4139-78-0

Basic information

• Product Name: Benzenamine, N,N-dimethyl-4-(1-methylethyl)- (9CI)
• Synonyms: Benzenamine, N,N-dimethyl-4-(1-methylethyl)- (9CI);N,N-Dimethyl-4-isopropylaniline
• CAS NO: 4139-78-0
• Molecular Formula: C₁₁H₁₇N
• Molecular Weight: 163.25938
• Product Categories: ISOPROPYL
• Mol File: 4139-78-0.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 236.4°Cat760mmHg
• Flash Point: 95.2°C
• Appearance: /
• Density: 0.919g/cm³
• Vapor Pressure: 0.0476mmHg at 25°C
• Refractive Index: 1.529
• PKA: 5.60±0.12(Predicted)
• CAS DataBase Reference: Benzenamine, N,N-dimethyl-4-(1-methylethyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, N,N-dimethyl-4-(1-methylethyl)- (9CI)(4139-78-0)
• EPA Substance Registry System: Benzenamine, N,N-dimethyl-4-(1-methylethyl)- (9CI)(4139-78-0)

Safety Data

• Hazardous Substances Data: 4139-78-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H17N/c1-9(2)10-5-7-11(8-6-10)12(3)4/h5-9H,1-4H3

Upstream product

• 80041-89-0 isopropylboronic acid 
• 698-69-1 4-chloro-N,N-dimethylaniline 
• 124-38-9 carbon dioxide 
• 99-88-7 4-Isopropylaniline 
• 59576-30-6 2-methyl-1-(pyridin-2-yl)propan-1-one 
• 586-77-6 4-bromo-N,N-dimethylaniline 
• 83026-55-5 2-<4-(dimethylamino)phenyl>-2-propanol 
• 1888-75-1 isopropyllithium 
• 50-00-0 formaldehyd 
• 920-39-8 isopropylmagnesium bromide 
• 113556-00-6 p-(dimethylamino)phenyl dodecyl sulfide 
• 77-78-1 dimethyl sulfate 
• 75-16-1 methylmagnesium bromide 
• 100-10-7 4-dimethylamino-benzaldehyde 

Downstream Products

• 678981-79-8 2-dimethylamino-5-isopropyl-benzyl alcohol 
• 5259-66-5 isopropyl-4 cyclohexene-3 one-1 
• 1346855-01-3 1-(2-(dimethylamino)-5-isopropylphenyl)naphthalene-2-ol 
• 325142-91-4 4,4,5,5-tetramethyl-2-[4-(propan-2-yl)phenyl]-1,3,2-dioxaborolane 
• 6950-79-4 para-isopropyl-N-methylaniline 
• 861538-22-9 (4-isopropyl-phenyl)-methyl-carbamonitrile 

Relevant articles and documents

Halogen-Bridged Methylnaphthyl Palladium Dimers as Versatile Catalyst Precursors in Coupling Reactions

Halogen-bridged methylnaphthyl (MeNAP) palladium dimers are presented as multipurpose Pd-precursors, ideally suited for catalytic method development and preparative organic synthesis. By simply mixing with phosphine or carbene ligands, they are in situ converted into well-defined monoligated complexes. Their catalytic performance was benchmarked against state-of-the-art systems in challenging Buchwald–Hartwig, Heck, Suzuki and Negishi couplings, and ketone arylations. Their use enabled record-setting activities, beyond those achievable by optimization of the ligand alone. The MeNAP catalysts permit syntheses of tetra-ortho-substituted arenes and bulky anilines in near-quantitative yields at room temperature, allow mono-arylations of small ketones, and enable so far elusive cross-couplings of secondary alkyl boronic acids with aryl chlorides.

Pd-Catalyzed Alkylation of (Iso)quinolines and Arenes: 2-Acylpyridine Compounds as Alkylation Reagents

The first Pd-catalyzed alkylation of (iso)quinolines and arenes is reported. The readily available and bench-stable 2-acylpyridine compounds were used as an alkylation reagent to form the structurally versatile alkylated (iso)quinolines and arenes. The method affords a convenient pathway for the introduction of alkyl groups into organic molecules.

Base-oxidant promoted metal-free N-demethylation of arylamines

A metal-free oxidative N-demethylation of arylamines with triethylamine as a base and tert-butyl hydroperoxide (TBHP) as oxidant is reported in this paper. The reaction is general, practical, inexpensive, non-toxic, and the method followed is environmentally benign, with moderate to good yields. [Figure not available: see fulltext.]