409093-35-2

Upstream product

• 1117-71-1 methyl-4-bromo-2-butenoate 
• 409093-33-0 N-[4-(tert-butyl-dimethyl-silanyloxy)-2-formyl-phenyl]-4-methyl-benzenesulfonamide 
• 4957-34-0 (E)-1-acetoxy-3-bromo-1-propene 
• 760968-80-7 N-(4-benzyloxy-2-formylphenyl)-4-methylbenzenesulfonamide 
• 409093-32-9 5-(tert-butyl-dimethyl-silanyloxy)-2-(toluene-4-sulfonylamino)-benzoic acid methyl ester 
• 760968-78-3 methyl 5-benzyloxy-2-(4-methylbenzenesulfonylamino)benzoate 
• 760968-79-4 N-(4-benzyloxy-2-hydroxymethylphenyl)-4-methylbenzenesulfonamide 
• 760968-77-2 methyl 5-hydroxy-2-(4-methylbenzenesulfonylamino)benzoate 
• 1882-72-0 methyl 2-amino-5-hydroxybenzoate 
• 394-31-0 2-amino-5-hydroxybenzoic acid 

Downstream Products

• 409093-36-3 acetic acid 5-(tert-butyl-dimethyl-silanyloxy)-5-[5-(tert-butyl-dimethyl-silanyloxy)-2-(toluene-4-sulfonylamino)-phenyl]-pent-2-enyl ester 

Relevant academic research and scientific papers

Synthetic studies on bradykinin antagonist martinellines: Construction of a pyrrolo[3,2-c]quinoline skeleton using silicon-tether RCM reaction and allylic amination

The pyrrolo[3,2-c]quinoline consisting of a core structure of martinellines, the first naturally occurring heterocycle, was prepared through silicon-tether ring-closing metathesis reaction and intramolecular allylic amination as key steps. Graphical Abstr

Asymmetric synthesis of tetrahydroquinoline derivative, a building block of martinellines, via intramolecular allylic amination using 9-PBN

A tetrahydroquinoline derivative, a core structure of martinellines, was prepared through intramolecular allylic amination of the racemic precursor with a stereogenic center using 9-PBN and palladium. The reaction proceeded in a reagent-controlled manner