4152-39-0Relevant academic research and scientific papers
MBA-cross-linked poly(N-vinyl-2-pyrrolidone)/ferric chloride macromolecular coordination complex as a novel and recyclable Lewis acid catalyst: Synthesis, characterization, and performance toward for regioselective ring-opening alcoholysis of epoxides
Rahmatpour, Ali,Zamani, Maryam
, (2021/09/30)
A novel macromolecular-metal coordination complex, MBA-cross-linked PNVP/FeCl3 material was fabricated by immobilization of water intolerant ferric chloride onto the porous cross-linked poly(N-vinyl-2-pyrrolidone) carrier beads as a macromolecular ligand or carrier which was prepared by suspension free-radical copolymerization of N-vinyl-2-pyrrolidone (NVP) and N,N′-methylene bis-acrylamide (MBA) as a crosslinking agent in water. The obtained PNVP/FeCl3 was characterized by UV/vis and FT-IR spectroscopies, TGA, FE-SEM, EDX, and ICP techniques. This heterogenized version of ferric chloride is a convenient and safe alternative to highly water intolerant ferric chloride. The catalytic performance of (PNVP/FeCl3) as an efficient and recyclable polymeric Lewis acid catalyst was appropriately probed in the regio-and stereoselective nucleophilic ring opening of various epoxides with various alcohols in excellent yields with TOF up to 182.48 h?1 without generating any waste. The activity data indicate that this heterogeneous catalyst is very active and could be easily recovered, and reused at least six times without appreciable loss of activity indicating its stability under experimental conditions.
Selectivity Paradigm in Lipase Reactions: Correlating Actual and Observed Regioselectivity in Hydrolysis of Unsymmetrical Diacetates
Desai, Shrivallabh B.,Argade, Narshinha P.,Ganesh, Krishna N.
, p. 8105 - 8107 (2007/10/03)
The first simple method using labeling technique has been developed to confirm the actual and observed selectivities in the enzymatic hydrolysis of unsymmetrical diacetates and to measure the enzyme selectivity efficiency. The simple method consists of enzymatic hydrolysis of unsymmetrical diacetate followed by labeling of the hydroxyacetate formed with CD3COOD/DCC and enzymatic rehydrolysis of the labeled compound under the identical set of reaction conditions to estimate the amount of label retained by 1H NMR spectroscopy. The amount of label lost directly indicates the extent of regioselective action of the enzyme.
Regio- and enantioselective esterifications of polyoxygenated compounds catalyzed by lipases
Herradon,Cueto,Morcuende,Valverde
, p. 845 - 864 (2007/10/02)
The lipase catalyzed esterifications of derivatives of propane-1,2,3-triol and butane 1,2,4-triol in organic solvents have been studied. The influence of several factors (lipase source, organic solvent, additives and structural variations in the substrate
Enatioselective Microbial Reduction of Monoesters of 1,3-Dihydroxypropanone: Synthesis of (S)- and (R)-1,2-O-Isopropylideneglycerol
Aragozzini, Fabrizio,Maconi, Elisabetta,Potenza, Donatella,Scolastico, Carlo
, p. 225 - 227 (2007/10/02)
The reduction of 3-benzoyloxy-1-hydroxypropanone with bakers' yeast proceeds enantioselectively to afford (S)-3-benzoyloxy-1,2-propanediol, which may be further converted into (S)-(benzoyloxymethyl)oxirane.The bioreduction with fermenting yeast of 1-acetoxy-3-benzyloxypropanones gives (R)-1-benzyloxy-3-acetoxy-2-propanol which can be used for the preparation of both (S)- and (R)-1,2-O-isopropylideneglycerol.
HIGHLY REGIOSELECTIVE RING OPENING OF EPOXIDES WITH ALCOHOLS CATALYZED BY ORGANOTIN PHOSPHATE CONDENSATES
Otera, Junzo,Yoshinaga, Yukari,Hirakawa, Kazuhisa,Nakata, Tetsuya
, p. 3219 - 3222 (2007/10/02)
Organotin phosphate condensates proved to catalyze the ring opening reaction of epoxides with alcohols in a highly regioselective manner.
