37980-29-3

Upstream product

• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 113-00-8 guanidine nitrate 
• 668-94-0 4,5-diphenyl-1H-imidazole 
• 68212-60-2 2-amino-4,5-diphenyl-4H-imidazol-4-ol 
• 70-11-1 α-bromoacetophenone 
• 15764-47-3 2-phenylimidazo(1,2-a)pyrimidine 
• 98-86-2 acetophenone 
• 909104-02-5 2,3-diphenylimidazo[1,2-a]pyrimidine 

Downstream Products

• 80354-98-9 ethyl 6-acetyl-2,3-diphenylimidazo<1,2-a>pyrimidine-5-carboxylate 
• 82874-40-6 ethyl 3-(4,5-diphenyl-2-imidazolylamino)methylene-2,4-dioxovalerate 
• 82874-41-7 ethyl 4,5-diphenyl-2-imidazolylaminomethyleneoxaloacetate 
• 82874-60-0 5-acetyl-3-hydroxy-1-(4,5-diphenylimidazol-2-yl)-2-pyridone 
• 82874-63-3 2,3-diphenyl-5a-(1-hydroxyethyl)-4a,5a,6,7-tetrahydro-5H-cyclopropaimidazo<1,2-a>pyrimidine-4a-carboxylic acid lactone 
• 80354-99-0 ethyl 5a-acetyl-4a,5a-dihydro-2,3-diphenyl-5H-cyclopropaimidazo<1,2-a>pyrimidine-4a-carboxylate 
• 82874-62-2 ethyl 2,3-diphenyl-5a-(1-hydroxyethyl)-4a,5a,6,7-tetrahydro-5H-cyclopropaimidazo<1,2-a>pyrimidine-4a-carboxylate 
• 82874-61-1 3-acetoxy-5-acetyl-1-(4,5-diphenylimidazol-2-yl)-2-pyridone 
• 80355-00-6 ethyl 5a-acetyl-2,3-diphenyl-4a,5a,6,7-tetrahydro-5H-cyclopropaimidazo<1,2-a>pyrimidine-4a-carboxylate 
• 82874-52-0 ethyl 6-acetyl-5-chloromethyl-5,8-dihydro-2,3-diphenylimidazo<1,2-a>pyrimidine-5-carboxylate 
• 82874-55-3 ethyl 6-acetyl-8a-bromo-5-bromomethyl-2,3-diphenyl-1,5,8,8a-tetrahydroimidazo<1,2-a>pyrimidine-5-carboxylate 
• 82874-51-9 ethyl (4aR*,5aR*,6S*)-5a-Acetyl-2,3-diphenyl-6-methoxy-4a,5a,6,7-tetrahydro-5H-cyclopropaimidazo<1,2-a>pyrimidine-4a-carboxylate 
• 82874-59-7 ethyl 5-acetoxy-7-acetyl-5,6-dihydro-2,3-diphenyl-9H-imidazo<1,2-a><1,3>diazepine-5-carboxylate 
• 82874-53-1 ethyl 5-chloromethyl-6,8-diacetyl-5,8-dihydro-2,3-diphenylimidazo<1,2-a>pyrimidine-5-carboxylate 

Relevant academic research and scientific papers

Novel Combretastatin-2-aminoimidazole Analogues as Potent Tubulin Assembly Inhibitors: Exploration of Unique Pharmacophoric Impact of Bridging Skeleton and Aryl Moiety

Combretastatin A-4 (CA-4) in phosphate and serine pro-drug forms is under phase II clinical trials. With our interest of discovering CA-4 inspired new chemical entities, a novel series of 4,5-diaryl-2-aminoimidazole analogues of the compound was designed

PYRIMIDINE DERIVATIVES AND ANALOGS, PREPARATION METHOD AND USE THEREOF

This invention relates with the arylheterocycle-fused pyrimidines, derivatives and analogs of formula I: or stereoisomers, tautoers, prodrugs, pharmaceutically acceptable salts, complex salts or solvates thereof, wherein: A-cycle is of 3-8 saturated or unsaturated arylheterocycles or aliheterocyclic, containing 1-4 heteroatoms, B-cycle 5-8 member saturated or unsaturated heterocycle containing 1-4 heteroatoms; X1, X2, X3, X4 are, independently at each occurrence, C, O, S, Se, N and P elements; R1, R2, R3 is a substituent containing alicyclic group, arylcycle group, heterocyclic group, adamantane alkyl, adamantane heterocycle, adamantane analogs, sugar group, hydroxyl group, amino acid group or a combination of the above substituents. This invention also relates with their preparative methods and applications.

New Method for the Fluorimetric Determination of Guanidino Compounds with Benzoin

A new fluorimetric method for the precise and rapid determination of guanidino compounds with benzoin is described.This is based on their reaction in an aqueous potassium hydroxide solution with benzoin (dissolved in methylcellosolve), in the presence of