39138-90-4

Usage

InChI:InChI=1/C12H9NO4/c14-11-3-1-2-4-12(11)17-10-7-5-9(6-8-10)13(15)16/h1-8,14H

Upstream product

• 32795-85-0 2-methoxyphenyl 4'-nitrophenyl ether 
• 108-95-2 phenol 
• 5633-98-7 potassium guaiacolate 
• 120-80-9 benzene-1,2-diol 
• 350-46-9 4-Fluoronitrobenzene 
• 100-02-7 4-nitro-phenol 
• 100-00-5 4-chlorobenzonitrile 
• 18826-89-6 2,4-Di-tert-butyl-6-(4-nitro-phenoxy)-phenol 

Downstream Products

• 36859-45-7 4-chloro-2-(4-nitro-phenoxy)-phenol 
• 103790-53-0 2-(4-Amino-phenoxy)-phenol 
• 84604-85-3 4-bromo-2-(4-nitro-phenoxy)-phenol 
• 84604-84-2 4,5-dibromo-2-(4-nitro-phenoxy)-phenol 
• 36859-56-0 4,5-dichloro-2-(4-nitro-phenoxy)-phenol 

Relevant academic research and scientific papers

Metal-free oxidative aromatization of 2-aryloxycyclohex-2-en-1-ones to 2-aryloxyphenols using DDQ/Amberlyst-15

Efficient metal-free oxidative aromatization of 2-aryloxycyclohex-2-en-1-ones was achieved by a combination of 2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ) and Amberlyst-15. The conditions for oxidative aromatization are mild and applicable for a variety of substrates, and Amberlyst-15 can be successfully recovered and recycled.

Efficient method for demethylation of aryl methyl ether using aliquat-336

A rapid method for selective cleavage of aryl methylethers can be achieved in the presence of a protic acid and a catalytic amount of phase-transfer catalyst (Aliquat-336). Aliquat-336 accelerates the rate of reaction and affords the corresponding phenols in excellent to good yields on a wide variety of substrates. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications for the following free supplemental resource(s): Full experimental and spectral details.]

Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders

Disclosed are pyrrolopyridazine compounds, methods of preparing such compounds, and their use for the treatment of proliferative, inflammatory, and other disorders.

PHENOXENIUM IONS. IDENTICAL INTERMEDIATES IN THE ACID-CATALYZED SOLVOLYSIS OF N-TOSYL-O-ARYLHYDROXYLAMINES AND IN THE THERMOLYSIS OF N-ARYLOXYPYRIDINIUM SALTS

The acid-catalyzed solvolysis of N-tosyl-O-arylhydroxylamines in aromatic solvents and the thermolysis of N-aryloxypyridinium salts involve common intermediates, phenoxenium ions, for the formation of hydroxybiphenyl derivatives.Diphenylethers are formed when the heterolysis of the N-O bonds is slow and the aromatic solvent has high nucleophilicity.

Cyclodienones. X. Reaction of Halo-cyclohexadien-1-ones with Phenols in the Presence of α-Picoline and Preparation of 4-Hydroxy- and 2-Hydroxyphenyl Aryl Ethers

Reaction of 4-halocyclohexadienones such as 4-bromo-(1a), 4-chloro-2,4,6-tri-t-butyl-(1b), 2,4-dichloro-4,6-di-t-butyl-2,5-cyclohexadien-1-one, and 2,4-dichloro-2,6-di-t-butyl-3,5-cyclohexadien-1-one with phenols in the presence of α-picoline was carried out under various conditions.The reaction of 1a and 1b with phenols afforded the corresponding 2-aryloxy-4,6-di-t-butyl phenols together with various by-products.The AlCl3 catalyzed trans-t-butylation of 2-aroxy-4,6-di-t-butyl-phenols, which were obtained by the above reaction, afforded the corresponding 2-hydroxyphenyl aryl ethers.The similar reaction of 4-aroxy-2,4,6-tri-t-butyl-2,5-cyclohexadien-1-ones also afforded the corresponding 4-hydroxyphenyl aryl ethers.