37722-34-2Relevant articles and documents
A convenient and efficient preparation of β-substituted α-haloenones from diazodicarbonyl compounds
Lee, Yong Rok,Cho, Bang Sub,Kwon, Hyuk Jin
, p. 9333 - 9347 (2003)
Rhodium(II)-catalyzed reactions of cyclic diazodicarbonyl compounds with a variety of halides have been examined. With acid halides, β-acyloxy α-haloenones are produced in good yields. With benzyl halides, β-benzyloxy α-haloenones are obtained in good yie
Synthesis of novel derivatives of 7,8-dihydro-6H-imidazo[2,1-b][1,3]benzothiazol-5-one and their virus-inhibiting activity against influenza A virus
Galochkina, Anastasia V.,Bollikanda, Rakesh K.,Zarubaev, Vladimir V.,Tentler, Dmitry G.,Lavrenteva, Irina N.,Slita, Alexander V.,Chirra, Nagaraju,Kantevari, Srinivas
, (2018/12/13)
Influenza remains a highly pathogenic and hardly controlled human infection. The ability of selecting drug-resistant variants necessitates the search and development of novel anti-influenza drugs. Herein, we describe the synthesis and evaluation of a seri
A mild and regioselective method for α-bromination of β-keto esters and 1,3-diketones using bromodimethylsulfonium bromide (BDMS)
Khan, Abu T.,Ali, Md. Ashif,Goswami, Papori,Choudhury, Lokman H.
, p. 8961 - 8963 (2007/10/03)
Bromodimethylsulfonium bromide has been found to be an effective and regioselective reagent for α-monobromination of β-keto esters and 1,3-diketones. A wide variety of β-keto esters and 1,3-diketones undergo chemoselective α-monobromination with excellent yields at 0-5 °C or room temperature. The notable advantages of this protocol are no need of chromatographic separation, use of less hazardous reagent than molecular bromine, and no added base, Lewis acid, or other catalyst.
A convenient halogenation of α,β-unsaturated carbonyl compounds with OXONE and hydrohalic acid (HBr,HCl)
Kim, Kyoung-Mahn,Park, In-Hwan
, p. 2641 - 2644 (2007/10/03)
Mixtures of OXONE and hydrobromic acid or hydrochloric acid afford solutions of bromine or chlorine, respectively, α-Bromo- or α-chloro-α,β-unsaturated carbonyl compounds were prepared by addition of hydrobromic acid or hydrochloric acid to the mixture of
A new versatile route to the synthesis of novel pyrazole and fused pyrazole derivatives via intramolecular Michael reaction
El-Bermawy,Abdel Aal,El-Swah,Kadry,Al-Ashmawi
, p. 580 - 584 (2007/10/03)
Pyrazole moiety is contained in various biologically significant compounds. Therefore, we developed a synthetic route to different pyrazole derivatives which is described herein. The method shown in this work involves the utilization of active methylene c
PREPARATION AND ENOL ALLYL REARRANGEMENT OF POLYCHLORINATED DIMEDONE AND 4,4-DIMETHYL-1,3-CYCLOPENTANEDIONE DERIVATIVES
Buyck, L. De,Verhe, R.,Kimpe, N. De,Schamp, N.
, p. 307 - 322 (2007/10/02)
The 2-position in 5,5-dimethyl-1,3-cyclohexanedione (dimedone) and in 4,4-dimethyl-1,3-cyclopentanedione or their derivatives is completely and exclusively chlorinated with chlorine in dichloromethane.Dimethylformamide-hydrogen chloride mixtures, especial