38201-60-4

Basic information

• Product Name: 2-MERCAPTO-5,6,7,8-TETRAHYDRO-3H-BENZO[4,5]THIENO[2,3-D]PYRIMIDIN-4-ONE
• Synonyms: 5-sulfanylidene-8-thia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7)-dien-3-one
• CAS NO: 38201-60-4
• Molecular Formula: C₁₀H₁₀N₂OS₂
• Molecular Weight: 238.33
• Mol File: 38201-60-4.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 458.6°Cat760mmHg
• Flash Point: 231.2°C
• Appearance: /
• Density: 1.51g/cm³
• Vapor Pressure: 1.35E-08mmHg at 25°C
• Refractive Index: 1.732
• CAS DataBase Reference: 2-MERCAPTO-5,6,7,8-TETRAHYDRO-3H-BENZO[4,5]THIENO[2,3-D]PYRIMIDIN-4-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-MERCAPTO-5,6,7,8-TETRAHYDRO-3H-BENZO[4,5]THIENO[2,3-D]PYRIMIDIN-4-ONE(38201-60-4)
• EPA Substance Registry System: 2-MERCAPTO-5,6,7,8-TETRAHYDRO-3H-BENZO[4,5]THIENO[2,3-D]PYRIMIDIN-4-ONE(38201-60-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 38201-60-4(Hazardous Substances Data)

Usage

General Description

2-Mercapto-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one is a chemical compound with the molecular formula C9H9N3OS. 2-MERCAPTO-5,6,7,8-TETRAHYDRO-3H-BENZO[4,5]THIENO[2,3-D]PYRIMIDIN-4-ONE is a tetrahydrobenzothiophene derivative and is often used in the synthesis of pharmaceuticals and other organic compounds. It is a potent inhibitor of protein kinases and has been studied for its potential anticancer and antiviral properties. Additionally, it has been used in the development of various drugs targeting specific diseases and conditions. Due to its unique structure and potential biological activities, this compound continues to be of interest to researchers in the fields of medicinal chemistry and drug development.

InChI:InChI=1/C10H10N2OS2/c13-8-7-5-3-1-2-4-6(5)15-9(7)12-10(14)11-8/h1-4H2,(H2,11,12,13,14)

Upstream product

• 328289-03-8 2-((ethoxycarbonylamino)carbothioyl)amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid ethyl ester 
• 4506-71-2 ethyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate 
• 333-20-0 potassium thioacyanate 
• 105544-62-5 N-(3-carboethoxy-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-N-thiourea 
• 463-71-8 thiophosgene 
• 4815-28-5 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide 
• 132167-25-0 3-(4-Ethoxy-phenyl)-4-imino-3,4,5,6,7,8-hexahydro-1H-benzo[4,5]thieno[2,3-d]pyrimidine-2-thione 
• 132424-57-8 1-(4-Chloro-phenyl)-3-(3-cyano-4,5,6,7-tetrahydro-benzo[b]thiophen-2-yl)-thiourea 
• 132167-24-9 4-Imino-3-m-tolyl-3,4,5,6,7,8-hexahydro-1H-benzo[4,5]thieno[2,3-d]pyrimidine-2-thione 
• 127749-73-9 N-phenyl-N'-[3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophene-2-yl]thiourea 
• 126105-74-6 4-Imino-3-(4-methoxy-phenyl)-3,4,5,6,7,8-hexahydro-1H-benzo[4,5]thieno[2,3-d]pyrimidine-2-thione 
• 126105-73-5 3-(4-Chloro-phenyl)-4-imino-3,4,5,6,7,8-hexahydro-1H-benzo[4,5]thieno[2,3-d]pyrimidine-2-thione 
• 126105-72-4 4-Imino-3-p-tolyl-3,4,5,6,7,8-hexahydro-1H-benzo[4,5]thieno[2,3-d]pyrimidine-2-thione 
• 126105-71-3 4-Imino-3-phenyl-3,4,5,6,7,8-hexahydro-1H-benzo[4,5]thieno[2,3-d]pyrimidine-2-thione 

Downstream Products

• 112672-69-2 (4-Oxo-3,4,5,6,7,8-hexahydro-benzo[4,5]thieno[2,3-d]pyrimidin-2-ylsulfanyl)-acetic acid 
• 1177417-36-5 3-benzoyl-1-(3-chlorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-5-one 
• 1177417-18-3 ethyl 1-(3-chlorophenyl)-5-oxo-6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-3-carboxylate 
• 1177417-22-9 ethyl 1-(4-nitrophenyl)-5-oxo-6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-3-carboxylate 
• 1177417-42-3 3-benzoyl-1-(4-nitrophenyl)-6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-5-one 
• 1177417-09-2 3-acetyl-1-(4-chlorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-5-one 
• 1177417-32-1 3-benzoyl-1-phenyl-6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-5-one 
• 1177417-38-7 3-benzoyl-1-(4-chlorophenyl)-6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-5-one 
• 1177417-30-9 1-(4-nitrophenyl)-3-(N-phenylcarbamoyl)-6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-5-one 
• 1177417-47-8 C₂₀H₁₉N₃O₃S₂ 
• 1177417-08-1 3-acetyl-1-(4-tolyl)-6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-5-one 
• 1177417-12-7 3-acetyl-1-(4-nitrophenyl)-6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-5-one 
• 1177417-40-1 3-benzoyl-1-(4-methoxyphenyl)-6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-5-one 
• 1177417-34-3 3-benzoyl-1-(4-tolyl)-6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1,2,4-triazolo[4,5-a]pyrimidin-5-one 

Relevant articles and documents

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Synthesis, characterization and biological studies of some novel thieno[2,3-d]pyrimidines

Several 2-unsubstituted thieno[2,3-d]pyrimidines have been prepared from 2-aminothiophene-3-carboxylic acid esters and their carbonitrile analogs. Some triazolothienopyrimidine and 2-thioxothienopyrimidine representatives have also been synthesized using

A facile one-pot synthesis of 6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1, 2,4-triazolo[4,5-a]pyrimidin-5-ones

The reaction of 2-mercapto-6,7,8,9-tetrahydro-3H-benzo[4,5]thieno[2,3-d] pyrimidin-4-one or its 2-methylthio derivative with hydrazonoyl halides, in the presence of triethylamine, yielded 6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]-1, 2,4-triazolo[4,5-a]pyr