39927-08-7

Basic information

• Product Name: POLY(ETHYLENE GLYCOL) BIS(CARBOXYMETHYL) ETHER
• Synonyms: POLYETHYLENE GLYCOL 600 DIACID;POLY(ETHYLENE GLYCOL) BIS(CARBOXYMETHYL) ETHER;POLYGLYCOL 600 DIACID;POLYGLYCOL DIACID;polyoxyethylene bis(acetic acid);POLY(ETHYLENE GLYCOL) BIS(CARBOXYMETHYL) ETHER, AVERAGE MN CA. 600;POLY(ETHYLENE GLYCOL) BIS(CARBOXYMETHYL) ETHER, AVERAGE MN CA. 250;α,ω-bis(2-carboxymethyl)polyethylene glycol
• CAS NO: 39927-08-7
• Molecular Formula: C4H10O5
• Molecular Weight: 138.1192
• Product Categories: Polydispersed PEG;PEG
• Mol File: 39927-08-7.mol
• Article Data: 27

Chemical Properties

• Boiling Point: 427.7°C at 760 mmHg
• Flash Point: >230 °F
• Appearance: /
• Density: 1.302 g/mL at 25 °C
• Vapor Pressure: 4.14E-09mmHg at 25°C
• Refractive Index: n20/D 1.470
• Storage Temp.: 2-8°C
• CAS DataBase Reference: POLY(ETHYLENE GLYCOL) BIS(CARBOXYMETHYL) ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: POLY(ETHYLENE GLYCOL) BIS(CARBOXYMETHYL) ETHER(39927-08-7)
• EPA Substance Registry System: POLY(ETHYLENE GLYCOL) BIS(CARBOXYMETHYL) ETHER(39927-08-7)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45-27
• RIDADR: UN 1760 8/PG 2
• WGK Germany: 1
• Hazardous Substances Data: 39927-08-7(Hazardous Substances Data)

Usage

Uses

Poly(ethylene glycol) bis(carboxymethyl) ether may used as a plasticizer.

General Description

Poly(ethylene glycol) bis(carboxymethyl) ether has bifunctional carboxylic acid end groups.

InChI:InChI=1/C2H4O3.C2H6O2/c3-1-2(4)5;3-1-2-4/h3H,1H2,(H,4,5);3-4H,1-2H2

Upstream product

• 79-11-8 chloroacetic acid 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 
• 107-21-1 ethylene glycol 
• 79-08-3 bromoacetic acid 
• 111-46-6 diethylene glycol 
• 4792-15-8 Pentaethylene glycol 
• 211746-79-1 di-tert-butyl 3,6,9,12,15,18-hexaoxaicosane-1,20-dioate 
• 112-60-7 Tetraethylene glycol 
• 211746-77-9 di-tert-butyl 2,2’-(2,2’-oxybis(ethane-1,2-diyl)bis(oxy))diacetate 
• 2615-15-8 pentaethylene glycol 
• 211746-80-4 3,6,9,12,15,18,21-heptaoxatricosane-1,23-dioic acid di-tert-butyl ester 
• 211746-78-0 di-tert-butyl 3,6,9,12,15-pentaoxaheptadecanedioate 
• 132684-09-4 di-tert-butyl 3,6,9,12-tetraoxatetradecanedioate 

Downstream Products

• 146773-32-2 2-[2-[2-(2-benzyloxy-2-oxo-ethoxy)ethoxy]ethoxy]acetic acid 
• 67615-89-8 N,N,N',N'-Tetraoctyl-3,6-dioxa-octandisaeure-diamid 
• 1612221-37-0 C₃₈H₅₆N₂O₉ 
• 1609647-62-2 [2-(4-aminophenoxycarbonylmethoxy)ethoxy]acetic acid 4-aminophenyl ester 
• 1609647-63-3 [2-(4-isocyanatophenoxycarbonylmethoxy)ethoxy]acetic acid 4-isocyanatophenyl ester 
• 1232884-88-6 ST₅₅₈₇ 
• 883564-93-0 13,13-dimethyl-11-oxo-3,6,9,12-tetraoxatetradecan-1-oic acid 
• 72469-41-1 2-(2-Dipropylcarbamoylmethoxy-ethoxy)-N,N-dioctadecyl-acetamide 
• 41775-36-4 1,4,7,13-tetraoxa-10,16-diazacyclooctadecane 
• 145058-24-8 N,N-Dibenzyl-2-[2-(2-{2-[(dibenzylcarbamoyl)-methoxy]-ethoxy}-ethoxy)-ethoxy]-acetamide 

Relevant articles and documents

Effective Na+-Binding Ability and Molecular Assembly of an Alkylamide-Substituted Penta(ethylene)glycol Derivative

A new amphiphilic penta(ethylene glycol) derivative (1) bearing two hydrogen-bonding -CONHC14H29 chains was prepared. Compound 1 exhibited ion-recognition abilities for Na+ and K+, and its properties were compared with those of the macrocyclic [18]crown-6. Although both compound 1 and [18]crown-6 have six ether oxygen atoms (-OC2H2-), the Na+-binding ability of the former was much higher than that of the latter. K+-binding ability of cyclic [18]crown-6 was much higher than its Na+-binding ability, while the reverse was true for acyclic compound 1. Single-crystal X-ray structural analysis of Na+·1·B(Ph)4-·(hexane)2 at 100 K revealed the existence of a wrapped Na+-coordination by six ether and one carbonyl oxygen atoms of 1, which was further stabilized by intramolecular N-H···O= hydrogen-bonding interactions. The complex phase transition during glass (G) formation and recrystallization was confirmed in the thermal cycle of Na+·1·B(Ph)4-, whose molten state showed two kinds of liquid phases, Na+-complexed (Na+·1) + B(Ph)4- and completely dissociated Na+ + 1 + B(Ph)4-. The Na+ conductivity of the molten state was 2 orders of magnitude higher than that of the G phase.

BENZODICYCLOALKANE DERIVATIVE, PREPARATION METHOD AND USE THEREOF

It is provided herein a benzobicycloalkane derivative, and a preparation method and use thereof. In particular, it is provided herein a compound of Formula (I), or a pharmaceutically acceptable salt, stereoisomer or solvate thereof, a preparation method, and a use thereof in preparation of drugs for treating pain.

SMALL MOLECULES

Compounds having the general structure A - L - B are presented wherein A and B are independently an E3 ubiquitin ligase protein binding ligand compound of formula 1A or 1 B. Pharmaceutical compositions comprising these compounds and methods of use are also presented.