3974-99-0Relevant articles and documents
Findings supporting the natural formation of trichloroacetic acid in soil
Hoekstra, Eddo J.,De Leer, Ed W. B.,Brinkman, Udo A. Th
, p. 2875 - 2883 (1999)
The concentrations of trichloroacetic acid (TCAA) in soil and of chlorinated solvents in soil air from simultaneously taken samples from four sites are presented. The data show that there is a significant positive correlation between the concentrations of TCAA and chloroform - but not between TCAA and other chlorinated solvents - in soil. The calculated half-life of TCAA shows that the contribution of decarboxylation to the chloroform concentration in soil is negligible. Since TCCA and chloroform were found to be formed from humic acids in the chloroperoxidase (CPO)-mediated reaction and CPO activity has been detected in soil, the observed correlation between the concentrations of TCAA and chloroform provides novel support for the hypothesis that TCAA is formed naturally in soil.
Neutral Trichloroacetylations of Alcohols by Hexachloroacetone
Freedlander, Richard S.,Bryson, Thomas A.,Dunlap, R. Bruce,Schulman, E. M.,Lewis, Charles A.
, p. 3519 - 3521 (2007/10/02)
The addition of simple alcohols in hexachloroacetone (HCA) in the presence of strong hydrogen bond acceptors (e.g., dimethylformamide) results in a high yield of the corresponding trichloroacetate (via a haloform reaction scheme).The trichloroacetylation reactions are carried out under neutral conditions, and the resultant ester can easily be separated from the reaction mixture via extraction/distillation procedures.Kinetic evidence demonstrates that the trichloroacetylation of alcohols by HCA is a stereoselective process, and further studies suggest that the catalytic role of the acceptors is of a hydrogen bonding nature.