3845-76-9

Basic information

• Product Name: N,N-Dimethylaminopropyl acrylamide
• Synonyms: (3-dimethylaminopropyl)acrylamide;3-(N,N-Dimethylaminopropyl)-acrylamide;N,N-DIMETHYLAMINOPROPYL ACRYLAMIDE (DMAPAA);N''N''DIMETYLAMINO PROPYLACRYLAMIDE;N-[3-(Dimethylamino)propyl]acrylamide (stabilized with MEHQ);acrylamido buffer pK 9.3;3-(Acryloylamino)propyldimethylamine;3-Acrylamido-N,N-dimethypropylamine
• CAS NO: 3845-76-9
• Molecular Formula: C₈H₁₆N₂O
• Molecular Weight: 156.23
• EINECS: 223-342-4
• Product Categories: monomer
• Mol File: 3845-76-9.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 142 °C / 12mmHg
• Flash Point: 140 °C
• Appearance: /solution
• Density: 0.80 g/mL at 20 °C
• Vapor Pressure: 0.00245mmHg at 25°C
• Refractive Index: 1.4800-1.4830
• Storage Temp.: 2-8°C
• PKA: 14.88±0.46(Predicted)
• Water Solubility: Completely miscible in water
• CAS DataBase Reference: N,N-Dimethylaminopropyl acrylamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-Dimethylaminopropyl acrylamide(3845-76-9)
• EPA Substance Registry System: N,N-Dimethylaminopropyl acrylamide(3845-76-9)

Safety Data

• Hazard Codes: Xi
• Statements: 10-41-67
• Safety Statements: 26-39
• RIDADR: UN 1993 3/PG 2
• WGK Germany: 1
• Hazardous Substances Data: 3845-76-9(Hazardous Substances Data)

Usage

Uses

N,N-Dimethylaminopropyl acrylamide

InChI:InChI=1/C8H16N2O/c1-4-8(11)9-6-5-7-10(2)3/h4H,1,5-7H2,2-3H3,(H,9,11)

Upstream product

• 109-55-7 1-amino-3-(dimethylamino)propane 
• 79-10-7 acrylic acid 
• 74-86-2 acetylene 
• 814-68-6 acryloyl chloride 
• 141-32-2 acrylic acid n-butyl ester 
• 52728-54-8 1,1-dimethyl-2-n-propylhydrazine 
• 21987-33-7 7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid,methyl ester 
• 292638-85-8 acrylic acid methyl ester 
• 2051-76-5 acrylic acid anhydride 
• 15519-20-7 amine 3-(dimethylamino)-1-propylamine 
• 4665-70-7 C₂₂H₂₆N₂O 
• 108-24-7 acetic anhydride 
• 74302-19-5 N-(3-dimethylaminopropyl)-3-methoxypropionamide 

Downstream Products

• 79704-35-1 carboxybetaine acrylamide 
• 80293-60-3 3-((3-acrylamidopropyl)dimethylammonio)propane-1-sulfonate 
• 109-55-7 1-amino-3-(dimethylamino)propane 
• 79-10-7 acrylic acid 

Relevant articles and documents

Method for synthesizing N,N-dimethylaminopropyl acrylamide by utilizing decarboxylation reaction

The invention discloses a method for synthesizing N,N-dimethylaminopropylacrylamide by utilizing a decarboxylation reaction. The method is characterized by comprising the following steps: dropwisely adding 3-dimethylaminopropylamine into a mixed solution of maleic anhydride and a solvent, stirring, reacting to obtain an intermediate, adding catalysts DMAP and DCC into the intermediate, reacting to produce Barton ester, adding a catalytic amount of tributyltin, AIBN and a polymerization inhibitor, carrying out a reaction to remove one molecule of CO2, and carrying out reduced pressure distillation to obtain a high-purity product. According to the invention, a low-temperature reaction route is used, reaction conditions are mild, and production is safer.

Method for synthesizing acrylamide derivative

The invention relates to a method for synthesizing an acrylamide derivative from alkyl primary amine and acrylamide as raw materials and belongs to the field of chemical product synthesis methods. Themethod for synthesizing the acrylamide derivative comprises the following steps: 1) under conditions of 150-160 DEG C and 0.6-1MPa, conducting a Diels-Alder reaction on acrylamide and anthracene so as to obtain an acrylamide addition intermediate of 1:1; 2) conducting backflowing on the addition intermediate, alkyl primary amine and a catalyst for 6-20 hours at 50-180 DEG C, and conducting an amino exchange reaction so as to obtain an acrylamide derivative addition intermediate; and 3) carrying out thermal cracking on the acrylamide derivative addition intermediate at 150-180 DEG C and 1-3kPa, conducting rectification so as to obtain an acrylamide derivative, conducting sublimation recycling on anthracene, and repeating the process. The method for synthesizing the acrylamide derivative, which is provided by the invention, is free of liquid solvent, is capable of effectively reducing the content of VOCs (volatile organic compounds) in the generation process, and is simple in reaction process, easy in product and recycling raw material separation, easy in reaction condition control, high in security, high in reaction yield, small in byproduct amount, simple in aftertreatment, high in product purity and easy in industrial production.

Preparation method of single-functionality or multi-functionality acrylamide type compounds

The present invention relates to the field of new material fine chemicals, particularly to a new mild, efficient and economical preparation process technology of a class of single-functionality or multi-functionality acrylamide type compounds, wherein the materials are important alkene-containing unsaturated compounds, and are increasingly used in radiation polymerization curing materials or medical application materials and other fields.