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40431-64-9 Usage

Uses

Treatment of attention deficit/hyperactivity disorder.

Definition

ChEBI: A methyl phenyl(piperidin-2-yl)acetate in which both stereocentres have R configuration. It is the active enantiomer in the racemic drug methylphenidate.

Check Digit Verification of cas no

The CAS Registry Mumber 40431-64-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,4,3 and 1 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 40431-64:
(7*4)+(6*0)+(5*4)+(4*3)+(3*1)+(2*6)+(1*4)=79
79 % 10 = 9
So 40431-64-9 is a valid CAS Registry Number.

40431-64-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	dexmethylphenidate

1.2 Other means of identification

Product number	-
Other names	Dexmedetomidine (USAN/INN)

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:40431-64-9 SDS

40431-64-9Upstream product

40431-64-9Downstream Products

40431-64-9Relevant articles and documents

An efficient large scale resolution of (±)-threo-methylphenidate hydrochloride (Ritalin hydrochloride)

Prashad, Mahavir,Har, Denis,Repic, Oljan,Blacklock, Thomas J.,Giannousis, Peter

, p. 3111 - 3116 (1999)

An efficient and large scale preparation of (2R,2'R)-(+)-threo-methylphenidate hydrochloride (3) by the resolution of (±)-threo-methylphenidate hydrochloride (1) salt with O,O'-dibenzoyl-D-(+)-tartaric acid in the presence of 4-methylmorpholine is described.

α-C-H Bond Functionalization of Unprotected Alicyclic Amines: Lewis-Acid-Promoted Addition of Enolates to Transient Imines

Kim, Jae Hyun,Paul, Anirudra,Ghiviriga, Ion,Seidel, Daniel

, p. 797 - 801 (2021/02/06)

Enolizable cyclic imines, obtained in situ from their corresponding lithium amides by oxidation with simple ketone oxidants, are readily alkylated with a range of enolates to provide mono- and polycyclic β-aminoketones in a single operation, including the natural product (±)-myrtine. Nitrile anions also serve as competent nucleophiles in these transformations, which are promoted by BF3 etherate. β-Aminoesters derived from ester enolates can be converted to the corresponding β-lactams.

An Improved and Efficient Process for the Production of Highly Pure Dexmethylphenidate Hydrochloride

Xing, Long-Xuan,Shen, Cheng-Wu,Sun, Yuan-Yuan,Huang, Lei,Zheng, Yong-Yong,Li, Jian-Qi

, p. 1298 - 1303 (2017/03/27)

The present work describes an efficient and commercially viable process for the synthesis of dexmethylphenidate hydrochloride (1), a mild nervous system stimulant. The overall yield is 23% with ~99.9% purity (including seven chemical steps). Formation and control of possible impurities are also described in this report.

CAS

40431-64-9