38300-04-8Relevant articles and documents
Nickel-butadiene catalytic system for the cross-coupling of bromoalkanoic acids with alkyl grignard reagents: A practical and versatile method for preparing fatty acids
Iwasaki, Takanori,Higashikawa, Kiyokazu,Reddy, Vutukuri P.,Ho, Willbe W. S.,Fujimoto, Yukari,Fukase, Koichi,Terao, Jun,Kuniyasu, Hitoshi,Kambe, Nobuaki
supporting information, p. 2956 - 2960 (2013/03/28)
The knights who say Ni: A practical and convenient synthetic route to fatty acids involves the Ni-catalyzed alkyl-alkyl cross-coupling of bromoalkanoic acids and alkyl Grignard reagents in the presence of 1,3-butadiene as an additive (see scheme). Copyright
Rigid amphiphiles for membrane protein manipulation
McQuade, D. Tyler,Quinn, Mariah A.,Yu, Seungju M.,Polans, Arthur S.,Krebs, Mark P.,Gellman, Samuel H.
, p. 758 - 761 (2007/10/03)
The two nonhomologous membrane proteins bacteriorhodopsin and bovine rhodopsin can be extracted from their native membranes by the rigid tripod amphiphile 1. Both proteins are maintained in a stable, soluble form, which is a prerequisite for crystallization. This new class of amphiphiles can be easily modified and could prove to be very useful for membrane protein manipulation.
Arylhydroxamates useful as antiallergy agents
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, (2008/06/13)
Arylhydroxamates are provided having the structure STR1 wherein R1 is hydrogen, lower alkyl, aryl, lower alkenyl, cycloalkenyl, aralkyl, or STR2 wherein n is 1 to 4 and X is hydroxy, alkoxy, amino, C1 -C4 -alkylamino or C1 -C4 -dialkylamino. R2 is hydrogen or lower alkyl; and R3 is C1 -C20 alkyl or C3 -C20 alkenyl, aryl, aryl-alkyl, cycloalkyl, aryl-alkenyl, lower alkoxy, lower alkenyloxy, aryl-alkoxy or cycloalkyloxy. These compound are useful as inhibitors of Δ5 -lipoxygenase and as such are useful as antiallergy agents.