6387-89-9

Basic information

• Product Name: 2-Oxiranemethanol,2-acetate
• Synonyms: 1-Propanol,2,3-epoxy-, acetate (7CI,8CI);Glycidol acetate (6CI);Oxiranemethanol, acetate(9CI);(?à)-Glycidyl acetate;Glycidylacetate;Oxiranemethyl acetate
• CAS NO: 6387-89-9
• Molecular Formula: C₅H₈O₃
• Molecular Weight: 116.1152
• EINECS: 228-994-3
• Mol File: 6387-89-9.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 146.7 °C at 760 mmHg
• Flash Point: 69.6 °C
• Appearance: solid
• Density: 1.140g/cm³
• Vapor Pressure: 4.59mmHg at 25°C
• Refractive Index: 1.434
• Storage Temp.: 2-8°C
• Solubility: H2O: soluble
• CAS DataBase Reference: 2-Oxiranemethanol,2-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxiranemethanol,2-acetate(6387-89-9)
• EPA Substance Registry System: 2-Oxiranemethanol,2-acetate(6387-89-9)

Safety Data

• Hazard Codes: Xn:Harmful
• Statements: R22:
• Safety Statements: S36:
• WGK Germany: 3
• RTECS: SA9230000
• Hazardous Substances Data: 6387-89-9(Hazardous Substances Data)

Usage

General Description

2-Oxiranemethanol,2-acetate, also known as glycidyl acetate, is a chemical compound which falls under the category of epoxides - a group of reactive organic compounds characterized by an oxygen atom bound to two adjacent carbon atoms of a molecular backbone. This chemical is particularly used in industry as a reactive diluent for high viscosity epoxy resins in the formulation of paints, inks and adhesives. It is also utilized in pharmaceuticals, coating systems, and in the synthesis of other chemicals. Its properties include its flammability, irritability to the eyes and skin, and its ability to cause harm if swallowed or inhaled.

InChI:InChI=1/C5H8O3/c1-4(6)7-2-5-3-8-5/h5H,2-3H2,1H3

Upstream product

• 463-51-4 Ketene 
• 556-52-5 oxiranyl-methanol 
• 106-89-8 epichlorohydrin 
• 64-19-7 acetic acid 
• 141-52-6 sodium ethanolate 
• 108-24-7 acetic anhydride 
• 141-78-6 ethyl acetate 
• 108-22-5 Isopropenyl acetate 
• 127-09-3 sodium acetate 
• 591-87-7 Allyl acetate 
• 24573-30-6 3-chloro-2-hydroxy-1-propyl acetate 
• 127-08-2 potassium acetate 
• 79-21-0 peracetic acid 
• 108-05-4 vinyl acetate 

Downstream Products

• 121485-48-1 4-acetoxymethyl-3-phenyl-oxazolidin-2-one 
• 4152-39-0 1-O-acetyl-3-O-benzylpropane-1,2,3-triol 
• 556-52-5 oxiranyl-methanol 
• 592-20-1 Acetol acetate 
• 57044-25-4 (R)-oxiranemethanol 
• 60456-23-7 (S)-oxiranemethanol 
• 105-70-4 2-hydroxypropane-1,3-diyl diacetate 
• 102-62-5 diacetin 
• 1351288-29-3 CF₃O₃S^(1-)*C₂₄H₃₁N₂O₂⁽¹⁺⁾ 
• 19405-98-2 (S)-β-acetoxy-γ-butyrolactone 
• 22741-52-2 1-tert-butylamino-2,3-dihydroxypropane 
• 70445-33-9 1-O-(2-ethylhexyl)glycerin 
• 1260495-17-7 2-hydroxy-3-(4-phenyl-1H-1,2,3-triazol-1-yl)propyl acetate 

Relevant articles and documents

3-(Acyloxy)propanolamines: agents with β-adrenergic blocking activity

A series of totally aliphatic 3-(acyloxy)propanolamine derivatives were prepared and their pA2-values were determined employing the guinea-pig atrium.Compounds, with an acetyl or methyl succinoyl half ester moiety showed a pronounced β1-adrenergic blocking activity.Keywords: 3-(acyloxy)propanolamines / β1-adrenergic blocking activity

Poly(Alkyl Glycidate Carbonate)s as Degradable Pressure-Sensitive Adhesives

Insertion of CO2 into the polyacrylate backbone, forming poly(carbonate) analogues, provides an environmentally friendly and biocompatible alternative. The synthesis of five poly(carbonate) analogues of poly(methyl acrylate), poly(ethyl acrylate), and poly(butyl acrylate) is described. The polymers are prepared using the salen cobalt(III) complex catalyzed copolymerization of CO2 and a derivatized oxirane. All the carbonate analogues possess higher glass-transition temperatures (Tg=32 to ?5 °C) than alkyl acrylates (Tg=10 to ?50 °C), however, the carbonate analogues (Td≈230 °C) undergo thermal decomposition at lower temperatures than their acrylate counterparts (Td≈380 °C). The poly(alkyl carbonates) exhibit compositional-dependent adhesivity. The poly(carbonate) analogues degrade into glycerol, alcohol, and CO2 in a time- and pH-dependent manner with the rate of degradation accelerated at higher pH conditions, in contrast to poly(acrylate)s.

Composites of [γ-H2PV2W10O40]3- and [α-SiW12O40]4- supported on Fe2O3 as heterogeneous catalysts for selective oxidation with aqueous hydrogen peroxide

Composites of [γ-H2PV2W10O40]3- and [α-SiW12O40]4- supported on Fe2O3 (PV2-SiW12/Fe2O3, in particular, the molar ratio of PV2/SiW12 = 1/1) could act as effective and reusable heterogeneous catalysts for selective oxidation with aqueous hydrogen peroxide. In the presence of PV2-SiW12/Fe2O3, various kinds of organic substrates such as alkenes, sulfides, arenes, and alkanes could selectively be converted into the corresponding oxygenated products in moderate to high yields. The observed catalyses for the present oxidations were intrinsically heterogeneous, and PV2-SiW12/Fe2O3 could be reused at least three times for each oxidation (epoxidation, sulfoxidation, and arene hydroxylation) without appreciable losses of the high catalytic performance.