38452-47-0

Usage

Uses

Used in Chemical Synthesis:
1,2-DICHLORO-4-(METHYLSULFONYL)BENZENE is used as a synthetic intermediate for the production of various organic compounds. Its reactivity allows it to be a key component in the synthesis of a range of chemical products, contributing to the development of new materials and compounds in the field of organic chemistry.
Used in Industrial Applications:
1,2-DICHLORO-4-(METHYLSULFONYL)BENZENE is used as a chemical intermediate in industrial processes. Its role in the production of other significant compounds makes it a valuable resource in the chemical industry, where it can be utilized to create a variety of products with different applications and functions.

InChI:InChI=1/C7H6Cl2O2S/c1-12(10,11)5-2-3-6(8)7(9)4-5/h2-4H,1H3

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 95-50-1 1,2-dichloro-benzene 
• 67141-36-0 sodium 3,4-dichlorobenzenethiolate 
• 7143-01-3 Methanesulfonic anhydride 
• 17733-23-2 methyl 3,4-dichlorophenyl sulfide 

Downstream Products

• 67646-65-5 methyl-pentachlorophenyl sulfone 
• 13244-35-4 2-chloro-4-(methylsulfonyl)aniline 
• 20945-65-7 2-chloro-4-methanesulfonyl-phenol 

Relevant academic research and scientific papers

Highly atom-economic, catalyst- and solvent-free oxidation of sulfides into sulfones using 30% aqueous H2O2

Highly atom-efficient oxidation of sulfides into sulfones under solvent- and catalyst-free reaction conditions using a 30% aqueous solution of H 2O2 at 75 °C is reported. A structurally diverse set of phenyl alkyl-, phenyl benzyl-, benzyl alkyl-, dialkyl-, heteroaryl alkyl- and cyclic sulfides were transformed into sulfones regardless of the aggregate state and electronic nature of the substituents. In spite of the heterogeneous reaction mixtures throughout the work, no difficulties with stirring and reaction progress were noted. In numerous cases, only 10 mol% excess of H 2O2 was used, thus contributing considerably to the high atom economy of the process. Some solid substrates required a variable excess of hydrogen peroxide; however, the reactions were performed strictly without organic solvents. The transformation was demonstrated to be amenable for scale-up with both liquid and solid sulfides. In addition, isolation and purification of the crude products can be simply done with only filtration and crystallization.

Total Synergistic effect between triflic acid and bismuth(IIIr antimony(III) chlorides in catalysis of the Methanesulfonylation of Arenes

A total synergistic effect between bismuth(III) or antimony(III) chlorides and triflic acid has been observed in the Friedel-Crafts methanesulfonylation of arenes and has resulted in the development of the first efficient catalytic systems usable for the methanesulfonylation of both activated and deactivated arenes. A proposed mechanism to explain the observed effects is also discussed. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

Methanesulfonylation of deactivated aromatics with superelectrophilic CH3so2F·3SbF5 and (CH3so2)2O-2CF3so 3H/B(O3SCF3)3 systems

Methanesulfonylation of various deactivated arenes, including tri- and tetrafluorobenzenes, was achieved in good yield under mild conditions using superelectrophilic CH3SO2F/3SbF5 and (CH3SO2O)2O/2CF3SO 3H-B(O3SCF3)3 reagent systems. 1998 MAHK "Hayka/Interperiodica".