4209-04-5

Basic information

• Product Name: 2-CHLORO-1-(4-IODOPHENYL)ETHANONE
• Synonyms: 2-Chloro-1-(4-iodophenyl)ethanone; ethanone, 2-chloro-1-(4-iodophenyl)-
• CAS NO: 4209-04-5
• Molecular Formula: C₈H₆ClIO
• Molecular Weight: 280.4901
• Mol File: 4209-04-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 148-150 °C
• Boiling Point: 325.2°Cat760mmHg
• Flash Point: 150.5°C
• Appearance: /
• Density: 1.816g/cm³
• Vapor Pressure: 0.000234mmHg at 25°C
• Refractive Index: 1.617
• CAS DataBase Reference: 2-CHLORO-1-(4-IODOPHENYL)ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-1-(4-IODOPHENYL)ETHANONE(4209-04-5)
• EPA Substance Registry System: 2-CHLORO-1-(4-IODOPHENYL)ETHANONE(4209-04-5)

Safety Data

• Hazardous Substances Data: 4209-04-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H6ClIO/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4H,5H2

Upstream product

• 68120-56-9 1-(4-iodophenyl)ethanol 
• 52470-94-7 2-diazo-1-(4-iodophenyl)ethanone 
• 591-50-4 iodobenzene 
• 79-04-9 chloroacetyl chloride 
• 92527-07-6 1-(4-(dichloro-λ³-iodanyl)phenyl)ethan-1-one 

Downstream Products

• 66121-86-6 4-[4-(4-iodo-phenyl)-thiazol-2-ylamino]-benzenesulfonamide 
• 66122-16-5 4-[4-(4-iodo-phenyl)-thiazol-2-ylamino]-3-methyl-benzenesulfonamide 
• 66122-06-3 4-[4-(4-iodo-phenyl)-thiazol-2-ylamino]-2-methyl-benzenesulfonamide 
• 66121-96-8 2-[4-(4-iodo-phenyl)-thiazol-2-ylamino]-5-methyl-benzenesulfonamide 
• 832096-07-8 2,2-dichloro-1-(4-iodophenyl)ethan-1-one 
• 90842-69-6 (2-(4-iodophenyl)-2-oxoethyl) acetate 
• 619-58-9 4-iodobenzoic acid 
• 18276-79-4 diethyl (1-(4-iodophenyl)vinyl)phosphate 
• 113813-55-1 [2-Chloro-1-hydroxy-1-(4-iodo-phenyl)-ethyl]-phosphonic acid diethyl ester 
• 13329-40-3 4-Iodoacetophenone 
• 113813-47-1 [2-Chloro-1-hydroxy-1-(4-iodo-phenyl)-ethyl]-phosphonic acid dimethyl ester 
• 113813-44-8 Phosphoric acid 1-(4-iodo-phenyl)-vinyl ester dimethyl ester 

Relevant articles and documents

Facile and efficient preparation of α-halomethyl ketones from α-diazo ketones catalyzed by iron(III) halides and silica gel

An efficient and mild method for the synthesis of α-halomethyl ketones from α-diazo ketones was developed using ferric chloride or bromide as the halogen source and silica gel as the hydrogen source, with good to excellent yields.

Chemoenzymatic synthesis of enantiomerically pure terminal 1,2-diols

A new practical method for the enzymatic synthesis of 1,2-diols has been developed by employing a lipase catalyzed one-pot transesterification protocol. A series of substituted α-acetoxyphenylethanones 3a-g have been reduced to the corresponding alcohols under mild conditions employing sodium borohydride and moist neutral alumina, and further subjected for lipase catalyzed irreversible transesterification in the same pot to give mono- and diacetate diols (R)-4 and (S)-5, which on hydrolysis afforded terminal 1,2-diols, (R)- and (S)-6 in high enantiomeric excess.