41369-60-2

Upstream product

• 50-00-0 formaldehyd 
• 7257-26-3 sodium p-toluenesulfinate tetrahydrate 
• 70-55-3 toluene-4-sulfonamide 
• 64-18-6 formic acid 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 657-84-1 sodium tosylate 

Downstream Products

• 106369-24-8 N-[2-Benzyl-3-(2-methyl-[1,3]dioxolan-2-yl)-2-(toluene-4-sulfonyl)-propyl]-4-methyl-benzenesulfonamide 
• 106369-19-1 2-Cyano-2-methyl-3-(toluene-4-sulfonylamino)-propionic acid ethyl ester 
• 70-55-3 toluene-4-sulfonamide 
• 106369-20-4 2-Acetylamino-2-[(toluene-4-sulfonylamino)-methyl]-malonic acid diethyl ester 
• 1094359-56-4 2-allyl-2-[(toluene-4-sulfonylamino)-methyl]-malonic acid dimethyl ester 
• 1094359-57-5 N-(2,2-bis(hydroxymethyl)pent-4-en-1-yl)-4-methylbenzenesulfonamide 
• 1361964-50-2 C₁₆H₂₀ClNO₆S 
• 1361964-67-1 C₁₆H₂₀ClNO₆S 
• 1361964-51-3 C₁₄H₂₀ClNO₄S 
• 1401228-03-2 tert-butyl (2S)-2-{[bis(4-fluorophenyl)methylidene]amino}-3-[(4-methylbenzene)sulfonamido]propanoate 
• 106369-34-0 2-Methyl-4-phenethyl-1-(toluene-4-sulfonyl)-1H-pyrrole 
• 106369-33-9 4-Benzyl-2-methyl-1-(toluene-4-sulfonyl)-1H-pyrrole 
• 106369-32-8 1-(Toluene-4-sulfonyl)-3-undecyl-1H-pyrrole 
• 106369-31-7 3-Phenethyl-1-(toluene-4-sulfonyl)-1H-pyrrole 

Relevant academic research and scientific papers

Photoredox-Catalyzed Intramolecular Aminodifluoromethylation of Unactivated Alkenes

A photoredox catalyzed aminodifluoromethylation of unactivated alkenes has been developed in which HCF2SO2Cl is used as the HCF2 radical source. Sulfonamides were active nucleophiles in the final step of a tandem addition/oxidation/cyclization process to form pyrrolidines, and esters were found to cyclize to form lactones. Thus, a variety of pyrrolidines and lactones were obtained in moderate to excellent yield. In order for the cyclization reactions to be efficient, a combination of a copper catalyst (Cu(dap)2Cl) and silver carbonate was crucial to suppressing a competing chloro, difluoroalkylation process.

Highly selective palladium-catalyzed intramolecular chloroamination of unactivated alkenes by using hydrogen peroxide as an oxidant

Cheap and clean! A novel Pd-catalyzed oxidative intramolecular chloroamination of unactivated alkenes has been developed by using hydrogen peroxide as an oxidant and CaCl2 as a chlorine source. A series of chlorinated piperidine derivatives has

Catalytic asymmetric Mannich reaction of glycine Schiff bases with α-amido sulfones as precursors of aliphatic imines

A general and practical CuI-Fesulphos-catalyzed Mannich reaction of glycinate Schiff bases with aliphatic imines generated in situ from α-amido sulfones is described. Imines with linear and branched alkyl chains, including substrates bearing functional groups, can be efficiently applied. The resulting syn-configured orthogonally protected β-alkyl-α,β-diamino acid derivatives are produced with excellent levels of diastereo- (typically syn/anti >90:10) and enantioselectivity (generally ≥90% ee).

A NEW AND EFFECTIVE AMINOMETHYLATION BY THE USE OF N-(p-TOLUENESULFONYLMETHYL)-p-TOLUENESULFONAMIDE AS AN EQUIVALENT OF METHANIMINE. A CONVENIENT PREPARATION OF PYRROLE COMPOUNDS

Readily available N-(p-toluenesulfonylmethyl)-p-toluenesulfonamide was treated with base to generate N-methylene-p-toluenesulfonamide which reacted with a variety of nucleophiles forming the corresponding N-tosyl-aminomethylated compounds in good yields.Furthermore, the N-tosyl-aminomethylated acetals thus obtained were converted into the corresponding N-tosylpyrroles with the aid of acid catalyst in excellent yields.