412296-63-0

Basic information

• Product Name: Methanone, (2-aminophenyl)(3,4-dimethylphenyl)-
• CAS NO: 412296-63-0
• Molecular Formula: C15H15NO
• Molecular Weight: 225.29
• Mol File: 412296-63-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Methanone, (2-aminophenyl)(3,4-dimethylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (2-aminophenyl)(3,4-dimethylphenyl)-(412296-63-0)
• EPA Substance Registry System: Methanone, (2-aminophenyl)(3,4-dimethylphenyl)-(412296-63-0)

Safety Data

• Hazardous Substances Data: 412296-63-0(Hazardous Substances Data)

Upstream product

• 95-47-6 o-xylene 
• 42840-02-8 2-(Toluene-4-sulfonylamino)-benzoyl chloride 
• 118-92-3 anthranilic acid 
• 6311-23-5 2-(toluene-4-sulfonylamino)-benzoic acid 
• 500315-91-3 toluene-4-sulfonic acid-[2-(3,4-dimethyl-benzoyl)-anilide] 

Downstream Products

• 500870-83-7 2-N-(4-methylsulfonylbenzoyl)-amide-3',4'-dimethyl-benzophenone 
• 500870-84-8 2-N-(4-aminosulfonylbenzoyl)-amide-3',4'-dimethyl-benzophenone 
• 4627-17-2 2,3-dimethyl-9H-fluoren-9-one 
• 93424-27-2 4-(3'.4'-dimethylphenyl)-2-quinolone-3-acetic acid 

Relevant articles and documents

Synthesis and biological evaluation of substituted 2-sulfonyl-phenyl-3-phenyl-indoles: A new series of selective COX-2 inhibitors

A new series of substituted 2-sulfonyphenyl-3-phenyl-indole derivatives were synthesized and evaluated for their ability to inhibit COX-2 and COX-1enzymes. Most of the compounds synthesized were found to be highly potent and selective inhibitors of COX-2. This work led to the discovery of 2-aminosulfonylphenyl-3-phenyl-indole 5a which possesses higher activity and selectivity for COX-2 than Celecoxib both in vitro and in vivo.