37796-79-5

Usage

Uses

Used in Dye and Pigment Manufacturing:
2-NAPHTHALENAMINE, 6-METHYLis used as a key intermediate in the production of various dyes and pigments, contributing to their color intensity and stability.
Used in Pharmaceutical Production:
6-MNA serves as an important intermediate in the manufacturing of pharmaceuticals, playing a crucial role in the synthesis of certain medicinal compounds.
Used in Optical Brightener Production:
2-NAPHTHALENAMINE, 6-METHYLis utilized as an intermediate in the creation of optical brighteners, which are used to enhance the appearance of various materials by reflecting light more effectively.
Used in Antioxidant Production:
6-MNA is also employed in the synthesis of antioxidants, which are essential in various industries to prevent the deterioration of materials and products over time.
Given the mutagenic and carcinogenic properties of 2-NAPHTHALENAMINE, 6-METHYL-, it is imperative that its use is strictly controlled and exposure is minimized to ensure the safety of workers and the environment.

InChI:InChI=1/C11H11N/c1-8-2-3-10-7-11(12)5-4-9(10)6-8/h2-7H,12H2,1H3

Upstream product

• 17579-79-2 2-methyl-6-hydroxynaphthalene 
• 54357-08-3 6-nitro-2-methylnaphthalene 
• 64-19-7 acetic acid 
• 7499-66-3 6-Bromonaphthalen-2-amine 
• 75-16-1 methylmagnesium bromide 
• 15231-91-1 6-bromo-naphthalen-2-ol 
• 676-58-4 methylmagnesium chloride 
• 83008-10-0 N-(6-methyl-[2]naphthyl)-acetamide 
• 91-57-6 2-Methylnaphthalene 

Downstream Products

• 17579-79-2 2-methyl-6-hydroxynaphthalene 
• 37796-78-4 2-bromo-6-methylnaphthalene 
• 32721-06-5 2-(6-bromonaphthalen-2-yl)acetic acid 
• 305798-02-1 2-bromo-6-(bromomethyl)naphthalene 

Relevant academic research and scientific papers

Method for resolving chiral compound

The invention relates to the field of organic chemistry, in particular to a method for resolving a chiral compound. The method for splitting the chiral compound provided by the invention comprises thestep of carrying out addition reaction on a racemic compound shown as a formula A and azodicarbonic acid ester in the presence of a catalyst so as to provide an S-configuration compound shown as theformula A and an S-configuration compound shown as the formula C. According to the method, chiral phosphoric acid is used as a catalyst; good catalytic effect is achieved, and very wide substrate applicability is also achieved; the product and the recovered raw material can be obtained with excellent enantioselectivity, the selectivity coefficient of kinetic resolution can reach 371, and the method has an excellent kinetic resolution effect on various N-monosubstituted and N-unsubstituted binaphthalene diamines, H8-binaphthalene diamines and biphenyl diamines.

Enantioselective Construction of Axially Chiral Amino Sulfide Vinyl Arenes by Chiral Sulfide-Catalyzed Electrophilic Carbothiolation of Alkynes

The enantioselective construction of axially chiral compounds by electrophilic carbothiolation of alkynes is disclosed for the first time. This enantioselective transformation is enabled by the use of a Ts-protected bifunctional sulfide catalyst and Ms-protected ortho-alkynylaryl amines (Ts=tosyl; Ms=mesyl). Both electrophilic arylthiolating and electrophilic trifluoromethylthiolating reagents are suitable for this reaction. The obtained products of axially chiral vinyl–aryl amino sulfides can be easily converted into biaryl amino sulfides, biaryl amino sulfoxides, biaryl amines, vinyl–aryl amines, and other valuable difunctionalized compounds.

Organocatalytic Atroposelective Arylation of 2-Naphthylamines as a Practical Approach to Axially Chiral Biaryl Amino Alcohols

The first phosphoric acid catalyzed direct arylation of 2-naphthylamines with iminoquinones for the atroposelective synthesis of axially chiral biaryl amino alcohols has been developed. This reaction constitutes a highly functional-group-tolerant route for the rapid construction of enantioenriched axially chiral biaryl amino alcohols, and is a rare example of 2-naphthylamines acting as nucleophiles in an organocatalytic enantioselective transformation. Furthermore, the products, which feature various halogen atoms, provide access to structurally diverse axially chiral amino alcohols through further transformations.