39884-48-5

Basic information

• Product Name: 4-AMINO-2-BUTANOL
• Synonyms: RARECHEM AL BW 1326;4-amino-2-butano;4-AMINO-2-BUTANOL;4-aminobutan-2-ol;4-Aminobutane-2-ol;4-Amino-2-butanol,99+%;4-Amino-2-butanol,98%;4-AMino-2-butanol, 98% 1GR
• CAS NO: 39884-48-5
• Molecular Formula: C₄H₁₁NO
• Molecular Weight: 89.14
• EINECS: 254-673-2
• Product Categories: Amino Alcohols;Organic Building Blocks;Oxygen Compounds
• Mol File: 39884-48-5.mol
• Article Data: 10

Chemical Properties

• Melting Point: 8.72°C (estimate)
• Boiling Point: 103-104 °C (34 mmHg)
• Flash Point: 55.6 °C
• Appearance: Clear colorless to faintly yellow/Liquid
• Density: 0.93
• Vapor Pressure: 0.531mmHg at 25°C
• Refractive Index: 1.4518-1.4538
• PKA: 15.01±0.20(Predicted)
• CAS DataBase Reference: 4-AMINO-2-BUTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-2-BUTANOL(39884-48-5)
• EPA Substance Registry System: 4-AMINO-2-BUTANOL(39884-48-5)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 45-36/37/39-25-26
• RIDADR: UN2735 8/PG 3
• Hazardous Substances Data: 39884-48-5(Hazardous Substances Data)

Usage

Chemical Properties

Clear colorless to faintly yellow liquid

InChI:InChI=1/C4H11NO/c1-4(6)2-3-5/h4,6H,2-3,5H2,1H3/p+1/t4-/m1/s1

Upstream product

• 4368-06-3 3-hydroxybutanenitrile 
• 89333-64-2 2-((E)-But-2-enyl)-1,1,1,3,3,3-hexamethyl-disilazane 
• 107-89-1 acetaldol 
• 82521-17-3 3-hydroxy-butyraldehyde-oxime 
• 7732-18-5 water 
• 38802-24-3 4-hydroxyvaleric amide 
• 7726-95-6 bromine 
• 7647-01-0 hydrogenchloride 
• 144095-97-6 N,N'-bis-(3-hydroxy-butyl)-urea 
• 109-73-9 N-butylamine 
• 1039627-16-1 CH₂CHCH₂CH₂NH₂BH₃ 
• 42563-40-6 4-isocyano-butan-2-ol 
• 42562-45-8 6-methyl-5,6-dihydro-4H-[1,3]oxazine 

Downstream Products

• 143-26-0 4-tetradecylamino-butan-2-ol 
• 24621-61-2 1,3-butanediol 
• 373384-25-9 2-(3-hydroxy-butylamino)-6-phenyl-4-trifluoromethyl-nicotinonitrile 
• 1009557-19-0 4-[[(4-methoxymethoxy)phenyl]amino]butan-1-ol 
• 1085758-13-9 C₂₃H₂₁F₃N₆O₃ 
• 1190398-46-9 N-(3-hydroxybutyl)-4-methylbenzene-1-sulfonamide 
• 1243256-33-8 1-(N-3-butanol)-4-(N-maleimidomethyl)cyclohexane carboxamide 
• 54614-95-8 (3-Oxo-butyl)-carbamic acid tert-butyl ester 
• 19278-47-8 N-(2-hydroxybutyl)benzamide 
• 6638-38-6 N-(3-hydroxybutyl)benzamide 
• 23645-04-7 4-Aminobutan-2-one 

Relevant articles and documents

Remote C(sp3)-H Oxygenation of Protonated Aliphatic Amines with Potassium Persulfate

This letter describes the development of a method for selective remote C(sp3)-H oxygenation of protonated aliphatic amines using aqueous potassium persulfate. Protonation serves to deactivate the proximal C(sp3)-H bonds of the amine substrates and also renders the amines soluble in the aqueous medium. These reactions proceed under relatively mild conditions (within 2 h at 80 °C with amine as limiting reagent) and do not require a transition metal catalyst. This method is applicable to a variety of types of C(sp3)-H bonds, including 3°, 2°, and benzylic C-H sites in primary, secondary, and tertiary amine substrates.

Selective functionalization of amino acids in water: A synthetic method via catalytic C-H bond activation [17]

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PROTECTION OF PRIMARY AND SECONDARY AMINES IN THE HYDROBORATION REACTION

Trimethylsilyl groups are efficient to protect the N-H bonds of olefinic amines in the hydroboration reaction with BMS; deprotection is easily run with methanol and affords aminoorganoboranes which can be used without any oxydation.