38503-22-9Relevant academic research and scientific papers
Chiral Macrocyclic Organocatalysts for Kinetic Resolution of Disubstituted Epoxides with Carbon Dioxide
Ema, Tadashi,Yokoyama, Maki,Watanabe, Sagiri,Sasaki, Sota,Ota, Hiromi,Takaishi, Kazuto
supporting information, p. 4070 - 4073 (2017/08/15)
Among chiral macrocycles 1 synthesized, 1m with the 3,5-bis(trifluoromethyl)phenylethynyl group was the best organocatalyst for the enantioselective synthesis of cyclic carbonates from disubstituted or monosubstituted epoxides and CO2. The X-ray crystal structure of 1m revealed a well-defined chiral cavity with multiple hydrogen-bonding sites that is suitable for the enantioselective activation of epoxides. A catalytic cycle proposed was supported by DFT calculations.
A new synthesis of trans-2,3-diaryloxiranes and 2-(1 H -benzo[ d ][1,2,3]-triazol-1-yl)-1-arylethanols via the reactions of 1-benzyl-3- methylbenzo-triazolium ylide with aryl aldehydes
Xiao, Xiaohui,Lin, Daqin,Tong, Shuitian,Mo, Hailan
experimental part, p. 2823 - 2826 (2011/12/21)
1-Benzyl-3-methylbenzotriazolium ylide was formed by the reaction of 1-benzyl-3-methylbenzotriazolium iodide with t-BuOK. Subsequently it reacted with various aryl aldehydes to give the corresponding trans-2,3-diaryloxiranes and 2-(1H-benzo-[d][1,2,3]triazol-1-yl)-1-arylethanols in moderate to high yields. Georg Thieme Verlag Stuttgart · New York.
