39055-84-0

Usage

Uses

Used in Pharmaceutical Industry:
4-CHLORO-4'-NITRODIPHENYL SULPHONE is used as an immune adjuvant for enhancing the body's immune response to vaccines and other immunogenic substances. Its chemical structure allows it to stimulate the immune system, leading to increased production of antibodies and improved overall immune response.
Used in Chemical Industry:
In the chemical industry, 4-CHLORO-4'-NITRODIPHENYL SULPHONE can be utilized as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure and reactivity make it a valuable building block for the development of new compounds with specific applications and properties.

Upstream product

• 89-64-5 p-chloro-o-nitrophenol 
• 106-54-7 p-Chlorothiophenol 
• 1948-92-1 4-(4-nitrophenylsulfonyl)aniline 
• 21969-11-9 1-(4-chlorophenylthio)-4-nitrobenzene 
• 636-98-6 p-nitrobenzene iodide 
• 14752-66-0 sodium p-chlorobenzenesulphinate 

Downstream Products

• 39066-28-9 5-p-chlorobenzenesulphonylsalicylonitrile 
• 100-32-3 di(p-nitrophenyl) disulfide 
• 77853-04-4 4-Chloro-benzenethiosulfonic acid; compound with ammonia 
• 100-01-6 4-nitro-aniline 
• 952-97-6 4-nitrophenyl phenyl sulfide 
• 101533-57-7 4-(4-aminobenzenesulfonyl)benzonitrile 
• 565-23-1 1-chloro-4-((4-fluorophenyl)sulfonyl)benzene 
• 7146-68-1 4-(4-chloro-benzenesulfonyl)-aniline 
• 350-46-9 4-Fluoronitrobenzene 

Relevant academic research and scientific papers

Optimization of a urea-containing series of nicotinamide phosphoribosyltransferase (NAMPT) activators

NAD+ is a crucial cellular factor that plays multifaceted roles in wide ranging biological processes. Low levels of NAD+ have been linked to numerous diseases including metabolic disorders, cardiovascular disease, neurodegeneration,

Oxidation of Aryl Sulfides to Sulfones with Alumina-Supported Ruthenium Catalyst in Dimethyl Carbonate-Water Media

A new procedure for the oxidation of sulfides to sulfones utilizing heterogeneous ruthenium reagent has been developed. A small amount of ruthenium trichloride (RuCl3) supported on alumina and excess sodium metaperiodate (NaIO4) was used to produce the ruthenium oxidizing catalyst in the reaction mixture. Sodium metaperiodate oxidized the pre-catalyst RuCl3 to RuO4 and also maintained a constant supply of RuO4 by oxidizing lower valent ruthenium ions during the course of the reaction. An environmentally friendly solvent mixture of dimethyl carbonate (DMC) and water was employed. A wide variety of aromatic sulfides were oxidized to sulfones in good to excellent yields by utilizing this procedure.

Metal and solvent free selective oxidation of sulfides to sulfone using bifunctional ionic liquid [pmim]IO4

The oxidation of organo-sulfides to sulfones has been accomplished using an easily accessible bifunctional ionic liquid, [pmim]IO4 in the absence of any other oxidants, metal and organic solvent at ambient temperature. A variety of sulfides including dialkyl, aryl-alkyl, diaryl, and aryl-hetero aryl have been oxidized to the corresponding functionalized sulfones in high yields by this procedure.

A highly active and easily recoverable chitosan@copper catalyst for the C-S coupling and its application in the synthesis of zolimidine

Aryl sulfones were synthesized using a highly active and easily recoverable heterogeneous Cu catalyst which was prepared by simply stirring an aqueous suspension of chitosan in water with copper salts. The chitosan@copper catalyst catalyzed the coupling reactions of aryl halides with sodium sulfinates to readily give the corresponding sulfones in good to excellent yields. The highly active catalyst can be reused many times without losing its catalytic activity. In addition, by using this protocol, the marketed drug zolimidine (antiulcer) could be synthesized easily. This journal is the Partner Organisations 2014.

QUINOLINE DERIVATIVE AND INSECTICIDE CONTAINING SAME AS ACTIVE CONSTITUENT

Disclosed are compounds that have excellent insecticidal activity and are usable as agricultural and horticultural insecticides. Compounds represented by formula (I) or agriculturally and horticulturally acceptable acid addition salts thereof have excellent insecticidal activity and are usable as agricultural and horticultural insecticides.

QUINOLINE DERIVATIVE AND INSECTICIDE CONTAINING SAME AS ACTIVE CONSTITUENT

Disclosed is a compound having excellent insecticidal activity and usable as an insecticide for agricultural and horticultural use. A compound represented by the formula (I) below and an agriculturally and horticulturally acceptable acid addition salt thereof have excellent insecticidal activity and can be used as an insecticide for agricultural and horticultural use.