38833-34-0Relevant academic research and scientific papers
Unusual structural features in the lysozyme derivative of the tetrakis(acetato)chloridodiruthenium(ii,iii) complex
Messori, Luigi,Marzo, Tiziano,Sanches, Rute Nazare Fernandes,Hanif-Ur-Rehman,De Oliveira Silva, Denise,Merlino, Antonello
, p. 6172 - 6175 (2014)
The reaction between the paddle-wheel tetrakis(acetato) chloridodiruthenium(II,III) complex, [Ru2(μ-O2CCH 3)4Cl] and hen egg-white lysozyme (HEWL) was investigated through ESI-MS and UV/Vis spectroscopy and the formation of a stable metal-protein adduct was unambiguously demonstrated. Remarkably, the diruthenium core is conserved in the adduct while two of the four acetate ligands are released. The crystal structure of this diruthenium-protein derivative was subsequently solved through X-ray diffraction analysis to 2.1 A resolution. The structural data are in agreement with the solution results. It was found that HEWL binds two diruthenium moieties, at Asp101 and Asp119, respectively, with the concomitant release of two acetate ligands from each diruthenium center.
The Origins of Stereoselectivities in Olefin Metathesis
Hamilton, James G.,Ivin, Kenneth J.,McCann, G. Malachy,Rooney, John J.
, p. 1379 - 1381 (1984)
A detailed study of the microstructures of ring-opened polymers of norbornene and several methyl derivatives, using salts of Ru and Os as catalysts, shows that the widely noted stereoselective feature of cis giving cis and trans giving trans in olefin metathesis is attributable to different forms of metallacarbene propagating species rather than to different configurations of putative metallacyclobutanes derivable from the same metallacarbene.
