38765-81-0

Upstream product

• 3607-48-5 iodine isocyanate 
• 110-83-8 cyclohexene 
• 3315-16-0 silver cyanate 
• 917-61-3 sodium isocyanate 

Downstream Products

• 136863-89-3 N-(trans-2-iodocyclohexyl)-N'-(β-D-ribopyranosyl)urea 
• 136863-89-3 N-(trans-2-iodocyclohexyl)-N'-(β-D-xylopyranosyl)urea 
• 135103-95-6 N-Benzyl-N-methyl-N'-(trans-2-iodocyclohexyl)urea 
• 1121-57-9 1-isocyanocyclohexene 
• 1199-15-1 methyl trans-N-(2-iodocyclohexyl)carbamate 
• 89868-71-3 (+/-)-((3ar,7ac)-3a,4,5,6,7,7a-hexahydro-benzoxazol-2-yl)-phenyl-amine 
• 136863-95-1 N-(trans-2-iodocyclohexyl)-N'-(2,3,4,6-tetra-O-acetyl-β-glucopyranosyl)urea 
• 136863-96-2 N-(trans-2-iodocyclohexyl)-N'-(2,3,4-tri-O-acetyl-β-D-xylopyranosyl)urea 
• 136864-01-2 2-(p-bromophenylamino)-cis-3a,4,5,6,7,7a-hexahydrobenzoxazole 
• 136863-92-8 N-(p-bromophenyl)-N'-(trans-2-iodocyclohexyl)urea 
• 135103-94-5 N-(n-Butyl)-N'-(trans-2-iodocyclohexyl)urea 

Relevant academic research and scientific papers

Conformationally constrained serotonin analogues: Stereoselective synthesis of trans-3-(2-aminocycloalkyl)indoles by aziridine ring opening

Trans-3-(2-aminocyclopentyl)indoles 9a,c and trans-3-(2-aminocyclohexyl)indoles 9b,d have been stereoselectively prepared by nucleophilic ring opening reaction of N-Boc cycloalkylaziridines 6a,b and the 'lower order' magnesium cuprate II, generated from the corresponding indolilmagensium bromides derived from 7a,b.

Stereoselective synthesis of 1,3,4-substituted tetrahydro-β-carbolines from indoles based on selective transformations

1, 3, 4-Substituted tetrahydro β-carbolines 4 have been prepared from indoles 6 by two selective transformations: first, nucleophilic aziridine ring opening with a lower order indolyl magnesium cuprate obtaining the α,β-substituted tryptamines 5 and secondly, a 'Pictet-Spengler-like' reaction between azalactones 12 and tryptamines 5. Under the acidic reaction conditions used, the thermodynamically favoured tetrahydro β-carbolines 4 are obtained due to the conformational restrictions imposed by the tryptamine substituents.

A Convenient Preparation of vic-Iodo-Isocyanates

vic-Iodo-isocyanates are conveniently prepared by treatment of alkenes with iodine/thallium(I) cyanate or with iodine(I) chloride/thallium(I) cyanate.Treatment of the phenylurea (5) with silver perchlorate or m-chloroperbenzoic acid gives the oxazoline (2