422507-45-7Relevant articles and documents
Synthesis of the tetracyclic ABCD ring systems of madangamines D-F
Diaba, Fa??za,Pujol-Grau, Climent,Mart??nez-Laporta, Agust??n,Fern??ndez, Israel,Bonjoch, Josep
, p. 568 - 571 (2015/03/04)
Synthesis of the tetracyclic cores of madangamines D-F was achieved, featuring a reductive radical process from an ethoxycarbonyldichloroacetamide to build the morphan nucleus, a Mitsunobu-type aminocyclization toward the common diazatricyclic intermediate, and ring-closing metathesis reactions for the macrocyclization step leading to the 13- to 15-membered rings.
