41369-60-2Relevant articles and documents
Photoredox-Catalyzed Intramolecular Aminodifluoromethylation of Unactivated Alkenes
Zhang, Zuxiao,Tang, Xiaojun,Thomoson, Charles S.,Dolbier, William R.
supporting information, p. 3528 - 3531 (2015/07/28)
A photoredox catalyzed aminodifluoromethylation of unactivated alkenes has been developed in which HCF2SO2Cl is used as the HCF2 radical source. Sulfonamides were active nucleophiles in the final step of a tandem addition/oxidation/cyclization process to form pyrrolidines, and esters were found to cyclize to form lactones. Thus, a variety of pyrrolidines and lactones were obtained in moderate to excellent yield. In order for the cyclization reactions to be efficient, a combination of a copper catalyst (Cu(dap)2Cl) and silver carbonate was crucial to suppressing a competing chloro, difluoroalkylation process.
Highly selective palladium-catalyzed intramolecular chloroamination of unactivated alkenes by using hydrogen peroxide as an oxidant
Yin, Guoyin,Wu, Tao,Liu, Guosheng
supporting information; experimental part, p. 451 - 455 (2012/02/15)
Cheap and clean! A novel Pd-catalyzed oxidative intramolecular chloroamination of unactivated alkenes has been developed by using hydrogen peroxide as an oxidant and CaCl2 as a chlorine source. A series of chlorinated piperidine derivatives has