3770-95-4

Basic information

• Product Name: CYCLOHEXYL CARBANILATE
• Synonyms: CYCLOHEXYL CARBANILATE;Cyclohexanol carbanilate;Cyclohexyl N-phenylcarbamate;Cyclohexyl phenylcarbamate;NSC 59905;Phenylcarbamic acid cyclohexyl ester
• CAS NO: 3770-95-4
• Molecular Formula: C₁₃H₁₇NO₂
• Molecular Weight: 219
• Mol File: 3770-95-4.mol
• Article Data: 30

Chemical Properties

• Melting Point: 85-86℃
• Boiling Point: 296℃
• Flash Point: 113℃
• Appearance: /
• Density: 1.10
• Vapor Pressure: 0.00145mmHg at 25°C
• Refractive Index: 1.545
• Storage Temp.: 2-8°C
• CAS DataBase Reference: CYCLOHEXYL CARBANILATE(CAS DataBase Reference)
• NIST Chemistry Reference: CYCLOHEXYL CARBANILATE(3770-95-4)
• EPA Substance Registry System: CYCLOHEXYL CARBANILATE(3770-95-4)

Safety Data

• Hazardous Substances Data: 3770-95-4(Hazardous Substances Data)

Usage

General Description

Cyclohexyl carbanilate is a chemical compound with the molecular formula C13H19NO2. It is a white crystalline solid with a slightly sweet odor. The compound is primarily used as a flavoring agent in the food industry, providing a fruity and creamy taste to products such as dairy, confectionery, and baked goods. Cyclohexyl carbanilate is also used in the production of perfumes and fragrances, contributing to its pleasant and long-lasting scent. Additionally, it has potential applications in the pharmaceutical industry for the synthesis of certain drugs and medications. The compound is considered to be relatively safe for use in food and consumer products when used in accordance with regulations and guidelines.

InChI:InChI=1/C13H17NO2/c15-13(14-11-7-3-1-4-8-11)16-12-9-5-2-6-10-12/h1,3-4,7-8,12H,2,5-6,9-10H2,(H,14,15)

Upstream product

• 55-21-0 benzamide 
• 108-93-0 cyclohexanol 
• 201230-82-2 carbon monoxide 
• 98-95-3 nitrobenzene 
• 98-88-4 benzoyl chloride 
• 62-53-3 aniline 
• 3422-01-3 tert-butyl phenylcarbamate 
• 590-28-3 potassium cyanate 
• 1919-48-8 2,4,6-triphenoxy-1,3,5-triazine 
• 108-86-1 bromobenzene 
• 591-50-4 iodobenzene 
• 124-38-9 carbon dioxide 
• 542-18-7 cyclohexyl chloride 
• 108-85-0 1-bromocyclohexane 

Downstream Products

• 23294-39-5 4-nitrophenylcarbamic acid cyclohexyl ester 
• 20995-16-8 cyclohexyl N-(4-aminophenyl)carbamate 
• 303158-03-4 (4-nitroso-phenyl)-carbamic acid cyclohexyl ester 

Relevant articles and documents

HIGH-PRESSURE SYNTHESIS OF CARBAMATES BY THE CARBONYLATION OF AROMATIC NITRO COMPOUNDS IN CYCLOHEXANOL

A study was carried out on the high-pressure carbonylation of nitrobenzene and 3-chloronitrobenzene by CO in cyclohexanol in the presence of PdCl2-FeCl3-pyridine with the formation of cyclohexyl-N-phenylcarbamate and cyclohexyl-N-3-chlorophenylcarbamate i

Synthesis, crystal structure and ab initio studies of cyclohexyl n-phenylcarbamate

Cyclohexyl N-phenylcarbamate, C13H17NO2 (I), which is a useful target for biotransformations by fungi, has been synthesized and the structure has been solved by X-ray diffraction. The crystals are triclinic, space group P

Carbon dioxide utilization in the efficient synthesis of carbamates by deep eutectic solvents (DES) as green and attractive solvent/catalyst systems

A green and eco-friendly solvent/catalyst system based on a deep eutectic solvent (DES) was devised and developed for the simple synthesis of carbamates through three-component coupling of amines, alkyl halides and carbon dioxide (CO2). It was found that choline chloride:zinc(ii) chloride ([ChCl][ZnCl2]2) was very proficient and effective for the activation and utilization of CO2 in carbamate formation reactions from a wide scope of amines. Surprisingly, this strategy provides the desired carbamates under atmospheric CO2 pressure at room temperature. In particular, both aromatic and aliphatic amines were effective and demonstrated excellent yields. Besides, the [ChCl][ZnCl2]2 exhibited very high stability and also could be reused for at least five consecutive cycles without any significant loss of activity. It is worth noting that this is the first solvent/catalyst system which can be recycled successfully from the reaction mixture.

One stone two birds: Cobalt-catalyzed in situ generation of isocyanates and benzyl alcohols for the synthesis of N-aryl carbamates

An efficient method for the synthesis of N-aryl carbamates from N-Boc-protected amines has been developed. The cobalt-catalyzed in situ generation of isocyanates from N-Boc-protected amines and benzyl alcohols from benzyl formates has been achieved for the first time, which in turn furnished the corresponding benzyl carbamates in moderate to high yields. The reaction was catalyzed by CoI2 with tris-(4-dimethylaminophenyl)-phosphine as the ligand and zinc powder as the reductant. The developed reaction conditions were found to be compatible for aromatic amines with both electron-donating and -withdrawing substituents.