39718-80-4

Basic information

• Product Name: [4-(benzylamino)phenyl]acetic acid
• Synonyms: benzeneacetic acid, 4-[(phenylmethyl)amino]-
• CAS NO: 39718-80-4
• Molecular Formula: C₁₅H₁₅NO₂
• Molecular Weight: 241.2851
• Mol File: 39718-80-4.mol

Chemical Properties

• Boiling Point: 432.2°C at 760 mmHg
• Flash Point: 215.2°C
• Density: 1.224g/cm³
• Vapor Pressure: 3.08E-08mmHg at 25°C
• Refractive Index: 1.645
• CAS DataBase Reference: [4-(benzylamino)phenyl]acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(benzylamino)phenyl]acetic acid(39718-80-4)
• EPA Substance Registry System: [4-(benzylamino)phenyl]acetic acid(39718-80-4)

Safety Data

• Hazardous Substances Data: 39718-80-4(Hazardous Substances Data)

Upstream product

• 14062-25-0 Ethyl 4-bromophenylacetate 
• 100-46-9 benzylamine 
• 57960-72-2 (4-benzylidenamino-phenyl)-acetic acid ethyl ester 
• 1197-55-3 4-aminophenylacetic acid 
• 100-52-7 benzaldehyde 
• 57960-76-6 ethyl 2-(4-(benzylamino)phenyl)acetate 
• 100-44-7 benzyl chloride 
• 5438-70-0 ethyl (4-amino-3,5-dibromophenyl)acetate 

Downstream Products

• 116665-37-3 2-[4-(acetyl-benzyl-amino)-phenyl]-3t-phenyl-acrylic acid 

Relevant articles and documents

Visible light-mediated oxidative decarboxylation of arylacetic acids into benzyl radicals: Addition to electron-deficient alkenes by using photoredox catalysts

Reactions of arylacetic acids bearing an amino group at the para-position in the benzene ring with alkenes in the presence of a catalytic amount of transition metal polypyridyl complexes as photocatalysts under visible light illumination proceed smoothly to give the corresponding benzylated products via oxidative decarboxylation in good to high yields.

Efficient one-pot synthesis of biologically active polysubstituted aromatic amines

An efficient and modular one-pot synthesis of polysubstituted aromatic amines by a mild reductive amination procedure is described and the biological potential of these nitrogen-centered compounds is demonstrated by growth inhibition of murine connective tissue cells and microscopy-based morphological studies.

Thiourea-catalyzed direct reductive amination of aldehydes

A hydrogen-bond-catalyzed direct reductive amination of aldehydes is reported. The acid- and metal-free process uses thiourea as organocatalyst and the Hantzsch ester for transfer-hydrogenation and allows for the high-yielding synthesis of diverse amines. Georg Thieme Verlag Stuttgart.

Hypolipidaemic compounds and compositions

Certain substituted aralkylanilines in which the aromatic aniline ring carries, at the para position to the amino function, a substituent which comprises a carboxylic acid, salt or ester, an alkyl, hydroxyalkyl, cyano or acyl group, have hypolipidaemic ac

Phenylacetic acid derivatives

The present invention relates to phenylacetic acid derivatives having the general formula: SPC1 In which R1 represents a lower alkyl radical, a lower alkenyl radical, a lower alkynyl radical or an aryl(lower) alkyl radical, R2 represents hydrogen or a methyl radical, their esters and their salts with bases and acids. Said derivatives have in particular an analgesic and/or anti-inflammatory activity.