38452-47-0

Basic information

• Product Name: 1,2-DICHLORO-4-(METHYLSULFONYL)BENZENE
• Synonyms: 1,2-DICHLORO-4-(METHYLSULFONYL)BENZENE;1,2-DICHLORO-4-(METHYLSULPHONYL)BENZENE;3,4-DICHLOROPHENYLMETHYLSULFONE;3,4-Dichloro-1-(methylsulfonyl)benzene;Benzene, 1,2-dichloro-4-(Methylsulfonyl)-
• CAS NO: 38452-47-0
• Molecular Formula: C₇H₆Cl₂O₂S
• Molecular Weight: 225.09
• EINECS: 253-942-1
• Product Categories: blocks;Sulfonamides
• Mol File: 38452-47-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 109-110
• Boiling Point: 371.3°C at 760 mmHg
• Flash Point: 178.3°C
• Appearance: /
• Density: 1.451g/cm³
• Vapor Pressure: 2.23E-05mmHg at 25°C
• Refractive Index: 1.555
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1,2-DICHLORO-4-(METHYLSULFONYL)BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-DICHLORO-4-(METHYLSULFONYL)BENZENE(38452-47-0)
• EPA Substance Registry System: 1,2-DICHLORO-4-(METHYLSULFONYL)BENZENE(38452-47-0)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 38452-47-0(Hazardous Substances Data)

Usage

General Description

1,2-Dichloro-4-(methylsulfonyl)benzene, also known as CID247690, is a synthetic compound characterized by a benzene ring with two chlorine atoms and a methylsulfonyl group attached to it. The methyl sulfonyl group has a sulfur atom joined to an oxygen atom and a methyl group. 1,2-DICHLORO-4-(METHYLSULFONYL)BENZENE is generally subjected to further reactions to yield other significant compounds in organic chemistry due to its reactivity. Though it is lesser-known, it is generally associated with chemical and industrial applications. Its specific information regarding toxicity, health effects, or environmental impact is not readily available, indicating it might not be widely used or its effects not comprehensively studied.

InChI:InChI=1/C7H6Cl2O2S/c1-12(10,11)5-2-3-6(8)7(9)4-5/h2-4H,1H3

Upstream product

• 95-50-1 1,2-dichloro-benzene 
• 7143-01-3 Methanesulfonic anhydride 
• 67141-36-0 sodium 3,4-dichlorobenzenethiolate 
• 124-63-0 methanesulfonyl chloride 
• 17733-23-2 methyl 3,4-dichlorophenyl sulfide 

Downstream Products

• 67646-65-5 methyl-pentachlorophenyl sulfone 
• 13244-35-4 2-chloro-4-(methylsulfonyl)aniline 
• 20945-65-7 2-chloro-4-methanesulfonyl-phenol 

Relevant articles and documents

Highly atom-economic, catalyst- and solvent-free oxidation of sulfides into sulfones using 30% aqueous H2O2

Highly atom-efficient oxidation of sulfides into sulfones under solvent- and catalyst-free reaction conditions using a 30% aqueous solution of H 2O2 at 75 °C is reported. A structurally diverse set of phenyl alkyl-, phenyl benzyl-, benzyl alkyl-, dialkyl-, heteroaryl alkyl- and cyclic sulfides were transformed into sulfones regardless of the aggregate state and electronic nature of the substituents. In spite of the heterogeneous reaction mixtures throughout the work, no difficulties with stirring and reaction progress were noted. In numerous cases, only 10 mol% excess of H 2O2 was used, thus contributing considerably to the high atom economy of the process. Some solid substrates required a variable excess of hydrogen peroxide; however, the reactions were performed strictly without organic solvents. The transformation was demonstrated to be amenable for scale-up with both liquid and solid sulfides. In addition, isolation and purification of the crude products can be simply done with only filtration and crystallization.

Methanesulfonylation of deactivated aromatics with superelectrophilic CH3so2F·3SbF5 and (CH3so2)2O-2CF3so 3H/B(O3SCF3)3 systems

Methanesulfonylation of various deactivated arenes, including tri- and tetrafluorobenzenes, was achieved in good yield under mild conditions using superelectrophilic CH3SO2F/3SbF5 and (CH3SO2O)2O/2CF3SO 3H-B(O3SCF3)3 reagent systems. 1998 MAHK "Hayka/Interperiodica".