189074-35-9

Upstream product

• 404574-12-5 methyl 2,3,5-tri-O-benzoyl-1-α-L-arabinofuranoside 
• 108-24-7 acetic anhydride 
• 3795-68-4 methyl α-L-arabinofuranoside 
• 6778-37-6 L-(-)-arabinose 1’ methyl ether 
• 98-88-4 benzoyl chloride 
• 64-19-7 acetic acid 
• 10323-20-3 D-Arabinose 
• 87-72-9 L-(+)-arabinose 
• 13039-64-0 (2S,3R,4R)-2-(hydroxymethyl)-5-methoxytetrahydrofuran-3,4-diol 
• 5328-37-0 L-arabinose 
• 42793-97-5 2,3,5-tri-O-benzoyl-1-O-methyl-α-L-arabinofuranose 

Downstream Products

• 100645-43-0 p-nitrophenyl 2,3,5-tri-O-benzoyl-α-L-arabinofuranoside 
• 22796-65-2 p-nitrophenyl α-L-arabinofuranoside 
• 134149-34-1 allyl-α-L-arabinofuranoside 
• 1027638-23-8 2-chloro-4-nitrophenyl 2,3,5-tri-O-benzoyl-α-L-arabinofuranoside 
• 189074-42-8 3-(2,3,5-tri-O-benzoyl-β-D-arabinofuranosyl)uracil 
• 1311109-69-9 2,3,5-tri-O-benzoyl-α-L-arabinofuranosyl ortho-hexynylbenzoate 
• 1311109-70-2 2,3,5-tri-O-benzoyl-β-L-arabinofuranosyl ortho-hexynylbenzoate 
• 42868-96-2 2,3,5-tri-O-benzoyl-α-L-arabinofuranosyl bromide 
• 20290-92-0 1-<2',3',5'-Tri-O-benzoyl-α-L-arabinofuranosyl>thymine 
• 1146632-13-4 C₂₉H₂₃N₃O₉ 
• 16033-24-2 1-<α-L-Arabinofuranosyl>thymine 
• 137147-01-4 3'-O-Methylsulfonyl-5'-O-triphenylmethyl-α-L-thymidine 
• 7791-71-1 1-(5-O-trityl-2-deoxy-β-D-lyxofuranosyl)thymine 

Relevant academic research and scientific papers

MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF

The present disclosure provides oligomeric compounds comprising a modified oligonucleotide having at least one stereo-non-standard nucleoside. An oligomeric compound comprising a modified oligonucleotide consisting of 12-30 linked nucleosides, wherein at least one nucleoside of the modified oligonucleotide is a stereo-non-standard nucleoside; and wherein the oligomeric compound is selected from among an RNAi compound, a modified CRISPR compound, and an artificial mRNA compound.

MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF

The present disclosure provides oligomeric compounds comprising a modified oligonucleotide having at least one stereo-non-standard nucleoside.

Enzymatic synthesis of alkyl arabinofuranosides using a thermostable α-L-arabinofuranosidase

A thermostable α-L-arabinofuranosidase was tested for its ability to perform transglycosylation with different alcohol acceptors. Reactions were characterized by high rates with optimal synthesis being obtained within 10 min. Both primary and secondary al

Synthesis of 1-(3'-azido-2',3'-dideoxy-α-L-threo-pentofuranosyl)thymine as a potential anti-HIV agent

Starting from methyl 2,3,5-tri-O-benzoyl-α-L-arabinofuranoside, a multistep synthesis of the C-4' epimer of AZT is described. Glycosylation of silylated thymine with 2,3,5-tri-O-benzoyl-L-arabinofuranosyl acetate (5) affords the α-nucleoside 7 after debenzoylation. Deoxygenation at C-2' of the selectively protected 8, followed by displacement of a 3'-methanesulfonyl group by lithium azide leads to the title compound which did not exhibit antiviral activity against HIV-1.