407-81-8 Usage
Uses
Used in Pharmaceutical Industry:
(E)-1,4-difluorobut-2-ene is used as an intermediate for the synthesis of various pharmaceuticals. Its unique properties allow for the creation of new drugs with potential therapeutic benefits.
Used in Agrochemical Industry:
In the agrochemical industry, (E)-1,4-difluorobut-2-ene is utilized as a building block for the development of new agrochemicals, contributing to the advancement of products for agricultural applications.
Used in Organic Compounds Synthesis:
(E)-1,4-difluorobut-2-ene is used as a key component in the synthesis of various fluorinated organic compounds, which have a wide range of applications in different industries due to their unique properties.
Used in Research Applications:
As a highly reactive compound, (E)-1,4-difluorobut-2-ene is employed as a reagent in organic synthesis for research purposes, enabling the exploration of new chemical reactions and the development of novel compounds.
Safety Precautions:
Due to its flammability and potential health hazards, it is crucial to take proper safety precautions when handling and using (E)-1,4-difluorobut-2-ene to ensure the safety of individuals and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 407-81-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,0 and 7 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 407-81:
(5*4)+(4*0)+(3*7)+(2*8)+(1*1)=58
58 % 10 = 8
So 407-81-8 is a valid CAS Registry Number.
InChI:InChI=1/C4H6F2/c5-3-1-2-4-6/h1-2H,3-4H2/b2-1+
407-81-8Relevant academic research and scientific papers
Reaction of diethylaminosulfur trifluoride with diols
Shellhamer, Dale F.,Anstine, D. Timothy,Gallego, Kelly M.,Ganesh, Brian R.,Hanson, Aaron A.,et al.
, p. 861 - 866 (2007/10/02)
Diethylaminosulfur trifluoride (DAST) reacts with dialcohols to give difluorides, sulfite esters or cyclic ethers depending on the number of carbons separating the two alcohol groups.Vicinal and 1,3-diols give large amounts of sulfite ester products while butane-1,4-diol gives almost exclusively the cyclic ether tetrahydrofuran.Terminal dialcohols longer than four carbons give primarily difluoride products.Semiempirical calculations indicate a preference for cyclic intermediates when four or less carbons separate the two alcohol moieties.These cyclic intermediates lead directly to the cyclic ethers and sulfite ester products.
Oxidative fluorination in amine-HF mixtures
Meurs,Eilenberg
, p. 705 - 714 (2007/10/02)
The selective electrochemical fluorination of alkenes, phenanthroline, naphthalene and chlorobenzene in neat amine-HF mixtures is described, together with the chemistry of 4,4-difluorocyclohexadienone.
