40197-15-7

Upstream product

• 4190-14-1 N-(2-oxo-2-phenylethyl)benzamide 
• 101091-17-2 N-(β-hydrazono-phenethyl)-benzamide 
• 100-52-7 benzaldehyde 
• 1666-17-7 benzaldehyde p-toluenesulfonylhydrazone 
• 24395-14-0 N-(p-tolylsulfonyl)-2-phenylaziridine 
• 100-42-5 styrene 
• 5504-50-7 Benzaldehyde benzyloxycarbonylhydrazone 
• 135942-02-8 N^α-benzyl-N^α-Z hydrazine 

Downstream Products

• 33063-35-3 3,6-diphenyl-[1,2,4]triazine 

Relevant academic research and scientific papers

Oxidative Dehydrogenative [3+3] Annulation of Benzylhydrazines with Aziridines Leading to Tetrahydrotriazines

Oxidative dehydrogenative [3+3] annulation of benzylhydrazines with N-sulfonylaziridines is described. A series of complex tetrahydro-1,2,4-triazines were produced under mild reaction conditions.

One-Pot Acid-Catalyzed Ring-Opening/Cyclization/Oxidation of Aziridines with N-Tosylhydrazones: Access to 1,2,4-Triazines

A new, three-step, telescoped reaction sequence for the regioselective conversion of N-tosyl hydrazones and aziridines to 3,6-disubstituted and 3,5,6-trisubstituted 1,2,4-triazines is described. The process involves an efficient nucleophilic ring opening of the aziridine, giving access to a wide range of aminohydrazones, isolated with excellent yields. A “one-pot” procedure, combining the ring opening with a cyclization and an oxidation step, allows the preparation of diversified triazines in good yields.