6318-20-3

Basic information

• Product Name: 4-ACETOXY-3,5-DIMETHOXYBENZOIC ACID
• Synonyms: 4-ACETOXY-3,5-DIMETHOXYBENZOIC ACID;ACETYL SYRINGIC ACID;RARECHEM AL BE 0701;TIMTEC-BB SBB000792;4-ACETOXY-3,5-DIMETHOXY BENZOIC ACID, ACETYL SYRINGIC ACID;4-(Acetyloxy)-3,5-dimethoxy-benzoic acid
• CAS NO: 6318-20-3
• Molecular Formula: C₁₁H₁₂O₆
• Molecular Weight: 240.21
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 6318-20-3.mol
• Article Data: 24

Chemical Properties

• Melting Point: 190-191°C
• Boiling Point: 338.9°C at 760 mmHg
• Flash Point: 127.4°C
• Appearance: /
• Density: 1.28g/cm³
• Vapor Pressure: 3.7E-05mmHg at 25°C
• Refractive Index: 1.529
• CAS DataBase Reference: 4-ACETOXY-3,5-DIMETHOXYBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ACETOXY-3,5-DIMETHOXYBENZOIC ACID(6318-20-3)
• EPA Substance Registry System: 4-ACETOXY-3,5-DIMETHOXYBENZOIC ACID(6318-20-3)

Safety Data

• Hazardous Substances Data: 6318-20-3(Hazardous Substances Data)

Usage

General Description

4-Acetoxy-3,5-dimethoxybenzoic acid, also known as acetylsalicylic acid, is a chemical compound with the molecular formula C11H12O4. It is a derivative of salicylic acid and is commonly used as a pain reliever and fever reducer. Acetylsalicylic acid works by inhibiting the production of prostaglandins, which are hormone-like substances that contribute to inflammation and pain in the body. It is commonly found in over-the-counter medications such as aspirin and is also used for its anti-inflammatory and antiplatelet effects. Additionally, it may have potential applications in the treatment of certain types of cancers and neurodegenerative diseases.

InChI:InChI=1/C11H12O6/c1-6(12)17-10-8(15-2)4-7(11(13)14)5-9(10)16-3/h4-5H,1-3H3,(H,13,14)

Upstream product

• 530-57-4 3,5-dimethoxy-4-hydroxybenzoic acid 
• 75-36-5 acetyl chloride 
• 118-41-2 Eudesmic acid 
• 90985-68-5 3-(4-acetoxy-3,5-dimethoxyphenyl)prop-2-enoic acid 
• 108-24-7 acetic anhydride 
• 3068-32-4 1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 127-09-3 sodium acetate 
• 110-86-1 pyridine 
• 643-84-5 malvidin chloride 

Downstream Products

• 1166820-77-4 3-O-(4-acetoxy-3,5-dimethoxybenzoyl)catechin 
• 1315318-70-7 3,5-dimethoxy-4-(2-amino-3-prop-2-ynylsulfanylpropionyl)benzoic acid 4-guanidinobutyl ester 

Relevant articles and documents

Studies on the constituents of Anodendron affine Durce. II. Structure and synthesis of a new natural phenolic glucoside (Japanese)

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Novel Stachydrine-Leonurine Conjugate SL06 as a Potent Neuroprotective Agent for Cerebral Ischemic Stroke

As major active ingredients of the traditional Chinese medicine motherwort, stachydrine and leonurine were found to have protective effects against cerebral ischemia. However, their bioavailability in vivo was low, and their efficacy was unsatisfactory, which limited their further application. To solve these problems, the conjugates based on the structures of stachydrine and leonurine were designed and synthesized. SL06 was found to have neuronal cell survival improvement, neuronal apoptosis restraining, activation of superoxide dismutase (SOD) activity, and inhibition of lactic dehydrogenase (LDH), reactive oxygen species (ROS), malondialdehyde (MDA) in vitro. In vivo, the infarction size was significantly reduced by SL06 in the middle cerebral artery occlusion rat model. SL06 could also activate protein kinase B (AKT)/glycogen synthase kinase 3β (GSK-3β) activity and promoted the expression of antiapoptoticprotein Bcl-2. On the other hand, the expression of the apoptosis-associated protein cleaved caspase-3 would be inhibited as well. Thus, SL06 as the neuroprotective agent has potential for the treatment of cerebral ischemic stroke.

Menthyl syringate and preparation method and application thereof

The invention discloses menthyl syringate and a preparation method and application thereof. The preparation method of menthyl syringate comprises the steps that acetyl syringic acid and L-menthol areused as raw materials to conduct esterification so as to