41078-65-3

Usage

Uses

Used in Organic Synthesis:
2-amino-3,4,5,6-tetrahydropyrimidine is used as a building block in organic synthesis for the creation of various pharmaceutical compounds and other organic molecules. Its unique structure and functional groups make it a valuable component in the synthesis of complex organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-amino-3,4,5,6-tetrahydropyrimidine is employed as a key component in the development of new drugs with a wide range of biological activities. Its ability to form diverse chemical structures allows for the exploration of novel therapeutic agents with potential applications in various medical conditions.
Used in Drug Discovery:
2-amino-3,4,5,6-tetrahydropyrimidine plays a significant role in drug discovery, where it is utilized to design and synthesize new chemical entities with potential therapeutic benefits. Its structural diversity and reactivity make it an attractive candidate for the development of innovative pharmaceutical agents.
Used in Pharmaceutical Industry:
2-amino-3,4,5,6-tetrahydropyrimidine is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its presence in the molecular structure of these compounds contributes to their biological activity and therapeutic potential, making it an essential component in the development of new medications.
Overall, 2-amino-3,4,5,6-tetrahydropyrimidine is a versatile and important chemical compound in the fields of organic chemistry, medicinal chemistry, and drug discovery, with applications spanning across various industries and research areas.

Upstream product

• 56-05-3 2-Amino-4,6-dichloropyrimidine 
• 127099-85-8 N-Cyanoguanidine 
• 109-76-2 Trimethylenediamine 
• 1121-60-4 pyridine-2-carbaldehyde 
• 56-18-8 bis(3-aminopropyl)amine 
• 10111-08-7 2-imidazolecarbaldehyde 
• 109-12-6 2-aminopyrimidine 

Downstream Products

• 250688-89-2 (2S)-2-Benzyloxycarbonylamino-3-((5-(2-(1,4,5,6-tetrahydropyrimidin-2-ylcarbamoyl)-cyclopropyl)-thiophene-2-carbonyl)-amino)-propionic Acid tert-Butyl Ester 
• 250688-86-9 2-benzyloxycarbonylamino-3-({5-[2-(1,4,5,6-tetrahydro-pyrimidin-2-ylcarbamoyl)-ethyl]-thiophene-2-carbonyl}-amino)-propionic acid tert-butyl ester 
• 250689-03-3 (2S)-2-(4-tert-Butylphenyl-sulfonylamino)-3-((5-(2-(1,4,5,6-tetrahydropyrimidin-2-ylcarbamoyl)-ethyl)-thiophene-2-carbonyl)-amino)-propionic Acid tert-Butyl Ester 
• 250689-01-1 (2S)-3-((5-(2-(1,4,5,6-Tetrahydropyrimidin-2-ylcarbamoyl)-ethyl)-thiophene-2-carbonyl)-amino)-2-(4-trifluoromethylphenyl-sulfonylamino)-propionic Acid tert-Butyl Ester 
• 250688-99-4 (2S)-3-((5-(2-(1,4,5,6-Tetrahydropyrimidin-2-ylcarbamoyl)-ethyl)-thiophene-2-carbonyl)-amino)-2-(2,4,6-trimethylphenyl-sulfonylamino)-propionic Acid tert-Butyl Ester 
• 393544-39-3 (2S)-2-benzyloxycarbonylamino-3-{2-methyl-7-[3-(1,4,5,6-tetrahydro-pyrimidin-2-ylcarbamoyl)-propyl]-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino}-propionic acid 
• 393544-77-9 (2S)-3-{2-methyl-7-[3-(1,4,5,6-tetrahydro-pyrimidin-2-ylcarbamoyl)-propyl]-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino}-2-(benzenesulfonylamino)-propionic acid tert-butyl ester 
• 393544-81-5 (2S)-3-(2-methyl-7-[3-(1,4,5,6-tetrahydro-pyrimidin-2-ylcarbamoyl)-propyl]-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-2-(4-bromobenzenesulfonylamino)-propionic acid tert-butyl ester 
• 393544-89-3 (2R)-3-{2-methyl-7-[3-(1,4,5,6-tetrahydro-pyrimidin-2-ylcarbamoyl)-propyl]-7H-pyrrolo[2,3-d]pyrimidin-4-ylsulfanyl}-2-(4-bromobenzenesulfonylamino)-propionic acid tert-butyl ester 
• 393545-05-6 (2R)-3-{2-methyl-7-[3-(1,4,5,6-tetrahydro-pyrimidin-2-ylcarbamoyl)-propyl]-7H-pyrrolo[2,3-d]pyrimidin-4-ylsulfanyl}-2-(benzenesulfonylamino)-propionic acid tert-butyl ester 
• 393544-56-4 (2S)-2-benzyloxycarbonylamino-3-{9-[3-(1,4,5,6-tetrahydro-pyrimidin-2-ylcarbamoyl)-propyl]-9H-purin-6-ylamino}-propionic acid tert-butyl ester 
• 372136-56-6 (1,1-dimethylethyl) N-(2-benzothiazolyl)-O-(4-oxo-4-[(1,4,5,6-tetrahydro-2-pyrimidinyl)amino]butyl)-L-tyrosinate 
• 372136-53-3 (1,1-dimethyl ethyl) N-(2-benzoxazolyl)-O-[4-oxo-4-[(1,4,5,6-tetrahydro-2-pyrimidinyl)amino]butyl]-L-tyrosinate 

Relevant academic research and scientific papers

PRODUCTION METHOD OF CYCLIC COMPOUND

PROBLEM TO BE SOLVED: To provide an industrially simple production method of a cyclic compound. SOLUTION: A production method of a cyclic compound includes a step to obtain a reduced form (B) by reducing an unsaturated bond in a ring structure of an aromatic compound (A) by means of catalytic hydrogenation of the aromatic compound (A) or its salt using palladium carbon as a catalyst under a normal pressure, in which the aromatic compound (A) has one or more ring structures selected from a group consisting of a five membered-ring, a six membered-ring, and a condensed ring of the five membered-ring or the six membered-ring with another six membered-ring, a hetero atom can be included in the ring structure, and the aromatic compound (A) can have one or two side chains bonded to the ring structure and does not have any carbon-carbon triple bond in the side chain. SELECTED DRAWING: None COPYRIGHT: (C)2021,JPOandINPIT

Novel vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same

A subject of the invention is the compounds of formula (I): in which R1, R2, R3, R4 and G have the meanings indicated in the description, their preparation process, their use as medicaments having an antagonist activity on the vitronectin receptor and the pharmaceutical compositions containing them.

Symmetrical and unsymmetrical polyalkylamine metal complexes for ligand extraction and generation

Mthods and apparatus for the extraction of a ligand such as molecular oxygen from a first fluid environment and for release of a ligand such as molecular oxygen, as well as ligand carrier compounds therefore comprising linear, pentadentate polyalkylamines and transition metal ions. The carrier compounds have the general formula: STR1 where, each of R1 and R2 is independently an organic group including a sulfur, an oxygen or a nitrogen coordinated to M; each of m, n. o, and p is 1, 2 3, or 4; X is selected from the group consisting of 2,6-pyridyl, 2,6-piperidyl, 2,5pyrrolyl, 2,4-imidazolyl, substituted heterocyclic amines, --O--, --S-- >P--R3, and >N--R3 where R3 is hydrogen, lower alkyl, or aralkyl; and M is a transition metal ion.