4101-81-9

Basic information

• Product Name: Methyl 5-Acetylthiophene-2-carboxylate
• Synonyms: Methyl 5-Acetylthiophene-2-carboxylate;5-Acetyl-thiophene-2-carboxylicacidMethylester
• CAS NO: 4101-81-9
• Molecular Formula: C₈H₈O₃S
• Molecular Weight: 184.22
• Mol File: 4101-81-9.mol
• Article Data: 10

Chemical Properties

• Melting Point: 137-138 °C
• Boiling Point: 127-128 °C(Press: 1 Torr)
• Appearance: /
• Density: 1.241±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Methyl 5-Acetylthiophene-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 5-Acetylthiophene-2-carboxylate(4101-81-9)
• EPA Substance Registry System: Methyl 5-Acetylthiophene-2-carboxylate(4101-81-9)

Safety Data

• Hazardous Substances Data: 4101-81-9(Hazardous Substances Data)

Usage

General Description

Methyl 5-Acetylthiophene-2-carboxylate is a chemical compound with the molecular formula C10H10O3S. It is a derivative of thiophene and is commonly used in the pharmaceutical and flavor industries. Methyl 5-Acetylthiophene-2-carboxylate has a strong odor and is known for its fruity, nutty, and roasted scent. It is often used as a flavoring agent in the food industry and as a key intermediate in the synthesis of various pharmaceutical compounds. Methyl 5-Acetylthiophene-2-carboxylate is also used in the production of fragrances, dyes, and other specialty chemicals. It is important to handle this compound with care as it can be harmful if ingested and may cause irritation to the skin and eyes.

Upstream product

• 4066-41-5 5-acetylthiophene-2-carboxylic acid 
• 74-88-4 methyl iodide 
• 88-15-3 2-Acetylthiophene 
• 67-56-1 methanol 
• 56-23-5 tetrachloromethane 
• 18107-18-1 diazomethyl-trimethyl-silane 

Downstream Products

• 499770-66-0 5-(2-methyl-1,3-thiazol-4-yl)thiophene-2-carboxaldehyde 
• 68257-90-9 5-(2-bromoacetyl)thiophene-2-carboxamide 
• 68257-89-6 5-acetylthiophene-2-carboxamide 
• 101540-26-5 arotinolol hydrochloride 
• 52560-89-1 5-(2-mercapto-1,3-thiazol-4-yl)-2-thiophene carboxamide 
• 1332871-47-2 5-(1-{[(2-fluorophenyl)sulfonyl]amino}ethyl)-N-hydroxythiophene-2-carboxamide 
• 4192-32-9 2-bromo-1-(5-methoxycarbonylthiophen-2-yl)-ethanone 

Relevant articles and documents

Preparation method of arotinolol hydrochloride

The invention provides a preparation method of arotinolol hydrochloride, which comprises the following steps of: reacting a compound shown as a structural formula VIII with absolute methanol in the presence of concentrated sulfuric acid to obtain a compou

FACTOR XIa INHIBITORS

The present invention provides a compound of Formula (I); and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma kallikrein.

3-OXO-TETRAHYDRO-FURO[3,2-B]PYRROL-4(5H)-YL) DERIVATIVES II

The invention relates to amidic oxotetrahydro-2H-furo[3.2-b]pyrrol-4(5H)-yl) derivatives as dual CatS/K inhibitors exhibiting a pronounced CatK-inhibition, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.