6-Azido-3-O-benzoyl-6-desoxy-1,2-O-isopropyliden-α-D-glucopyranose 
• 81058-32-4 6-Azido-3-O-benzoyl-6-desoxy-1,2-O-isopropyliden-α-D-glucofuranose 
• 4105-61-7 3-O-Benzyl-5,6-didehydro-5,6-dideoxy-1,2-isopropyliden-α-D-xylo-hexofuranose 
• 55169-76-1 3,6-di-O-benzoyl-1,2-O-isopropylidene-α-D-glucofuranose 
• 81712-62-1 Benzoic acid (3aR,5R,6S,6aR)-5-((R)-1,2-bis-benzhydryloxy-ethyl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester 
• 983-79-9 benzophenone azine 
• 81058-31-3 3-O-benzoyl-1,2-O-isopropylidene-6-O-p-toluenesulfonyl-α-D-glucofuranose 

Relevant academic research and scientific papers

Thioglucose compound and preparation method thereof

The invention provides a thioglucose compound which has the following general formula: Wherein R is selected from H or acetyl. The preparation method of the thioglucose compound is easy to obtain, low in production cost and suitable for industrial product

Ultrasound-assisted selective deprotection of terminal acetonides catalyzed by silica-supported boron trifluoride

An efficient and convenient method for the selective cleavage of terminal acetonides is described. Treatment of terminal acetonides in the presence of a wide range of functional groups with silica-supported boron trifluoride as a catalyst furnished the corresponding diols in 82-95% yield under ultrasound irradiation conditions. The acid-labile p-methoxybenzyl group as a protecting group remained intact under the conditions employed to the present deprotection condition. Copyright Taylor & Francis Group, LLC.

Sulfuric acid immobilized on silica: an efficient reusable catalyst for selective hydrolysis of the terminal O-isopropylidene group of sugar derivatives

Sulfuric acid immobilized on silica proved to be an efficient catalyst for selective hydrolysis of the terminal O-isopropylidene group of sugar derivatives. The method is very simple and economic for large-scale synthesis in which the catalyst is recovered and reused for several runs. Reactions with di-O-isopropylidene derivatives of d-glucose, d-mannose, d-fructose and l-sorbose led to the formation of the corresponding mono-O-isopropylidene derivatives in good to excellent yields.

Catalytic asymmetric dihydroxylation of olefins using polysulfone-based novel microencapsulated osmium tetroxide

A polysulfone based novel polymer-supported osmium catalyst has been developed. The catalyst was prepared from commercially available polysulfone, based on a microencapsulation technique and was employed in the asymmetric dihydroxylation of various olefins using (DHQD)2PHAL as the chiral ligand and NMO as the co-oxidant in H2O-acetone-CH3CN (1:1:1). The catalyst was recovered by simple filtration and was reused to obtain excellent yields with good enantioselectivity up to five times.

Mild, efficient, and selective cleavage of trityl ethers with antimony trichloride

Selective detritylation is quite crucial in synthetic chemistry. A mild and efficient procedure for selective hydrolysis of trityl ethers in the presence of other frequently used hydroxy protecting groups: TBDPS, Bz, Bn, Ac and Ts with antimony trichloride was described and 5′-trityl uridine was detritylated smoothly too. Copyright Taylor & Francis Group, LLC.

Selective deprotection of terminal isopropylidene acetals and trityl ethers using HClO4 supported on silica gel

Terminal isopropylidene acetals are selectively cleaved to the corresponding 1,2-diols in good to excellent yields in 6-24 h at room temperature by using the 'HClO4?SiO2' reagent system. Likewise, trityl ethers are readily cleaved to the corresponding alcohols in good to excellent yields within 2-3 h at room temperature. Work-up involves merely filtration of the reagent followed by purification of the crude product.

Polymer-supported ferric chloride as a heterogeneous catalyst for chemoselective deprotection of acetonides

Acetonides undergo chemoselective deprotection to afford the corresponding 1,2-diols in excellent yields using polymer (PVP)-supported ferric chloride as a heterogeneous catalyst in acetonitrile-dichloromethane at room temperature.

Chemoselective deprotection of acid labile primary hydroxyl protecting groups under CBr4-photoirradiation conditions

The CBr4-photoirradiation in methanol generates a controlled source of HBr, which can chemoselectively deprotect commonly used hydroxyl-protecting groups in saccharides and nucleosides, such as tert-butyldimethylsilyl, isopropylidene, benzylidene and triphenyl ethers in the presence of other acid-labile functional groups. Graphical Abstract.

A one-pot strategy for synthesis of 5-O-(α-D-Arabinofuranosyl)-6-O-(β-D-galactofuranosyl)-D- galactofuranose present in motif E of the Mycobacterium tuberculosis cell wall

5-O-(α-D-Arabinofuranosyl)-6-O-(β-D-galactofuranosyl)-D- galactofuranose 6 present in motif E of the Macobacterium tuberculosis cell wall has been regio- and stereospecifically synthesized using 3-O-benzoyl-1,2-O-isopropylidine-α-D-galactofuranose (10) as the glycosyl acceptor by the trichloroacetamidate method in a one-pot manner. The diol glycosyl acceptor 10 was smoothly derived from 1,2:5,6-di-O-isopropylidene-α-D-galactofuranose (8) by 3-O-benzoylation and then selective 5,6-O-deacetonation. The preparation of 8 was greatly improved by increasing the ratio of DMF to acetone and using a solid-supported catalyst.

A mild and efficient method for chemoselective deprotection of acetonides by bismuth(III) trichloride

Acetonides undergo chemoselective deprotection to afford the corresponding 1,2-diols in excellent yields using bismuth trichloride in acetonitrile/dichloromethane at ambient temperature.