40646-17-1

Usage

Uses

Used in Fragrance Industry:
8-hydroxyoctyl acetate is used as a fragrance ingredient for its ability to add a sweet, fruity note to perfumes and personal care products.
Used in Cosmetic Industry:
8-hydroxyoctyl acetate is used as a solvent and a flavoring agent in cosmetics, contributing to the pleasant scent and texture of lotions, creams, hair care products, and other personal care items.
Used in Food and Beverage Industry:
8-hydroxyoctyl acetate is used in the production of flavors and fragrances for food and beverages, enhancing the sensory experience of various consumable products.
All these applications are made possible due to its safety for use in cosmetics and its wide compatibility with different product formulations.

Upstream product

• 629-41-4 1,8-Octanediol 
• 108-24-7 acetic anhydride 
• 153164-82-0 1-(allyloxy)-8-(prop-2-yn-1-yloxy)octane 
• 1403675-04-6 8-(alyloxy)octyl acetate 
• 153164-83-1 8-allyloxyoctan-1-ol 
• 5048-35-1 oct-7-en-1-yl acetate 
• 64-19-7 acetic acid 
• 108-05-4 vinyl acetate 
• 141-78-6 ethyl acetate 
• 75-36-5 acetyl chloride 
• 3992-48-1 1,8-octanediyl diacetate 

Downstream Products

• 14113-05-4 (E)-10-hydroxy-dec-2-enoic acid 
• 60609-53-2 (Z)-14-Methyl-8-Hexadecenal 
• 35153-20-9 (E)-12-tetradecene-1-ol acetate 
• 35153-20-9 (Z)-Δ¹²-tetradecenyl acetate 
• 71777-34-9 (R)-(-)-10-methyl-1-dodecanol acetate 
• 116206-55-4 8-tosyloxyoctyl acetate 
• 929-48-6 7-formylheptanoic acid 

Relevant academic research and scientific papers

Selective Monoacetylation of Symmetrical Diols and Selective Monodeacetylation of Symmetrical Diacetates Using HY-Zeolite as Reusable Heterogeneous Catalyst

HY-Zeolite has been found to be an efficient and reusable catalyst for selective monoacetylation of symmetrical diols and selective monodeacetylation of symmetrical diacetates to form the products in high yields.

Noncross-linked polystyrene nanoencapsulation of ferric chloride: A novel and reusable heterogeneous macromolecular Lewis acid catalyst toward selective acetylation of alcohols, phenols, amines, and thiols

Ferric chloride has been successfully nanoencapsulated for the first time on a non-cross-linked polystyrene matrix as the shell material via the coacervation technique. The resulting polystyrene nanoencapsulated ferric chloride was used as a novel and rec

An Intramolecular Iodine-Catalyzed C(sp3)?H Oxidation as a Versatile Tool for the Synthesis of Tetrahydrofurans

The formation of ubiquitous occurring tetrahydrofuran patterns has been extensively investigated in the 1960s as it was one of the first examples of a non-directed remote C?H activation. These approaches suffer from the use of toxic transition metals in overstoichiometric amounts. An attractive metal-free solution for transforming carbon-hydrogen bonds into carbon-oxygen bonds lies in applying economically and ecologically favorable iodine reagents. The presented method involves an intertwined catalytic cycle of a radical chain reaction and an iodine(I/III) redox couple by selectively activating a remote C(sp3)?H bond under visible-light irradiation. The reaction proceeds under mild reaction conditions, is operationally simple and tolerates many functional groups giving fast and easy access to different substituted tetrahydrofurans.

Method of manufacturing [...]

PROBLEM TO BE SOLVED: To provide a method of practically producing (Z)-14-methylhexadec-8-enal in total 5 processes using inexpensive octane-1,8-diol as a starting raw material and without using pyridinium chlorochromate or hexamethylphosphoric triamide.SOLUTION: A method of producing (Z)-14-methylhexadec-8-enal includes total 5 processed including a first process of monoacetylation of octane-1,8-diol as a starting raw material, a second process of oxidation, a third process of reacting phosphonium salt having a 6-methyloctyl group with ylide generated from a base, a fourth process of carrying out alcoholysis, and a fifth process of oxidation.

A new approach to the synthesis of royal jelly acid

A new approach to the synthesis of royal jelly acid (trans-10-hydroxy-2- decenoic acid) was proposed starting from 1,8-octanediol, which included selective monoprotection of 1,8-octanediol with acetic anhydride, oxidation, Wittig-Horner reaction, and hydrolysis and acidification, four steps in total, to yield the product. Overall yield is 80.2%.

A facile synthesis of the sex pheromone of Grapholitha molesta

The sex pheromone of Grapholitha molesta, (Z/E)-8-dodecylen-1-ol acetate, was easily synthesized in an overall yield of 41.5% with 1,8-octanediol as starting material via mono-esterification, PCC oxidation, and Witting reactions. The Z/E ratio is 83:17. Configuration transformation of Z/E 83:17 compound with sodium nitrite and nitric acid resulted in the production of a compound with Z/E 24:76. The products were confirmed by IR, 1H NMR, and MS spectral data.

Elaboration of the ether cleaving ability and selectivity of the classical Pearlman's catalyst [Pd(OH)2/C]: Concise synthesis of a precursor for a myo-inositol pyrophosphate

The cleavage of propargyl, allyl, benzyl, and PMB ethers by Pd(OH) 2/C can be tuned in that order, by varying the reaction conditions. Other moieties such as C-C double bonds, esters, trityl ether, p-bromo and p-nitrobenzyl ethers are stable to these reaction conditions. Cleavage of allyl ethers can be made catalytic by using 1:1 mixture of Pd(OH)2/C and Pd/C. The synthetic potential of the selective ether cleaving ability of Pd(OH)2/C, essentially under neutral conditions, has been demonstrated by an efficient synthesis of a precursor for the preparation of an inositol pyrophosphate derivative.

Elaboration of the ether cleaving ability and selectivity of the classical Pearlman's catalyst [Pd(OH)2/C]: Concise synthesis of a precursor for a myo-inositol pyrophosphate

The cleavage of propargyl, allyl, benzyl, and PMB ethers by Pd(OH) 2/C can be tuned in that order, by varying the reaction conditions. Other moieties such as C-C double bonds, esters, trityl ether, p-bromo and p-nitrobenzyl ethers are stable to these reaction conditions. Cleavage of allyl ethers can be made catalytic by using 1:1 mixture of Pd(OH)2/C and Pd/C. The synthetic potential of the selective ether cleaving ability of Pd(OH)2/C, essentially under neutral conditions, has been demonstrated by an efficient synthesis of a precursor for the preparation of an inositol pyrophosphate derivative.

Two approaches to the synthesis of 9-oxo-and 10-hydroxy-2E-decenoic acids, important components of queen substance and royal jelly of honeybees Apis mellifera

Two approaches to the synthesis of 9-oxo-and 10-hydroxy-2E-decenoic acids, biologically active components of queen substance and royal jelly of honeybees, respectively, were proposed starting with allyl bromide and 1,7-octadiene and using chemo-and regioselective transformations of the common intermediate building block 7-octen-1-ylacetate.

Process for preparing monoesters

A process for preparing monoesters comprises the step of reacting at least one diol with at least one carboxylic acid in a biphasic solvent system, the carboxylic acid being sufficiently water soluble to allow esterification to occur, and the biphasic solvent system comprising water and at least one aprotic solvent in which the resulting monoester has greater solubility than in water.