42275-47-8 Usage
General Description
2-CHLORO-N-METHYLPROPANAMIDE, also known as N-Chloro-N-methylpropionamide, is an organic compound with the chemical formula C4H8ClNO. It is a white crystalline solid that is commonly used as an intermediate in the production of pharmaceuticals and agrochemicals. This chemical is an amide derivative, which means it contains a carbonyl group attached to an amine functional group. It is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, as well as in the manufacturing of other organic compounds. 2-CHLORO-N-METHYLPROPANAMIDE is also an important reagent in organic synthesis, as it can be used to introduce the chloromethyl group into various organic compounds for further reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 42275-47-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,2,7 and 5 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 42275-47:
(7*4)+(6*2)+(5*2)+(4*7)+(3*5)+(2*4)+(1*7)=108
108 % 10 = 8
So 42275-47-8 is a valid CAS Registry Number.
InChI:InChI=1/C4H8ClNO/c1-3(5)4(7)6-2/h3H,1-2H3,(H,6,7)
42275-47-8Relevant articles and documents
Investigation of the synthetic and mechanistic aspects of the highly stereoselective transformation of α-thioamides to α-thio-β- chloroacrylamides
Murphy, Maureen,Lynch, Denis,Schaeffer, Marcel,Kissane, Marie,Chopra, Jay,O'Brien, Elisabeth,Ford, Alan,Ferguson, George,Maguire, Anita R.
, p. 1228 - 1241 (2008/02/03)
Treatment of a series of α-thioamides with N-chlorosuccinimide results in efficient transformation to the analogous α-thio-β- chloroacrylamides. The mechanistic pathway has been established through isolation and characterisation of intermediate compounds. The scope of the transformation has been explored - aryl and alkylthio substituents, primary, secondary and tertiary amides can be employed. In most instances, the chloroacrylamides are formed exclusively as the Z-stereoisomer; however, with tertiary propanamides or with amides derived from butanoic or pentanoic acid a mixture of E- and Z-stereoisomers is formed. The Royal Society of Chemistry.
