4192-32-9

Usage

Uses

Used in Organic Synthesis:
5-(2-Bromo-acetyl)-thiophene-2-carboxylic acid methyl ester is used as a synthetic intermediate in the production of various organic compounds. Its bromine atom makes it a versatile building block for the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Polymer Production:
The ester functional group in 5-(2-Bromo-acetyl)-thiophene-2-carboxylic acid methyl ester aids in increasing its solubility, making it a potential candidate for the production of polymers. It can be used as a monomer or a comonomer in the synthesis of polymers with specific properties, such as flame retardancy or improved mechanical strength.
Used in Chemical Research:
5-(2-Bromo-acetyl)-thiophene-2-carboxylic acid methyl ester can be employed as a research tool in the field of chemistry. Its unique structure and properties make it suitable for studying various chemical reactions and mechanisms, as well as for the development of new synthetic methods and techniques.
Used in Flame Retardant Industry:
Due to the presence of the bromine atom, 5-(2-Bromo-acetyl)-thiophene-2-carboxylic acid methyl ester can be used as a flame retardant additive in various materials, such as plastics, textiles, and coatings. The bromine atom helps to slow down the combustion process, improving the fire resistance of the materials.
Used in Environmental Applications:
5-(2-Bromo-acetyl)-thiophene-2-carboxylic acid methyl ester can be utilized in environmental applications, such as the remediation of contaminated soil or water. Its acidic properties and reactivity with certain pollutants make it a potential candidate for the development of new environmental treatment technologies.

Upstream product

• 186581-53-3 diazomethane 
• 133380-41-3 methyl 5-(chlorocarbonyl)thiophene-2-carboxylate 
• 67808-64-4 5-formyl-thiophene-2-carboxylic acid methyl ester 
• 4101-81-9 methyl 5-acetyl-2-thiophenecarboxylate 
• 4066-41-5 5-acetylthiophene-2-carboxylic acid 
• 50340-79-9 thiophene-2,5-dicarboxylic acid monomethyl ester 
• 4565-31-5 5-formyl-2-thiophencarboxylic acid 

Downstream Products

• 133380-53-7 5-(2-phenyloxazol-5-yl)-2-thiophenecarboxylic acid 
• 133380-51-5 methyl 5-(2-phenyloxazol-5-yl)-2-thiophenecarboxylate 
• 133380-49-1 methyl 5--2-thiophenecarboxylate 
• 4045-03-8 2-(thiophen-2-yl)imidazo[1,2-a]pyridine 
• 499770-66-0 5-(2-methyl-1,3-thiazol-4-yl)thiophene-2-carboxaldehyde 

Relevant academic research and scientific papers

Dihydroquinozolinone antiport process blocking agent, and preparation method and application thereof

The invention belongs to the field of pharmaceutical and chemical industry, and relates to dihydroquinozolinone antiport process blocking agent, and a preparation method and application thereof, in particular to a novel dihydroquinozolinone antiport process blocking agent compound, a medicinal salt, isomer, hydrate and solvate thereof, application of the compound and the medicinal salt, isomer, hydrate and solvate thereof to preparation of drugs for preventing and/or first aiding diseases caused by ribosome-inactivating proteins, and application of the compound and the medicinal salt, isomer,hydrate and solvate thereof to preparation of drugs for preventing and/or curing diseases caused by enterovirus, filoviridae or polyomavirus. The compound can effectively resist II-type ribosome-inactivating protein poisoning and/or the diseases caused by enterovirus, filoviridae or polyomavirus.

FACTOR XIa INHIBITORS

The present invention provides a compound of Formula (I); and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma kallikrein.

AMIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR

The present invention provides compounds usuful for prevention, treatment or allevation of diseases against which activation of the thrombopoietin receptor is effective. A compound represented by the formula (1): wherein A, B, R1, L1

THIOPHENE -2- CARBOXYLIC ACID - (1H - BENZIMIDAZOL - 2 YL) - AMIDE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF THE TEC KINASE ITK (INTERLEUKIN -2- INDUCIBLE T CELL KINASE) FOR THE TREATMENT OF INFLAMMATION, IMMUNOLOGICAL AND ALLERGIC DISORDERS

Disclosed are compounds of formula (I): wherein Ar1, Ar2, R1, R2, R3, R4 and Xa are defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for

Bicyclyl or heterobicyclylmethanesulfonylamino-substituted n-hydroxyformamides

Compounds of formula (I): R is hydrogen, alkyl, alkenyl, alkynyl, aryl, heteroaryl or heterocyclyl; and R1 is bicyclyl or heterobicyclyl, are useful in the treatment and prophylaxis of conditions mediated by s-CD23.