Welcome to LookChem.com Sign In|Join Free
  • or
Propan-2-yl (4-bromophenyl)carbamate, also known as bromperidol, is a butyrophenone class chemical compound primarily used as an antipsychotic medication. It functions by blocking the effects of dopamine in the brain, which helps to alleviate symptoms of schizophrenia and other psychotic disorders. Bromperidol is often prescribed when other antipsychotic medications have been ineffective and is available in both oral and injectable forms.

40427-42-7

Post Buying Request

40427-42-7 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

40427-42-7 Usage

Uses

Used in Pharmaceutical Industry:
Propan-2-yl (4-bromophenyl)carbamate is used as an antipsychotic medication for the treatment of schizophrenia and other psychotic disorders. It is prescribed when other antipsychotic medications have been ineffective, providing an alternative treatment option for managing symptoms.
Used in Healthcare:
Propan-2-yl (4-bromophenyl)carbamate is used as a therapeutic agent to alleviate symptoms of schizophrenia and other psychotic disorders by blocking the effects of dopamine in the brain. It is administered under the supervision of a healthcare professional to ensure safe and effective treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 40427-42-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,4,2 and 7 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 40427-42:
(7*4)+(6*0)+(5*4)+(4*2)+(3*7)+(2*4)+(1*2)=87
87 % 10 = 7
So 40427-42-7 is a valid CAS Registry Number.

40427-42-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name propan-2-yl N-(4-bromophenyl)carbamate

1.2 Other means of identification

Product number -
Other names Carbamic acid,4-bromophenyl,1-methylethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:40427-42-7 SDS

40427-42-7Relevant academic research and scientific papers

(PPh4)2: A Copper Hydride Nanocluster with a Bisquare Antiprismatic Core

Baek, Woonhyuk,Bootharaju, Megalamane S.,Deng, Guocheng,H?kkinen, Hannu,Hyeon, Taeghwan,Lee, Sanghwa,Malola, Sami,Zheng, Nanfeng

, p. 13974 - 13981 (2020/09/18)

Atomically precise coinage metal (Au, Ag, and Cu) nanoclusters (NCs) have been the subject of immense interest for their intriguing structural, photophysical, and catalytic properties. However, the synthesis of Cu NCs is highly challenging because of low reduction potential and high reactivity of copper, demonstrating the need for new synthetic methods using appropriate ligand combinations. By designing a diamine-assisted synthetic strategy, here we report the synthesis and total structure characterization of a box-like dianionic Cu NC [Cu32(PET)24H8Cl2](PPh4)2 coprotected by 2-phenylethanethiolate (PET), hydride, and chloride ligands. Its crystal structure comprises a rare bisquare antiprismatic Cu14H8 core, assembled by two square antiprisms by edge sharing, followed by hydride binding. The rod-shaped Cu14H8 core is clamped by two complex Cu7(PET)11Cl and two simple Cu2PET metal ligand frameworks, constructing the complete structure of Cu32 NC. The presence, number, and location of hydrides are established by combined experimental and density functional theory results. The electronic structure calculations show the cluster as a zero-free-electron system, reproduce well the measured optical absorption spectrum, and explain the main absorption features. Furthermore, the Cu32 cluster is found to be a highly active homogeneous catalyst for C-N bond formation in aniline carbonylation reactions at room temperature. We hope that new findings in this work will stimulate and expand the research on Cu and other active metal NCs.

Copper-catalyzed carbonylation of anilines by diisopropyl azodicarboxylate for the synthesis of carbamates

Usman, Muhammad,Ren, Zhi-Hui,Wang, Yao-Yu,Guan, Zheng-Hui

, p. 107542 - 107546 (2016/11/29)

A Cu-catalyzed efficient methodology for the direct carbonylation of anilines has been developed. The N-H bond cleavage and N-C bond formation were notably achieved under solvent-free conditions and a variety of carbamates were synthesized from readily available anilines using diisopropyl azodicarboxylate (DIAD) as the carbonylating source.

An efficient one-pot synthesis of: N, N ′-disubstituted ureas and carbamates from N -acylbenzotriazoles

Singh, Anoop S.,Kumar, Dhananjay,Mishra, Nidhi,Tiwari, Vinod K.

, p. 84512 - 84522 (2016/10/12)

A facile and high-yielding one-pot synthesis of carbamates and N,N′-disubstituted symmetrical ureas from N-acylbenzotriazoles has been devised. It is believed that, the intermediate acyl-azide undergo Curtius rearrangement and in different solvents gives different products i.e. carbamates in alcohols and N,N′-disubstituted symmetrical urea in THF.

Metal free oxidative coupling of aryl formamides with alcohols for the synthesis of carbamates

Reddy, N. Veera,Prasad, K. Rajendra,Reddy, P. Sudhir,Lakshmi Kantam,Reddy, K. Rajender

supporting information, p. 2172 - 2175 (2014/04/03)

A direct transformation of N-aryl formamides to the corresponding carbamates via the formation of isocyanate intermediates is achieved in good yields using hypervalent iodine as an oxidant. This journal is

Homolytic Annulation by Reaction of Imidoyl Radicals with Diethyl Azodicarboxylate: a New Route to Nitrogen Heterocycle Derivatives

Leardini, Rino,Nanni, Daniele,Tundo, Antonio,Zanardi, Giuseppe

, p. 757 - 758 (2007/10/02)

An easily effected aromatic annulation is described, involving the reaction of arylimidoyl radicals with diethyl azodicarboxylate to give 1,2-dihydro-1,2-diethoxycarbonyl-benzo- and -pyrido-1,2,4-triazines.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 40427-42-7