42275-47-8 Usage
Uses
Used in Pharmaceutical Industry:
2-CHLORO-N-METHYLPROPANAMIDE is used as a key intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and improving the efficacy of existing ones. Its ability to introduce the chloromethyl group into organic compounds facilitates the creation of novel chemical entities with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-CHLORO-N-METHYLPROPANAMIDE is utilized as an intermediate in the production of agrochemicals, such as pesticides and herbicides. Its role in the synthesis of these compounds helps to enhance crop protection and contribute to increased agricultural productivity.
Used in Organic Synthesis:
2-CHLORO-N-METHYLPROPANAMIDE is employed as a valuable reagent in organic synthesis, where it is used to introduce the chloromethyl group into a wide range of organic compounds. This functionality allows for further reactions and the development of new organic compounds with diverse applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 42275-47-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,2,7 and 5 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 42275-47:
(7*4)+(6*2)+(5*2)+(4*7)+(3*5)+(2*4)+(1*7)=108
108 % 10 = 8
So 42275-47-8 is a valid CAS Registry Number.
InChI:InChI=1/C4H8ClNO/c1-3(5)4(7)6-2/h3H,1-2H3,(H,6,7)
42275-47-8Relevant academic research and scientific papers
Investigation of the synthetic and mechanistic aspects of the highly stereoselective transformation of α-thioamides to α-thio-β- chloroacrylamides
Murphy, Maureen,Lynch, Denis,Schaeffer, Marcel,Kissane, Marie,Chopra, Jay,O'Brien, Elisabeth,Ford, Alan,Ferguson, George,Maguire, Anita R.
, p. 1228 - 1241 (2008/02/03)
Treatment of a series of α-thioamides with N-chlorosuccinimide results in efficient transformation to the analogous α-thio-β- chloroacrylamides. The mechanistic pathway has been established through isolation and characterisation of intermediate compounds. The scope of the transformation has been explored - aryl and alkylthio substituents, primary, secondary and tertiary amides can be employed. In most instances, the chloroacrylamides are formed exclusively as the Z-stereoisomer; however, with tertiary propanamides or with amides derived from butanoic or pentanoic acid a mixture of E- and Z-stereoisomers is formed. The Royal Society of Chemistry.
