90151-40-9

Basic information

• Product Name: Benzaldehyde, 4-amino-3-methoxy- (9CI)
• Synonyms: Benzaldehyde, 4-amino-3-methoxy- (9CI);Benzaldehyde,4-amino-3-methoxy-(9Cl);4-AMino-3-Methoxy-benzaldehyde
• CAS NO: 90151-40-9
• Molecular Formula: C₈H₉NO₂
• Molecular Weight: 151.16256
• Product Categories: ALDEHYDE
• Mol File: 90151-40-9.mol
• Article Data: 8

Chemical Properties

• Melting Point: 100 °C
• Boiling Point: 310.7°C at 760 mmHg
• Flash Point: 175.3°C
• Appearance: /
• Density: 1.186g/cm³
• Vapor Pressure: 0.000589mmHg at 25°C
• Refractive Index: 1.605
• PKA: 1.81±0.10(Predicted)
• CAS DataBase Reference: Benzaldehyde, 4-amino-3-methoxy- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 4-amino-3-methoxy- (9CI)(90151-40-9)
• EPA Substance Registry System: Benzaldehyde, 4-amino-3-methoxy- (9CI)(90151-40-9)

Safety Data

• Hazardous Substances Data: 90151-40-9(Hazardous Substances Data)

Usage

General Description

4-Amino-3-methoxy-Benzaldehyde, also referred to as in the 9th Collective Index (9CI) of chemical substances, is an organic compound containing an amino group (-NH2) and a methoxy group (-OCH3) attached to a benzaldehyde core structure. This structure consists of a benzene ring with an attached formyl functional group (-CHO). As its structure suggests, it includes elements like carbon, hydrogen, nitrogen, and oxygen. Its potential uses could be in the research and development of pharmaceuticals and other organic compounds. As with any compound, its toxicity and safety measures need to be properly evaluated, and it should be handled according to material safety guidelines.

InChI:InChI=1/C8H9NO2/c1-11-8-4-6(5-10)2-3-7(8)9/h2-5H,9H2,1H3

Upstream product

• 80410-57-7 3-methoxy-4-nitrobenzaldehyde 
• 50-00-0 formaldehyd 
• 90-04-0 2-methoxy-phenylamine 
• 38512-82-2 3-methoxy-4-nitrotoluene 
• 41608-64-4 methyl 3-methoxy-4-aminobenzoate 
• 148459-54-5 (4-amino-3-methoxyphenyl)methanol 
• 704-13-2 5-formyl-2-nitrophenol 
• 128495-46-5 4-fluoro-3-methoxybenzaldehyde 
• 2486-69-3 3-methoxy-4-aminobenzoic acid 
• 61066-33-9 pyrimidine-2,4,5,6(1H,3H)-tetraone 

Downstream Products

• 121-33-5 vanillin 
• 90922-26-2 4-Acetamido-3-methoxybenzaldehyde 
• 1030-22-4 1,2-bis(4-cyanophenyl)diazene oxide 
• 43192-34-3 4-bromo-3-methoxybenzaldehyde 
• 1177015-72-3 1-bromo-2-methoxy-4-((E)-2-nitro-vinyl)-benzene 
• 113081-51-9 2-(4-bromo-3-methoxy-phenyl)-ethylamine 
• 1428796-73-9 N-(4-bromo-3-methoxyphenethyl)acetamide 
• 1428796-74-0 7-bromo-6-methoxy-1-methyl-3,4-dihydroisoquinoline 
• 1428796-75-1 ethyl 9-bromo-8-methoxy-5,6-dihydropyrrolo[2,1-a]isoquinoline-2-carboxylate 
• 1428796-76-2 ethyl 8-methoxy-9-(pyridin-3-yl)-5,6-dihydropyrrolo[2,1-a]isoquinoline-2-carboxylate 
• 1428796-77-3 8-methoxy-9-(pyridin-3-yl)-5,6-dihydropyrrolo[2,1-a]isoquinoline-2-carboxylic acid 
• 1428796-78-4 (R)-N-(1-(tert-butyldimethylsilyloxy)-3-(1H-indol-3-yl)propan-2-yl)-8-methoxy-9-(pyridin-3-yl)-5,6-dihydropyrrolo[2,1-a]isoquinoline-2-carboxamide 
• 1428796-07-9 (R)-3-(3-fluorophenyl)-N-(1-hydroxy-3-(1H-indol-3-yl)propan-2-yl)-8-methoxy-9-(pyridin-3-yl)-5,6-dihydropyrrolo[2,1-a]isoquinoline-2-carboxamide 
• 1428796-79-5 ethyl 8-methoxy-9-vinyl-5,6-dihydropyrrolo[2,1-a]isoquinoline-2-carboxylate 

Relevant articles and documents

Nucleophilic aromatic substitution of unactivated fluoroarenes enabled by organic photoredox catalysis

Nucleophilic aromatic substitution (SNAr) is a classical reaction with well-known reactivity toward electron-poor fluoroarenes. However, electron-neutral and electron-rich fluoro(hetero)arenes are considerably underrepresented. Herein, we present a method for the nucleophilic defluorination of unactivated fluoroarenes enabled by cation radical-accelerated nucleophilic aromatic substitution. The use of organic photoredox catalysis renders this method operationally simple under mild conditions and is amenable to various nucleophile classes, including azoles, amines, and carboxylic acids. Select fluorinated heterocycles can be functionalized using this method. In addition, the late-stage functionalization of pharmaceuticals is also presented. Computational studies demonstrate that the site selectivity of the reaction is dictated by arene electronics.

FSH RECEPTOR ANTAGONISTS

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(DIHYDRO) IMIDAZOISO (5, 1-A) QUINOLINES AS FSH RECEPTOR AGONISTS FOR THE TREATMENT OF FERTILITY DISORDERS

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