40133-22-0

Basic information

• Product Name: 2-(4-BROMOPHENYL)THIOPHENE
• Synonyms: 2-(4-BROMOPHENYL)THIOPHENE;2-(4-Bromophenyl)thiophene 97%;1-Bromo-4-(thien-2-yl)benzene;2-(4-Bromophenyl)thiophene97%
• CAS NO: 40133-22-0
• Molecular Formula: C₁₀H₇BrS
• Molecular Weight: 239.13
• Product Categories: Halogenated Heterocycles;Heterocyclic Building Blocks;Thiophenes;ThiophenesBuilding Blocks
• Mol File: 40133-22-0.mol
• Article Data: 37

Chemical Properties

• Melting Point: 95-99 °C(lit.)
• Boiling Point: 307 °C at 760 mmHg
• Flash Point: 139.5 °C
• Appearance: /
• Density: 1.49 g/cm³
• Vapor Pressure: 0.00135mmHg at 25°C
• Refractive Index: 1.628
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 2-(4-BROMOPHENYL)THIOPHENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-BROMOPHENYL)THIOPHENE(40133-22-0)
• EPA Substance Registry System: 2-(4-BROMOPHENYL)THIOPHENE(40133-22-0)

Safety Data

• RIDADR: UN 3335
• WGK Germany: 3
• Hazardous Substances Data: 40133-22-0(Hazardous Substances Data)

Usage

General Description

2-(4-Bromophenyl)thiophene is a chemical compound with the molecular formula C10H7BrS. It is a member of the thiophene family, which is a five-membered aromatic ring with one sulfur atom. The presence of the bromine atom in the 4-position of the phenyl group makes this compound useful as a building block for the synthesis of various organic compounds, including pharmaceuticals and materials. It has been studied for its potential applications in organic electronics and optoelectronic devices due to its unique electronic properties. Additionally, 2-(4-Bromophenyl)thiophene may also have potential in medicinal chemistry as a scaffold for drug design due to its ability to interact with biological systems. Overall, this compound has a range of potential applications in various fields due to its unique chemical structure and properties.

InChI:InChI=1/C10H7BrS/c11-9-5-3-8(4-6-9)10-2-1-7-12-10/h1-7H

Upstream product

• 3437-95-4 2-Iodothiophene 
• 5467-74-3 4-Bromophenylboronic acid 
• 59099-79-5 4-(4-bromophenyl)-3-butyn-1-ol 
• 1003-09-4 2-bromothiophene 
• 6165-68-0 thiophene boronic acid 
• 106-37-6 1.4-dibromobenzene 
• 589-87-7 1,4-bromoiodobenzene 
• 5713-61-1 thiophen-2-yl magnesium bromide 
• 193978-23-3 2-thiopheneboronic acid pinacol ester 
• 188290-36-0 thiophene 
• 106-40-1 4-bromo-aniline 
• 1509927-77-8 4-[3-(4-bromophenyl)-3-oxopropyl][1,3]dithietan-2-one 
• 1509927-68-7 S-[4-(4-bromophenyl)-1-(1-ethylsulfinyl)-4-oxobutyl]-O-isopropyl carbonodithioate 
• 1861-48-9 dithiocarbonic acid S-[2-(4-bromo-phenyl)-2-oxo-ethyl] ester O-ethyl ester 

Downstream Products

• 83495-24-3 5,5'-Bis-(4-bromo-phenyl)-[2,3']bithiophenyl 
• 649569-57-3 methyl 5-(4-bromophenyl)thiophene-2-carboxylate 
• 62404-41-5 [5-(4-bromo-phenyl)-thiophen-2-yl]-acetonitrile 
• 62403-67-2 [5-(4-bromo-phenyl)-thiophen-2-yl]-acetic acid 
• 1056474-34-0 4,4,5,5-tetramethyl-2-(4-(thiophen-2-yl)phenyl)-1,3,2-dioxaborolane 
• 1257985-11-7 ((5-(4-bromophenyl)thiophen-2-yl)ethynyl)triisopropylsilane 
• 35294-37-2 1-(4-(thiophen-2-yl)phenyl)ethanone 
• 183619-15-0 2-bromo-5-(4-bromophenyl)thiophene 

Relevant articles and documents

Synthesis of Substituted Thiophenes through Dehydration and Heterocyclization of Alkynols

A protocol was described for obtaining a variety of substituted thiophenes with functional potential via metal-free dehydration and sulfur cyclization of alkynols with elemental sulfur (S8) or EtOCS2K in moderate-to-good yields. The method provides the base-free generation of a trisulfur radical anion (S3?-) and its addition to alkynes as an initiator. This research broadens the applications of S3?-in the synthesis of sulfur-containing heterocycles.

Fabrication of Graphitic Carbon Nitride-Based Film: An Emerged Highly Efficient Catalyst for Direct C—H Arylation under Solar Light

Photoredox C—H bond formation can proceed in aerobic environment under solar light and has therefore become attractive. Nowadays, different types of expensive novel metal complexes and nanomaterials have been urbanized as photocatalysts for direct C—H bon

Access to Substituted Thiophenes through Xanthate-Mediated Vinyl C(sp2)-Br Bond Cleavage and Heterocyclization of Bromoenynes

An environmentally sustainable strategy for the chemoselective heterocyclization of bromoenynes through a transition-metal-free sulfuration/cyclization process is reported. Using inexpensive and safe EtOCS2K as a thiol surrogate and tetrabutylphosphonium bromide and H2O as a mixed solvent, the reaction provided a range of substituted thiophenes in moderate to good yields. In addition, 2,3,4,5-tetrasubstituted thiophenes were able to be prepared under mild reaction conditions by electrophilic heterocyclization with NH4I and EtOCS2K in good yields.