3770-48-7

Basic information

• Product Name: 4-Methyl-9H-carbazole
• Synonyms: 4-Methyl-9H-carbazole
• CAS NO: 3770-48-7
• Molecular Formula: C₁₃H₁₁N
• Molecular Weight: 181.2331
• Mol File: 3770-48-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 369.1°Cat760mmHg
• Flash Point: 165.4°C
• Appearance: /
• Density: 1.19g/cm³
• Vapor Pressure: 2.59E-05mmHg at 25°C
• Refractive Index: 1.736
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 4-Methyl-9H-carbazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methyl-9H-carbazole(3770-48-7)
• EPA Substance Registry System: 4-Methyl-9H-carbazole(3770-48-7)

Safety Data

• Hazardous Substances Data: 3770-48-7(Hazardous Substances Data)

Usage

Uses

4-Methylcarbazole can be used to analyze chemosensory markers in cigarette smoke from different tobacco varieties by GCxGC-TOFMS and chemometrics.

InChI:InChI=1/C13H11N/c1-9-5-4-8-12-13(9)10-6-2-3-7-11(10)14-12/h2-8,14H,1H3

Upstream product

• 1924-79-4 2-azido-2'-methyl-1,1'-biphenyl 
• 86560-87-4 2,2'-diamino-6,6'-dimethylbiphenyl 
• 108-44-1 1-amino-3-methylbenzene 
• 822-87-7 2-Chlorocyclohexanone 
• 615-36-1 2-bromoaniline 
• 1203-41-4 2-(2-methylphenyl)aniline 
• 16419-60-6 2-Methylphenylboronic acid 
• 95-50-1 1,2-dichloro-benzene 
• 586-96-9 Nitrosobenzene 
• 556812-44-3 2-methyl-6-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 620-26-8 3-nitrosotoluene 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 
• 59-88-1 phenylhydrazine hydrochloride 
• 591-24-2 3-Methylcyclohexanone 

Downstream Products

• 126480-00-0 9-benzenesulfonyl-4-(1-naphthylethyl)carbazole 
• 126480-01-1 9-benzenesulfonyl-4-(2-naphthylethyl)carbazole 

Relevant articles and documents

Convenient One-Pot Synthesis of 9 H -Carbazoles by Microwave Irradiation Employing a Green Palladium-Based Nanocatalyst

An efficient palladium-catalyzed tandem reaction for the one-pot synthesis of 9 H -carbazoles under microwave irradiation is developed. This approach involves a sequential Buchwald-Hartwig amination and a direct arylation from affordable and inexpensive anilines and 1,2-dihaloarenes. For the development of this purpose, a novel and magnetically recoverable palladium nanocatalyst supported on a green biochar under ligand-free conditions is used. Compared to other existing palladium-based protocols, the present synthetic methodology shows a drastic reduction in reaction times and excellent compatibility with different functional groups allowing to obtain a small library of 9 H -carbazoles in high yields and with good regioselectivity. This procedure represents the first example in the direct synthesis of carbazoles using a heterogeneous palladium nanocatalyst from commercial precursors. To examine the application of this protocol, a direct and scalable synthesis of the bioactive carbazole alkaloid clausenalene from commercially available starting materials is described.

One-pot synthesis of carbazoles from cyclohexanones and arylhydrazine hydrochlorides under metal-free conditions

One-pot synthesis of carbazoles from cyclohexanones and arylhydrazine hydrochlorides is disclosed. Various substituted carbazoles were obtained in moderate to good yields via a sequence of condensation, cyclization and dehydrogenation under metal free conditions using molecular oxygen as an oxidant.

METHYL MIGRATION AND DEMETHYLATION IN THE 4,5-DIMETHYLCARBAZOLE SYNTHESIS BY TAUBER METHOD

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