41436-07-1

Upstream product

• 105-36-2 ethyl bromoacetate 
• 1896-62-4 (E)-benzalacetone 
• 100-42-5 styrene 
• 130484-18-3 ethyl (2Z,4E)-3-methylhexa-2,4-dienoate 
• 623-73-4 diazoacetic acid ethyl ester 
• 122-57-6 1-Phenylbut-1-en-3-one 
• 1403959-51-2 ethyl 5-hydroxy-5-phenylpenta-2,3-dienoate 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 20430-09-5 (2Z,4E)-3-methyl-5-phenylpenta-2,4-dienoic acid 
• 20430-13-1 (2E,4E)-3-methyl-5-phenyl-2,4-pentadienoic acid 

Relevant academic research and scientific papers

Selective synthesis of (2Z,4E)-dienyl esters by ene-diene cross metathesis

(Chemical Equation Presented) Cross metathesis of terminal alkenes with methyl (2Z4E)-hexadienoate and related dienyl esters provides substituted (2Z,4E)-dienyl esters in good yields. Small-scale reactions are effectively promoted by the standard second-g

Sigmatropic rearrangement of allenic alcohols: Stereoselective synthesis of 1,3-diene-2-ol sulfonates

An efficient synthetic pathway to 1,3-diene-2-ol sulfonates involving the [3,3]-sigmatropic rearrangement of allenic alcohols with sulfonic acids under mild reaction conditions is described. These products can easily undergo reduction or transition-metal catalyzed cross-coupling reactions to yield a series of stereodefined multisubstituted 1,3-dienes.

A newly-designed PE-supported arsine for efficient and practical catalytic Wittig olefination

A newly designed PE-supported arsine has been developed as an excellent catalyst for catalytic Wittig-type olefination. Simple ketones, in particular inactive ketones prove to be suitable substrates for the first time. This reaction provides an easy access to di-, tri-, and tetra-substituted olefins in high yield.

Ruthenium-catalyzed tandem cross-metathesis/wittig olefination: Generation of conjugated dienoic esters from terminal olefins

In the presence of ruthenium-based olefin metathesis catalysts and triphenylphosphine, α,β-unsaturated aldehydes can be olefinated with diazoacetates. This ruthenium-catalyzed transformation has been employed in tandem with olefin cross-metathesis to convert terminal olefins into 1,3-dienoic esters in a single operation.

Acid-promoted olefination of ketones by an iron(III) porphyrin complex

(Matrix presented) The acid-promoted olefination of unactivated ketones with diazo reagents in the presence of triphenylphosphine can be catalyzed by the commercially available iron(III) porphyrin complex Fe(TPP)Cl. The reactions were effectively carried out under mild conditions in a one-pot fashion with the use of a stoichiometric diazo reagents and substoichiometric benzoic acid. Examples include aromatic, aliphatic, cyclic, and unsaturated ketones with ethyl diazoacetate or tert-butyl diazoacetate.