383-23-3

Basic information

• Product Name: OTAVA-BB BB7011460335
• Synonyms: OTAVA-BB BB7011460335;4-(4-Fluorophenylsulfonyl)morpholine
• CAS NO: 383-23-3
• Molecular Formula: C₁₀H₁₂FNO₃S
• Molecular Weight: 245.27
• Mol File: 383-23-3.mol
• Article Data: 22

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: OTAVA-BB BB7011460335(CAS DataBase Reference)
• NIST Chemistry Reference: OTAVA-BB BB7011460335(383-23-3)
• EPA Substance Registry System: OTAVA-BB BB7011460335(383-23-3)

Safety Data

• Hazardous Substances Data: 383-23-3(Hazardous Substances Data)

Usage

General Description

OTAVA-BB BB7011460335 is a chemical compound with the molecular formula C19H23ClN2O2. It is a member of the benzazepine class of compounds and is classified as a psychoactive drug. It has been identified as a potential ligand for various receptors in the central and peripheral nervous system, including dopamine, serotonin, and adrenergic receptors. OTAVA-BB BB7011460335 may have potential applications in the treatment of neurological and psychiatric disorders, as well as in the development of new pharmaceuticals for various medical conditions. Further research and testing are needed to fully understand the potential uses and effects of OTAVA-BB BB7011460335.

Upstream product

• 1828-66-6 morpholine-4-sulfonyl chloride 
• 1765-93-1 4-fluoroboronic acid 
• 352-13-6 4-flourophenylmagnesium bromide 
• 110-91-8 morpholine 
• 23328-69-0 4-chloromorpholine 
• 459-45-0 4-fluorobenzenediazonium tetrafluoroborate 
• 371-42-6 4-Fluorothiophenol 
• 5765-65-1 4-(benzoyloxy)morpholine 
• 2905-15-9 1-fluoro-4-[(4-fluorobenzenesulfonyl)sulfanyl]benzene 
• 651-07-0 4-fluorobenzenesulfonic acid sodium salt 
• 824-80-6 sodium 4-fluorobenzenesulfinate 
• 349-88-2 4-Fluorobenzenesulfonyl chloride 

Downstream Products

• 1025712-36-0 1-cyclohexyl-6-(1-(4-(morpholinosulfonyl)phenyl)azetidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one 
• 917761-20-7 bis[4-(morpholine-4-sulfonyl)benzene]disulfide 
• 785000-58-0 N-[4-(morpholin-4-ylsulfonyl)phenyl]guanidine 
• 53915-80-3 p-(sulphonylmorpholino)phenylhydrazine 

Relevant articles and documents

S(vi) in three-component sulfonamide synthesis: Use of sulfuric chloride as a linchpin in palladium-catalyzed Suzuki-Miyaura coupling

Sulfuric chloride is used as the source of the -SO2- group in a palladium-catalyzed three-component synthesis of sulfonamides. Suzuki-Miyaura coupling between the in situ generated sulfamoyl chlorides and boronic acids gives rise to diverse sulfonamides in moderate to high yields with excellent reaction selectivity. Although this transformation is not workable for primary amines or anilines, the results show high functional group tolerance. With the solving of the desulfonylation problem and utilization of cheap and easily accessible sulfuric chloride as the source of sulfur dioxide, redox-neutral three-component synthesis of sulfonamides is first achieved. This journal is

MANUFACTURING METHOD OF COMPOUND HAVING SULFONYL GROUP

The present invention relates to a method for manufacturing a compound having a sulfonyl group, which includes a step for reacting thiosulfonates in a solvent comprising nucleophilic bases with an electrophilic agent. Accordingly, the present invention can manufacture the compound having the sulfonyl group with a variety of structures with high efficiency and high yield through more simplified processes than conventional methods.COPYRIGHT KIPO 2018

Synthesis of aromatic sulfonamides through a copper-catalyzed coupling of aryldiazonium tetrafluoroborates, DABCO·(SO2)2, and N-Chloroamines

A copper-catalyzed aminosulfonylation of aryldiazonium tetrafluoroborates, DABCO·(SO2)2, and N-chloroamines is described. This coupling reaction provides an efficient and simple approach to a wide range of sulfonamides in moderate to good yields under mild conditions. Mechanistic investigation suggests that a radical process and transition-metal catalysis are merged in this tandem reaction.