6311-23-5

Basic information

• Product Name: AKOS AU36-M212
• Synonyms: RARECHEM AL CB 0779;AKOS AU36-M212;2-{[(4-Methylphenyl)sulfonyl]amino}benzoic acid;2-(TOLUENE-4-SULFONYLAMINO)-BENZOIC ACID;AKOS BBV-010080;ALINDA 103015;LABOTEST-BB LT00000357;OTAVA-BB 1056747
• CAS NO: 6311-23-5
• Molecular Formula: C₁₄H₁₃NO₄S
• Molecular Weight: 291.32
• Mol File: 6311-23-5.mol
• Article Data: 37

Chemical Properties

• Boiling Point: 483.6°C at 760 mmHg
• Flash Point: 246.3°C
• Appearance: /
• Density: 1.404g/cm³
• Vapor Pressure: 3.66E-10mmHg at 25°C
• Refractive Index: 1.641
• CAS DataBase Reference: AKOS AU36-M212(CAS DataBase Reference)
• NIST Chemistry Reference: AKOS AU36-M212(6311-23-5)
• EPA Substance Registry System: AKOS AU36-M212(6311-23-5)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 6311-23-5(Hazardous Substances Data)

Usage

General Description

AKOS AU36-M212 is a chemical compound with the molecular formula C6H6N2O2S. It is a yellow crystalline solid that is used as a pharmaceutical intermediate and in the production of various organic compounds. AKOS AU36-M212 has potential applications in the synthesis of pharmaceutical drugs, agrochemicals, and dyes. It is known for its high purity and stability, making it a valuable reagent in organic synthesis. Additionally, AKOS AU36-M212 has been studied for its potential biological activities and medicinal properties, further expanding its potential uses in the pharmaceutical industry.

InChI:InChI=1/C14H13NO4S/c1-10-6-8-11(9-7-10)20(18,19)15-13-5-3-2-4-12(13)14(16)17/h2-9,15H,1H3,(H,16,17)

Upstream product

• 118-92-3 anthranilic acid 
• 98-59-9 p-toluenesulfonyl chloride 
• 1570134-55-2 N-(2-(4,5-dihydrooxazol-2-yl)phenyl)-2-(4-methylphenylsulfonamido)benzamide 
• 552-16-9 ortho-nitrobenzoic acid 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 88-67-5 2-Iodobenzoic acid 
• 70-55-3 toluene-4-sulfonamide 
• 941-55-9 4-toluenesulfonyl azide 
• 582-25-2 Potassium benzoate 
• 43019-96-1 d₂-benzoyl chloride 
• 4409-84-1 2-deuteriotoluene 
• 95-46-5 2-methylphenyl bromide 
• 98-88-4 benzoyl chloride 
• 65-85-0 benzoic acid 

Downstream Products

• 23346-81-8 3,4-dimethoxyfluoren-9-one 
• 42523-09-1 1,2-dimethoxy-9H-fluoren-9-one 
• 2041-27-2 2,3-Dimethoxyfluoren-9-one 
• 107642-77-3 4-methoxy-3,5-dimethyl-2'-(4-toluenesulphonamino)diphenyl ketone 
• 36192-61-7 2-amino-4'-methoxybenzophenone 
• 934420-92-5 N-(1-cyclohexylcarbamoyl-3-methyl-butyl)-N-(2-hydroxy-ethyl)-2-(toluene-4-sulfonylamino)-benzamide 
• 934420-94-7 N-[(3-bromo-phenyl)-butylcarbamoyl-methyl]-N-(2-hydroxy-ethyl)-2-(toluene-4-sulfonylamino)-benzamide 
• 934420-98-1 N-[cyclohexyl-(1,1,3,3-tetramethyl-butylcarbamoyl)-methyl]-N-(2-hydroxy-ethyl)-2-(toluene-4-sulfonylamino)-benzamide 
• 934420-96-9 N-(benzylcarbamoyl-cyclohexyl-methyl)-N-(2-hydroxy-ethyl)-2-(toluene-4-sulfonylamino)-benzamide 
• 19434-30-1 2-hydroxy-4'-methylbenzophenone 
• 141368-12-9 3-methyl-9-<3--1-propylamino>-fluorene-9-carbonitrile 
• 42239-63-4 2-aminophenyl-(thien-2-yl)methanone 
• 20409-64-7 (2-hydroxyphenyl)(thiophen-2-yl)methanone 
• 486436-64-0 N-(4'-methylbiphenyl-4-yl)methyl-4-[2-(4-methyl-phenylsulphonylamino)-phenylcarbonylamino]-1-methyl-pyrrole-2-carboxylic acid amide 

Relevant articles and documents

Synthesis, Antimicrobial, Anti-virulence and Anticancer Evaluation of New 5(4H)-Oxazolone-Based Sulfonamides

Since the synthesis of prontosil the first prodrug shares their chemical moiety, sulfona-mides exhibit diverse modes of actions to serve as antimicrobials, diuretics, antidiabetics, and other clinical applications. This inspiring chemical nucleus has prom

Nickel-mediated C(sp2)-H amidation in synthesis of secondary sulfonamides via sulfonyl azides as amino source

In this paper, Ni(II)- Catalyzed ortho-amidation of C(sp2)-H bond with sulfonyl azides directed by (quinolin-8-yl) amine (AQ-amine) is described. The method provides a straightforward method for the synthesis of sulfonamides from available sulfonyl azides via the transition-metal-catalyzed C(sp2)-N bond forming reaction. The amidation reactions exhibit high functional group compatibility, which might proceed a Ni(III)/Ni(I) catalytic cycle. We also applied sulfonamide compound in OLEDs, which exhibits the certain application potential in OLEDs field.

Cleavage of Carboxylic Esters by Aluminum and Iodine

A one-pot procedure for deprotecting carboxylic esters under nonhydrolytic conditions is described. Typical alkyl carboxylates are readily deblocked to the carboxylic acids by the action of aluminum powder and iodine in anhydrous acetonitrile. Cleavage of lactones affords the corresponding ω-iodoalkylcarboxylic acids. Aryl acetylates undergo deacetylation with the participation of the neighboring group. This method enables the selective cleavage of alkyl carboxylic esters in the presence of aryl esters.