38459-72-2

Upstream product

• 623-05-2 (4-hydroxyphenyl)methanol 
• 106-93-4 ethylene dibromide 
• 52191-15-8 4-(2-bromoethyloxy)benzaldehyde 
• 123-08-0 4-hydroxy-benzaldehyde 
• 56850-91-0 methyl 4-(2-bromoethoxy)benzoate 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 107-04-0 1-Bromo-2-chloroethane 

Downstream Products

• 223251-16-9 [4-(2-hexamethyleneimino-1-yl-ethoxy)-phenyl]-methanol 
• 131028-54-1 (4-(2-(dimethylamino)ethoxy)phenyl)methanol 
• 952481-09-3 acetic acid 4-(2-bromoethoxy)benzyl ester 
• 952481-11-7 3-[4-(2-bromoethoxy)phenyl]-2-methylpropionic acid methyl ester 
• 952481-12-8 C₁₄H₁₉BrO₃ 
• 952481-13-9 3-{4-[2-(N-nonyl-N-pyridin-2-ylamino)ethoxy]phenyl}-2-methylpropanoic acid methyl ester 
• 952481-14-0 3-{4-[2-(N-nonyl-N-pyridin-2-ylamino)ethoxy]phenyl}-2,2-dimethylpropanoic acid methyl ester 
• 902767-81-1 2-bromo-1-(4-((5,6-dichloronaphthyloxy)methyl)phenoxy)ethane 
• 54063-52-4 2-methoxycarbonyl-4'-(2-piperidinoethyloxy)benzophenone 
• 109098-67-1 4-(2-bromoethoxy)benzyl chloride 
• 212771-30-7 1-[2-(4-chloromethylphenoxy)ethyl]perhydroazepin 

Relevant academic research and scientific papers

A New Chiral Cyclophane Derived from 1,1'-Binaphthol and Benzylviologen

A new chiral cyclophane, with a binding cavity defined by the 1,1'-binaphthyl "minor groove" and a strongly ?-accepting 4,4'-bipyridinium dication, has been synthesized.It self-associates in solution (K=(4.1+/-1.6)*102 M-1), and forms charge-transfer complexes with strong ?-electron donors.

HYPOXANTHINE COMPOUND

PROBLEM TO BE SOLVED: To provide a novel compound having an inhibitory action of prolyl hydroxylase (PHDs) and useful as a therapeutic agent of an inflammatory bowel disease such as ulcerative colitis. SOLUTION: The present invention relates to a hypoxanthine compound represented by the following formula (I) or a pharmacologically acceptable salt thereof. The compound of the present invention or its pharmaceutically acceptable salt has an inhibitory effect of prolyl hydroxylase and is useful as a therapeutic agent for inflammatory bowel disease such as ulcerative colitis. SELECTED DRAWING: None COPYRIGHT: (C)2021,JPOandINPIT

Design, synthesis, in silico and in vitro studies for new nitric oxide‐releasing indomethacin derivatives with 1,3,4‐oxadiazole‐2‐thiol scaffold

Starting from indomethacin (IND), one of the most prescribed non‐steroidal anti‐inflammatory drugs (NSAIDs), new nitric oxide‐releasing indomethacin derivatives with 1,3,4‐oxadiazole‐ 2‐thiol scaffold (NO‐IND‐OXDs, 8a‐p) have been developed as a safer and

Preparation method and application of naphthylamine compounds and salts thereof

The invention discloses a preparation method and application of naphthylamine compounds and salts thereof, concretely provides a method for synthesizing the naphthylamine compounds by taking 4-formylphenol as a substrate, and also provides a preparation m

Naphthylamine compound and biologically acceptable salt thereof as well as preparation method and application thereof

Aiming at shortage of anti-cancer targeting medicines in the prior art, the invention provides a naphthylamine compound and a biologically acceptable salt thereof as well as a preparation method and application thereof. By adopting the naphthylamine compo

USE OF DISUBSTITUTED BENZENES TO CONTROL INSECTICIDE-RESISTANT PESTS

The invention is in the technical field of insect control and relates to the use of a disubstituted benzenes for controlling insecticide-resistant pests such as mosquitoes and cockroaches.

PHENYL BENZYL ETHER DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF

Parts of compounds, after being labeled by radionuclide, of the phenyl benzyl ether derivative, are used as Aβ plaque imaging agent. The structural formula of the phenyl benzyl ether derivative is shown by formula (I). The present invention develops a kin

Synthesis and evaluation of 2-nonylaminopyridine derivatives as PPAR ligands

To find novel PPAR ligands, we prepared several 3-{3 or 4-[2-(nonylpyridin-2-ylamino)ethoxy]phenyl}-propanoic acid derivatives which were designed based on the structure of our previous PPARγ ligand 1. In PPAR binding affinity assays, compound 4, which ha

INSECTICIDAL HETEROCYCLIC 1,4-DISUBSTITUTED BENZENE N-OXIDES

Certain novel heterocyclic 1,4-disubstituted benzene N-oxide derivatives have provided unexpected insecticidal and acaricidal activity. These compounds are represented by formula (I) wherein R1, R2, B, D, T, U, m, and n are fully des

Benzothieno[3,2-b]indole derivatives as potent selective estrogen receptor modulators

A series of estrogen receptor ligands based on benzothieno[3,2-b]indole were synthesized and their binding affinity for estrogen receptor subtypes (ERα and ERβ) and effects on mouse uterus and bone were evaluated. Some of these compounds showed strong bin